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HandWiki. Protease Inhibitor. Encyclopedia. Available online: https://encyclopedia.pub/entry/31278 (accessed on 25 September 2026).
HandWiki. Protease Inhibitor. Encyclopedia. Available at: https://encyclopedia.pub/entry/31278. Accessed September 25, 2026.
HandWiki. "Protease Inhibitor" Encyclopedia, https://encyclopedia.pub/entry/31278 (accessed September 25, 2026).
HandWiki. (2022, October 26). Protease Inhibitor. In Encyclopedia. https://encyclopedia.pub/entry/31278
HandWiki. "Protease Inhibitor." Encyclopedia. Web. 26 October, 2022.
Protease Inhibitor
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The content is sourced from: https://handwiki.org/wiki/Biology:Protease_inhibitor

In biology and biochemistry, protease inhibitors, or antiproteases, are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins). Many naturally occurring protease inhibitors are proteins. In medicine, protease inhibitor is often used interchangeably with alpha 1-antitrypsin (A1AT, which is abbreviated PI for this reason). A1AT is indeed the protease inhibitor most often involved in disease, namely in alpha-1 antitrypsin deficiency.

alpha-1 antitrypsin protease inhibitor protease inhibitors

References

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  11. Figueiredo da Silva AA; de Carvalho Vieira L; Krieger MA; Goldenberg S; Zanchin NI; Guimarães BG (February 2007). "Crystal structure of chagasin, the endogenous cysteine-protease inhibitor from Trypanosoma cruzi". J. Struct. Biol. 157 (2): 416–23. doi:10.1016/j.jsb.2006.07.017. PMID 17011790.  https://dx.doi.org/10.1016%2Fj.jsb.2006.07.017
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