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HandWiki. Ischemia. Encyclopedia. Available online: https://encyclopedia.pub/entry/34343 (accessed on 25 September 2026).
HandWiki. Ischemia. Encyclopedia. Available at: https://encyclopedia.pub/entry/34343. Accessed September 25, 2026.
HandWiki. "Ischemia" Encyclopedia, https://encyclopedia.pub/entry/34343 (accessed September 25, 2026).
HandWiki. (2022, November 14). Ischemia. In Encyclopedia. https://encyclopedia.pub/entry/34343
HandWiki. "Ischemia." Encyclopedia. Web. 14 November, 2022.
Ischemia
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The content is sourced from: https://handwiki.org/wiki/Medicine:Ischemia

Ischemia or ischaemia is a restriction in blood supply to any tissues, muscle group, or organ of the body, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive). Ischemia is generally caused by problems with blood vessels, with resultant damage to or dysfunction of tissue i.e. hypoxia and microvascular dysfunction. It also means local hypoxia in a given part of a body sometimes resulting from constriction (such as vasoconstriction, thrombosis or embolism). Ischemia comprises not only insufficiency of oxygen, but also reduced availability of nutrients and inadequate removal of metabolic wastes. Ischemia can be partial (poor perfusion) or total blockage. The inadequate delivery of oxygenated blood to the organs must be resolved either by treating the cause of the inadequate delivery or reducing the oxygen demand of the system that needs it. For example, patients with myocardial ischemia have a decreased blood flow to the heart and are prescribed with medications that reduce chronotrophy and ionotrophy to meet the new level of blood delivery supplied by the stenosed so that it is adequate.

cellular metabolism myocardial ischemia blood flow

References

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  21. O'Brien, Emily C.; Greiner, Melissa A.; Xian, Ying; Fonarow, Gregg C.; Olson, DaiWai M.; Schwamm, Lee H.; Bhatt, Deepak L.; Smith, Eric E. et al. (2015-10-13). "Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study" (in en). Circulation 132 (15): 1404–1413. doi:10.1161/CIRCULATIONAHA.115.016183. ISSN 0009-7322. PMID 26246175.  https://dx.doi.org/10.1161%2FCIRCULATIONAHA.115.016183
  22. Infarct Combat Project website; accessed October 26, 2015. http://www.infarctcombat.org
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