Video Upload Options

References

1. "Nitroglycerin". The American Society of Health-System Pharmacists. Archived from the original on 21 December 2016. https://web.archive.org/web/20161221004220/https://www.drugs.com/monograph/nitroglycerin.html. Retrieved 8 December 2016. 
2. "Coronary artery spasm--clinical features, diagnosis, pathogenesis, and treatment". J Cardiol 51 (1): 2–17. February 2008. doi:10.1016/j.jjcc.2008.01.001. PMID 18522770. http://www.journal-of-cardiology.com/article/S0914-5087(08)00002-6/fulltext. Retrieved 23 November 2016. 
3. "Nitro-Dur - FDA prescribing information, side effects and uses". drugs.com. Archived from the original on 1 April 2017. https://web.archive.org/web/20170401055025/https://www.drugs.com/pro/nitro-dur.html. Retrieved 31 March 2017. 
4. Goldin, M; Malanga, GA (September 2013). "Tendinopathy: a review of the pathophysiology and evidence for treatment.". The Physician and Sportsmedicine 41 (3): 36–49. doi:10.3810/psm.2013.09.2019. PMID 24113701.  https://dx.doi.org/10.3810%2Fpsm.2013.09.2019
5. Andres, BM; Murrell, GA (2008). "Treatment of Tendinopathy: What Works, What Does Not, and What is on the Horizon". Clin. Orthop. Relat. Res. 466 (7): 1539–54. doi:10.1007/s11999-008-0260-1. PMID 18446422.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2505250
6. Assem, Yusuf; Arora, Manit (1 January 2015). "Glyceryl trinitrate patches—An alternative treatment for shoulder impingement syndrome". Journal of Orthopaedic Translation 3 (1): 12–20. doi:10.1016/j.jot.2014.11.001. http://www.sciencedirect.com/science/article/pii/S2214031X1400254X. Retrieved 31 March 2017. 
7. Bokhari, Ali R.; Murrell, George A. C. (1 February 2012). "The role of nitric oxide in tendon healing". Journal of Shoulder and Elbow Surgery 21 (2): 238–244. doi:10.1016/j.jse.2011.11.001. http://www.sciencedirect.com/science/article/pii/S105827461100560X. Retrieved 31 March 2017. 
8. Gambito, ED; Gonzalez-Suarez, CB; Oquiñena, TI; Agbayani, RB (2010). "Evidence on the effectiveness of topical nitroglycerin in the treatment of tendinopathies: a systematic review and meta-analysis. syndrome". Arch Phys Med Rehabil 91: 1291–305. doi:10.1016/j.apmr.2010.02.008. PMID 20684913.  https://dx.doi.org/10.1016%2Fj.apmr.2010.02.008
9. "Anal Fissure Symptoms, Treatment, Causes". medicinenet.com. Archived from the original on 1 May 2017. https://web.archive.org/web/20170501232309/http://www.medicinenet.com/anal_fissure/page3.htm. Retrieved 31 March 2017. 
10. Fenton, Caroline; Wellington, Keri; Easthope, Stephanie E. (2006). "0.4% nitroglycerin ointment : in the treatment of chronic anal fissure pain". Drugs 66 (3): 343–349. doi:10.2165/00003495-200666030-00006. ISSN 0012-6667. PMID 16526822.  https://dx.doi.org/10.2165%2F00003495-200666030-00006
11. Nakamura et al.
12. Gori et al.
13. Such activation is suggested to cause sympathetic activation, and release of vasoconstrictors such as endothelin and angiotensin II.
14. Hypothesis of Munzel et al. (1995).
15. "Phosphodiesterase Inhibitors". CV Pharmacology. Archived from the original on 13 June 2017. https://web.archive.org/web/20170613122156/http://cvpharmacology.com/vasodilator/PDEI. Retrieved 3 April 2017. 
16. Scientific Committee on Occupational Exposure Limits (May 2008). Recommendation From the Scientific Committee on Occupational Exposure Limits for Glycerol Trinitrate (Nitroglycerin) [SCOEL/SUM/147] (Report). The Hague, NDL: Sociaal-Economische Raad. Archived from the original on 3 March 2016. http://www.ser.nl/nl/grenswaarden/~/media/Files/Internet/Grenswaarden/SCOEL/GSW524_SCOEL_Prov147Nitroglycerine.ashx. Retrieved 30 March 2017. 
17. Liddle, R.; Richmond, W. (1998). "Investigation into voltage breakdown in glyceryl trinitrate patches". Resuscitation 37 (3): 145–148. doi:10.1016/S0300-9572(98)00059-8. PMID 9715773.  https://dx.doi.org/10.1016%2FS0300-9572%2898%2900059-8
18. Sobrero, Ascagne (1847). "Sur plusieur composés détonants produits avec l'acide nitrique et le sucre, la dextrine, la lactine, la mannite et la glycérine" (in French). Comptes rendus 24: 247–248. https://babel.hathitrust.org/cgi/pt?id=mdp.39015035450777;view=1up;seq=259.  From p. 248: "Il faut toutefois être sur ses gardes en faissant cet essai, car il suffit d'en tenir une très-petite quantité (ce qu'on peut en prendre en y mouillant légèrement le bout du petit doigt) sur la langue pour en éprouver une migraine assez forte pendant pleusieurs heures. Cette action sur le corps humain a été constatée par plusieurs personnes dans mon laboratoire, et je l'ai éprouvée plusieurs fois sur moi-même avant que je fusse certain qu'elle a des propriétés toxiques." (It is always necessary to be on one's guard when making this test, for it suffices to take a very small quantity of it (which one can take by lightly wetting, in it, the tip of the little finger) on [one's] tongue in order to feel a quite strong headache for several hours. This action on the human body has been confirmed by several persons in my laboratory, and I tested it several times on myself before I was certain that it has toxic properties.)
19. Sobrero, Ascanio (1849). "Sopra alcuni nuovi composti fulminanti ottenuti col mezzo dell’azione dell’acido nitrico sulle sostante organiche vegetali" (in Italian). Memorie della Reale Accademia delle Scienze di Torino. 2nd series 10: 195–201. https://babel.hathitrust.org/cgi/pt?id=iau.31858045931643;view=1up;seq=281.  From p. 198: " … basta il tenere una gocciolina di Piroglicerina sulla lingua, senza inghiottirla, perchè si provi tosto un violento dolore di capo, quale è quello di una forte emicrania, accompagnato da pulsazioni interne assai penose: nello stesso tempo provasi debolezza alle estremità inferiori. Questo effetto sentii io più volte, ed il provarono il signor prof. Valerico Cauda prepartore della mia scuola, ed altre persone ehe tentarono l'esperimento." ( … it suffices to hold a droplet of Piroglicerina [i.e., Sabrero's name for nitroglycerin] on [one's] tongue, without swallowing it, because one soon feels a violent pain in the head, which is a strong headache, accompanied by very painful internal throbbings; at the same time one would feel weakness in the lower extremities. This effect I felt many times, and it was felt by Prof. Valerico Cauda, who prepares lecture demonstrations at my school, and [by] other people who tried the experiment.)
20. (Sobrero, 1849), pp. 198–199. On pages 198–199, Sobrero describes the results of administering nitroglycerin to a puppy, a mouse, and a guinea pig. After giving (orally) several centigrams of nitroglycerin to a puppy, the animal vomited, and within 7-8 minutes, it ceased to breath. Sobrero managed to revive it, but it convulsed. "L'apertura del suo corpo non diede a scorgere alterazione veruna al ventricolo. I vasi de cervello erano pieni di sangue, come rigonfii di sangue erano l'orocchietta destra de cuore e specialmente la vena cava superiore." (The opening of its body did not reveal any deterioration of the ventricle. The vessels of the brain were full of blood; similarly swollen with blood were the right auricle of the heart and especially the superior vena cava.) Administering nitroglycerin to a mouse and a guinea pig produced similar results.
21. Hering, Constantine (1849). "Glonoine, a new medicine for headache, &c.". American Journal of Homoeopathy 4 (1): 3–5. https://babel.hathitrust.org/cgi/pt?id=mdp.39015009544423;view=1up;seq=171.  Note: Hering renamed nitroglycerine "glonoine".
22. Fye, W. Bruce (January 1986). "Nitroglycerin: a homeopathic remedy". Circulation 73 (1): 21–29. doi:10.1161/01.cir.73.1.21. http://circ.ahajournals.org/content/circulationaha/73/1/21.full.pdf.  See pp. 22–23.
23. Murrell, William (1879). "Nitro-glycerine as a remedy for angina pectoris.". The Lancet: 80–81, 113–115, 151–152, 225–227. doi:10.1016/s0140-6736(02)42404-x. https://babel.hathitrust.org/cgi/pt?id=uc1.d0000772988;view=1up;seq=78. 
24. Sneader, Walter (2005). Drug Discovery: A History. New York, NY: John Wiley & Sons. p. 433. ISBN 0471899801. https://books.google.com/books?id=mYQxRY9umjcC. 
25. Kaplan, KJ; Taber, M; Teagarden, JR; Parker, M; Davison, R (1985). "Association of methemoglobinemia and intravenous nitroglycerin administration". Am J Cardiol 55: 181–3. doi:10.1016/0002-9149(85)90324-8. PMID 3917597.  https://dx.doi.org/10.1016%2F0002-9149%2885%2990324-8