| Version | Summary | Created by | Modification | Content Size | Created at | Operation |
|---|---|---|---|---|---|---|
| 1 | Vivi Li | -- | 1063 | 2022-10-31 01:32:54 |
Left-right asymmetry (LR asymmetry) refers to differences in structure (symmetry breaking) across the mediolateral (left and right) plane in animals. This plane is defined with respect to the anteroposterior and dorsoventral axes and is perpendicular to both. Because the left-right plane is not strictly an axis (as it is not established through a morphogen gradient), to create asymmetry, the left and right sides need to be patterned separately. LR asymmetry is pervasive throughout metazoans and present throughout every major lineage. Notable examples include the large and small claws of the fiddler crab, the left offset of the vertebrate heart, asymmetrical gut coiling in Drosophila melanogaster, and dextral (clockwise) and sinistral (counterclockwise) coiling of gastropods. This asymmetry can be restricted to a specific organ or feature, as in the crab claws, or be expressed throughout the entire body as in snails.