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HandWiki. Glucosepane. Encyclopedia. Available online: https://encyclopedia.pub/entry/35914 (accessed on 25 September 2026).
HandWiki. Glucosepane. Encyclopedia. Available at: https://encyclopedia.pub/entry/35914. Accessed September 25, 2026.
HandWiki. "Glucosepane" Encyclopedia, https://encyclopedia.pub/entry/35914 (accessed September 25, 2026).
HandWiki. (2022, November 23). Glucosepane. In Encyclopedia. https://encyclopedia.pub/entry/35914
HandWiki. "Glucosepane." Encyclopedia. Web. 23 November, 2022.
Glucosepane
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The content is sourced from: https://handwiki.org/wiki/Chemistry:Glucosepane

Glucosepane is a lysine-arginine protein cross-linking product and advanced glycation end product (AGE) derived from D-glucose. It is an irreversible, covalent cross-link product that has been found to make intermolecular and intramolecular cross-links in the collagen of the extracellular matrix (ECM) and crystallin of the eyes. Covalent protein cross-links irreversibly link proteins together in the ECM of tissues. Glucosepane is present in human tissues at levels 10 to 1000 times higher than any other cross-linking AGE, and is currently considered to be the most important cross-linking AGE.

advanced glycation collagen intermolecular

References

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