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HandWiki. Depersonalization Disorder. Encyclopedia. Available online: https://encyclopedia.pub/entry/36017 (accessed on 22 September 2026).
HandWiki. Depersonalization Disorder. Encyclopedia. Available at: https://encyclopedia.pub/entry/36017. Accessed September 22, 2026.
HandWiki. "Depersonalization Disorder" Encyclopedia, https://encyclopedia.pub/entry/36017 (accessed September 22, 2026).
HandWiki. (2022, November 23). Depersonalization Disorder. In Encyclopedia. https://encyclopedia.pub/entry/36017
HandWiki. "Depersonalization Disorder." Encyclopedia. Web. 23 November, 2022.
Depersonalization Disorder
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The content is sourced from: https://handwiki.org/wiki/Medicine:Depersonalization_disorder

Depersonalization disorder (DPD), also known as depersonalization/derealization disorder (DPDR), is a mental disorder in which the person has persistent or recurrent feelings of depersonalization or derealization. Depersonalization is described as feeling disconnected or detached from one's self. Individuals experiencing depersonalization may report feeling as if they are an outside observer of their own thoughts or body, and often report feeling a loss of control over their thoughts or actions. In some cases, individuals may be unable to accept their reflection as their own, or they may have out-of-body experiences. Derealization is described as detachment from one's surroundings. Individuals experiencing derealization may report perceiving the world around them as foggy, dreamlike/surreal, or visually distorted. In addition to these depersonalization-derealization disorder symptoms, the inner turmoil created by the disorder can result in depression, self-harm, low self-esteem, phobias, panic attacks, and suicide. It can also cause a variety of physical symptoms, including chest pain, blurry vision, visual snow, nausea, and the sensation of pins and needles in one's arms or legs. Depersonalization-derealization disorder is thought to be caused largely by interpersonal trauma such as childhood abuse. Triggers may include significant stress, panic attacks, and drug use. Studies suggest a uniform syndrome for chronic depersonalization/derealization regardless of whether drugs or an anxiety disorder is the precipitant. It is unclear whether genetics plays a role; however, there are many neurochemical and hormonal changes in individuals with depersonalization disorder. The disorder is typically associated with cognitive disruptions in early perceptual and attentional processes. Diagnostic criteria for depersonalization-derealization disorder include persistent or recurrent feelings of detachment from one's mental or bodily processes or from one's surroundings. A diagnosis is made when the dissociation is persistent and interferes with the social or occupational functions of daily life. However, accurate descriptions of the symptoms are hard to provide due to the subjective nature of depersonalization and derealization and persons' ambiguous use of language when describing these episodes. In the DSM-5, it was combined with derealization disorder and renamed "depersonalization/derealization disorder" ("DDPD"). In the DSM-5, it remains classified as a dissociative disorder, while the ICD-10 calls it "depersonalization-derealization syndrome" and classifies it as a neurotic disorder. Although the disorder is an alteration in the subjective experience of reality, it is not a form of psychosis, as the person is able to distinguish between their own internal experiences and the objective reality of the outside world. During episodic and continuous depersonalization, the person can distinguish between reality and fantasy and the grasp on reality remains stable at all times. While depersonalization-derealization disorder was once considered rare, lifetime experiences with it occur in about 1–2% of the general population. The chronic form of the disorder has a reported prevalence of 0.8 to 1.9%. While brief episodes of depersonalization or derealization can be common in the general population, the disorder is only diagnosed when these symptoms cause substantial distress or impair social, occupational, or other important areas of functioning.

interpersonal trauma derealization depersonalization-derealization

References

  1. Radovic F (2002). Feelings of Unreality: A Conceptual and Phenomenological Analysis of the Language of Depersonalization. Philosophy, Psychiatry, & Psychology. pp. 9: 271–279. http://muse.jhu.edu/journals/philosophy_psychiatry_and_psychology/v009/9.3radovic01.html. 
  2. Sierra, Mauricio; Medford, Nick; Wyatt, Geddes; David, Anthony S. (1 May 2012). "Depersonalization disorder and anxiety: A special relationship?". Psychiatry Research 197 (1–2): 123–127. doi:10.1016/j.psychres.2011.12.017. PMID 22414660.  https://dx.doi.org/10.1016%2Fj.psychres.2011.12.017
  3. Sierra, Mauricio (2009) (in en). Depersonalization: A New Look at a Neglected Syndrome. Cambridge University Press. p. 1. ISBN 9781139489423. https://books.google.com/books?id=qOat1nDGZAkC&lpg=PP1&dq=Depersonalization%20Disorder&pg=PA1. 
  4. Simeon D (2004). "Depersonalisation Disorder: A Contemporary Overview". CNS Drugs 18 (6): 343–354. doi:10.2165/00023210-200418060-00002. PMID 15089102.  https://dx.doi.org/10.2165%2F00023210-200418060-00002
  5. "Feeling unreal: a depersonalization disorder update of 117 cases". Journal of Clinical Psychiatry 64 (9): 990–7. 2003. doi:10.4088/JCP.v64n0903. PMID 14628973.  https://dx.doi.org/10.4088%2FJCP.v64n0903
  6. "Depersonalisation disorder: clinical features of 204 cases". The British Journal of Psychiatry 182 (5): 428–33. May 2003. doi:10.1192/bjp.182.5.428. PMID 12724246.  https://dx.doi.org/10.1192%2Fbjp.182.5.428
  7. Blevins, Christy A.; Weathers, Frank W.; Mason, Elizabeth A. (1 October 2012). "Construct Validity of Three Depersonalization Measures in Trauma-Exposed College Students". Journal of Trauma & Dissociation 13 (5): 539–553. doi:10.1080/15299732.2012.678470. PMID 22989242.  https://dx.doi.org/10.1080%2F15299732.2012.678470
  8. Sacco, Robert G. (December 2010). "The Circumplex Structure of Depersonalization/Derealization". International Journal of Psychological Studies 2 (2): 26–40. doi:10.5539/ijps.v2n2p26.  https://dx.doi.org/10.5539%2Fijps.v2n2p26
  9. Daphne Simeon; Jeffrey Abugel (7 November 2008). Feeling Unreal: Depersonalization Disorder and the Loss of the Self. Oxford University Press. p. 3. ISBN 978-0-19-976635-2. https://books.google.com/books?id=ONLyq-mVLuIC&pg=PA3. 
  10. "Symptoms and causes - Mayo Clinic". https://www.mayoclinic.org/diseases-conditions/depersonalization-derealization-disorder/symptoms-causes/syc-20352911?p=1. 
  11. "The role of childhood interpersonal trauma in depersonalization disorder". The American Journal of Psychiatry 158 (7): 1027–33. 2001. doi:10.1176/appi.ajp.158.7.1027. PMID 11431223.  https://dx.doi.org/10.1176%2Fappi.ajp.158.7.1027
  12. Simeon D: Depersonalisation disorder: a contemporary overview . CNS Drugs. 2004. https://www.neurotransmitter.net/depersonalization.html
  13. "Depersonalization and individualism: the effect of culture on symptom profiles in panic disorder". J. Nerv. Ment. Dis. 195 (12): 989–95. December 2007. doi:10.1097/NMD.0b013e31815c19f7. PMID 18091192.  https://dx.doi.org/10.1097%2FNMD.0b013e31815c19f7
  14. "Depersonalisation disorder: a cognitive-behavioural conceptualisation". Behav Res Ther 41 (12): 1451–67. December 2003. doi:10.1016/S0005-7967(03)00066-4. PMID 14583413.  https://dx.doi.org/10.1016%2FS0005-7967%2803%2900066-4
  15. "Understanding and treating depersonalisation disorder". Advances in Psychiatric Treatment 11 (2): 92–100. 2005. doi:10.1192/apt.11.2.92. Archived from the original on 16 July 2011. https://web.archive.org/web/20110716095835/http://apt.rcpsych.org/cgi/content/full/11/2/92#SEC5. 
  16. "Feeling unreal: a PET study of depersonalization disorder". The American Journal of Psychiatry 157 (11): 1782–8. November 2000. doi:10.1176/appi.ajp.157.11.1782. PMID 11058475.  https://dx.doi.org/10.1176%2Fappi.ajp.157.11.1782
  17. "Depersonalization disorder: thinking without feeling". Psychiatry Research: Neuroimaging 108 (3): 145–160. 2001. doi:10.1016/S0925-4927(01)00119-6. PMID 11756013.  https://dx.doi.org/10.1016%2FS0925-4927%2801%2900119-6
  18. "Emotional memory in depersonalization disorder: A functional MRI study". Psychiatry Research: Neuroimaging 148 (2–3): 93–102. December 2006. doi:10.1016/j.pscychresns.2006.05.007. PMID 17085021. Archived from the original on 26 September 2007. https://web.archive.org/web/20070926115431/http://www-bmu.psychiatry.cam.ac.uk/publications/medford06emo.pdf. 
  19. "Autonomic response in depersonalization disorder". Archives of General Psychiatry 59 (9): 833–8. September 2002. doi:10.1001/archpsyc.59.9.833. PMID 12215083.  https://dx.doi.org/10.1001%2Farchpsyc.59.9.833
  20. "Hypothalamic-pituitary-adrenal axis dysregulation in depersonalization disorder". Neuropsychopharmacology 25 (5): 793–5. 2001. doi:10.1016/S0893-133X(01)00288-3. PMID 11682263.  https://dx.doi.org/10.1016%2FS0893-133X%2801%2900288-3
  21. "Basal activity of the hypothalamic-pituitary-adrenal axis in patients with depersonalization disorder". Psychiatry Research 104 (1): 85–9. 2001. doi:10.1016/S0165-1781(01)00291-8. PMID 11600192.  https://dx.doi.org/10.1016%2FS0165-1781%2801%2900291-8
  22. Strohle, A.; Kumpfel, T.; Sonntag, A. (2000). "Paroxetine for Depersonalization Associated With Multiple Sclerosis". Am. J. Psychiatry 157 (1): 150. doi:10.1176/ajp.157.1.150. PMID 10618046.  https://dx.doi.org/10.1176%2Fajp.157.1.150
  23. "Symptoms and causes - Mayo Clinic". https://www.mayoclinic.org/diseases-conditions/dissociative-disorders/symptoms-causes/syc-20355215?p=1. 
  24. Depersonalization Disorder, (DSM-IV 300.6, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) https://archive.is/20121209121421/http://www.psychiatryonline.com/content.aspx?aID=9816
  25. Steinberg M: Interviewers Guide to the Structured Clinical Interview for DSM-IV Dissociative Disorders (SCID-D) . Washington, DC, American Psychiatric Press, 1994. http://www.appi.org/set.cfm?id=8862
  26. "Development, reliability, and validity of a dissociation scale". J. Nerv. Ment. Dis. 174 (12): 727–35. 1986. doi:10.1097/00005053-198612000-00004. PMID 3783140.  https://dx.doi.org/10.1097%2F00005053-198612000-00004
  27. Simeon and Abugel p. 73-4
  28. "Dissociative disorders in psychiatric inpatients". Am J Psychiatry 150 (7): 1037–42. July 1993. doi:10.1176/ajp.150.7.1037. PMID 8317573.  https://dx.doi.org/10.1176%2Fajp.150.7.1037
  29. Sugiura, Miyuki; Hirosawa, Masataka; Tanaka, Sumio; Nishi, Yasunobu; Yamada, Yasuyuki; Mizuno, Motoki (1 June 2009). "Reliability and validity of a Japanese version of the Cambridge depersonalization scale as a screening instrument for depersonalization disorder". Psychiatry and Clinical Neurosciences 63 (3): 314–321. doi:10.1111/j.1440-1819.2009.01939.x. PMID 19566762.  https://dx.doi.org/10.1111%2Fj.1440-1819.2009.01939.x
  30. "Archived copy". Archived from the original on 18 June 2016. https://web.archive.org/web/20160618131606/http://www.who.int/classifications/icd/en/GRNBOOK.pdf. Retrieved 2017-03-27. 
  31. Hunter, Elaine C. M.; Charlton, Jane; David, Anthony S. (2017). "Depersonalisation and derealisation: assessment and management". BMJ 356: j745. doi:10.1136/bmj.j745. PMID 28336554.  https://dx.doi.org/10.1136%2Fbmj.j745
  32. "Understanding and treating depersonalization disorder". Advances in Psychiatric Treatment 11 (5): 92–100. 2005. doi:10.1192/apt.11.2.92.  https://dx.doi.org/10.1192%2Fapt.11.2.92
  33. "Cognitive-behaviour therapy for depersonalisation disorder: an open study". Behav Res Ther 43 (9): 1121–30. September 2005. doi:10.1016/j.brat.2004.08.003. PMID 16005701.  https://dx.doi.org/10.1016%2Fj.brat.2004.08.003
  34. Bar, E., & Minnen van, A. (2011). Protocollaire behandeling van de depersonalisatiestoornis. In: G.P.J. Keijsers, A.van Minnen, & C.A.L. Hoogduin (red.). Protocollaire behandelingen voor volwassenen met psychische klachten. Arnhem, Boom Cure & Care publishers.
  35. Sierra, M (January 2008). "Depersonalization disorder: pharmacological approaches.". Expert Review of Neurotherapeutics 8 (1): 19–26. doi:10.1586/14737175.8.1.19. PMID 18088198.  https://dx.doi.org/10.1586%2F14737175.8.1.19
  36. null
  37. Perez, David L.; Matin, Nassim; Williams, Benjamin; Tanev, Kaloyan; Makris, Nikos; LaFrance, W. Curt; Dickerson, Bradford C. (January 2018). "Cortical Thickness Alterations Linked to Somatoform and Psychological Dissociation in Functional Neurological Disorders". Human Brain Mapping 39 (1): 428–439. doi:10.1002/hbm.23853. ISSN 1065-9471. PMID 29080235.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5747307
  38. Sierra M (2008). "Depersonalization disorder: pharmacological approaches". Expert Rev Neurother 8 (1): 19–26. doi:10.1586/14737175.8.1.19. PMID 18088198.  https://dx.doi.org/10.1586%2F14737175.8.1.19
  39. Mauricio Sierra (13 August 2009). Depersonalization: A New Look at a Neglected Syndrome. Cambridge, UK: Cambridge University Press. pp. 120. ISBN 978-0-521-87498-4. https://books.google.com/?id=qOat1nDGZAkC. 
  40. Ross CA (1991). "Epidemiology of multiple personality disorder and dissociation". Psychiatric Clinics of North America 14 (3): 503–17. doi:10.1016/S0193-953X(18)30286-7. PMID 1946021.  https://dx.doi.org/10.1016%2FS0193-953X%2818%2930286-7
  41. "Chronic depersonalization following illicit drug use: a controlled analysis of 40 cases". Addiction 98 (12): 1731–6. December 2003. doi:10.1111/j.1360-0443.2003.00548.x. PMID 14651505.  https://dx.doi.org/10.1111%2Fj.1360-0443.2003.00548.x
  42. Henri Frédéric Amiel's The Journal Intime Retrieved June 2, 2007 http://www.gutenberg.org/dirs/etext05/8ajrn10.txt
  43. "Depersonalization: a conceptual history". Hist Psychiatry 8 (30 Pt 2): 213–29. June 1997. doi:10.1177/0957154X9700803002. PMID 11619439.  https://dx.doi.org/10.1177%2F0957154X9700803002
  44. Mayer-Gross W. (1935). "On depersonalization." British Journal of Medicine and Psychology (15)103–126.
  45. Simeon and Abugel p. 12 & 58
  46. Sogomy, Varga (June 2012). "Depersonalization and the Sense of Realness". Philosophy, Psychiatry, & Psychology 19 (2). 
  47. Simeon, D; Abugel J (2006). "The Blow of the Void: Depersonalization in Literature and Philosophy". Feeling unreal: depersonalization disorder and the loss of the self. United States: Oxford University Press. pp. 127–58. ISBN 978-0-19-517022-1.  https://books.google.com/?id=M–Cgs_T7Cl8C&pg=PA127#v=onepage&q&f=false
  48. Hirshberg, Glen (2003). The Snowman's Children: A Novel. New York, NY: Carroll & Graf. ISBN 978-0-7867-1253-3. https://archive.org/details/snowmanschildren00hirs. 
  49. Suzanne Segal (1996). Collision With the Infinite: A Life Beyond the Personal Self. Blue Dove Press. ISBN 978-1-884997-27-3. https://archive.org/details/collisionwithinf00sega. 
  50. "A Lesson in Humility from Adam Duritz". September 30, 2014. Archived from the original on 22 April 2016. https://web.archive.org/web/20160422165615/http://www.menshealth.com/guy-wisdom/adam-duritz-interview. 
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