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HandWiki. Alteplase. Encyclopedia. Available online: https://encyclopedia.pub/entry/32033 (accessed on 24 September 2026).
HandWiki. Alteplase. Encyclopedia. Available at: https://encyclopedia.pub/entry/32033. Accessed September 24, 2026.
HandWiki. "Alteplase" Encyclopedia, https://encyclopedia.pub/entry/32033 (accessed September 24, 2026).
HandWiki. (2022, October 31). Alteplase. In Encyclopedia. https://encyclopedia.pub/entry/32033
HandWiki. "Alteplase." Encyclopedia. Web. 31 October, 2022.
Alteplase
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The content is sourced from: https://handwiki.org/wiki/Chemistry:Alteplase

Alteplase (t-PA), a biosynthetic form of human tissue-type plasminogen activator (t-PA), is a thrombolytic medication, used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. It is given by injection into a vein or artery. Alteplase is the same as the normal human plasminogen activator produced in vascular endothelial cells and is synthesized via recombinant DNA technology in Chinese hamster ovary cells (CHO). Alteplase causes the breakdown of a clot by inducing fibrinolysis.

alteplase pulmonary embolism human plasminogen

References

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