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HandWiki. Bradykinin. Encyclopedia. Available online: https://encyclopedia.pub/entry/32958 (accessed on 24 September 2026).
HandWiki. Bradykinin. Encyclopedia. Available at: https://encyclopedia.pub/entry/32958. Accessed September 24, 2026.
HandWiki. "Bradykinin" Encyclopedia, https://encyclopedia.pub/entry/32958 (accessed September 24, 2026).
HandWiki. (2022, November 04). Bradykinin. In Encyclopedia. https://encyclopedia.pub/entry/32958
HandWiki. "Bradykinin." Encyclopedia. Web. 04 November, 2022.
Bradykinin
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The content is sourced from: https://handwiki.org/wiki/Chemistry:Bradykinin

Bradykinin (BK) (Greek brady-, slow; -kinin, kīn(eîn) to move) is a peptide that promotes inflammation. It causes arterioles to dilate (enlarge) via the release of prostacyclin, nitric oxide, and endothelium-derived hyperpolarizing factor and makes veins constrict, via prostaglandin F2, thereby leading to leakage into capillary beds, due to the increased pressure in the capillaries. Bradykinin is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids. A class of drugs called angiotensin converting enzyme inhibitors (ACE inhibitors) increase bradykinin levels by inhibiting its degradation, thereby increasing its blood pressure lowering effect. ACE inhibitors are FDA approved for the treatment of hypertension and heart failure.

arterioles inflammation prostaglandin

References

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