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HandWiki. 6-Formylindolo(3,2-b)carbazole. Encyclopedia. Available online: https://encyclopedia.pub/entry/34862 (accessed on 03 October 2026).
HandWiki. 6-Formylindolo(3,2-b)carbazole. Encyclopedia. Available at: https://encyclopedia.pub/entry/34862. Accessed October 03, 2026.
HandWiki. "6-Formylindolo(3,2-b)carbazole" Encyclopedia, https://encyclopedia.pub/entry/34862 (accessed October 03, 2026).
HandWiki. (2022, November 16). 6-Formylindolo(3,2-b)carbazole. In Encyclopedia. https://encyclopedia.pub/entry/34862
HandWiki. "6-Formylindolo(3,2-b)carbazole." Encyclopedia. Web. 16 November, 2022.
6-Formylindolo(3,2-b)carbazole
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6-Formylindolo[3,2-b]carbazole (FICZ) is a chemical compound with the molecular formula C19H12N2O. It is a nitrogen heterocycle, having an extremely high affinity (Kd = 7 x 10−11M) for binding to the aryl hydrocarbon receptor (AHR). It was originally identified as a photooxidized derivative of the amino acid tryptophan and suggested to be the endogenous ligand of the AHR. Later, also enzymatic formation of FICZ was shown.

6-formylindolo32-bcarbazole heterocycle aryl

References

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