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HandWiki. Substance Use Disorder. Encyclopedia. Available online: https://encyclopedia.pub/entry/29035 (accessed on 23 September 2026).
HandWiki. Substance Use Disorder. Encyclopedia. Available at: https://encyclopedia.pub/entry/29035. Accessed September 23, 2026.
HandWiki. "Substance Use Disorder" Encyclopedia, https://encyclopedia.pub/entry/29035 (accessed September 23, 2026).
HandWiki. (2022, October 12). Substance Use Disorder. In Encyclopedia. https://encyclopedia.pub/entry/29035
HandWiki. "Substance Use Disorder." Encyclopedia. Web. 12 October, 2022.
Substance Use Disorder
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Substance use disorder (SUD) is the persistent use of drugs (including alcohol) despite substantial harm and adverse consequences. Substance use disorders are characterized by an array of mental/emotional, physical, and behavioral problems such as chronic guilt; an inability to reduce or stop consuming the substance(s) despite repeated attempts; driving while intoxicated; and physiological withdrawal symptoms. Drug classes that are involved in SUD include: alcohol; cannabis; phencyclidine and other hallucinogens, such as arylcyclohexylamines; inhalants; opioids; sedatives, hypnotics, or anxiolytics; stimulants; tobacco; and other or unknown substances. In the Diagnostic and Statistical Manual of Mental Disorders 5th edition (2013), also known as DSM-5, the DSM-IV diagnoses of substance abuse and substance dependence were merged into the category of substance use disorders. The severity of substance use disorders can vary widely; in the DSM-5 diagnosis of a SUD, the severity of an individual's SUD is qualified as mild, moderate, or severe on the basis of how many of the 11 diagnostic criteria are met. The International Classification of Diseases 11th revision (ICD-11) divides substance use disorders into two categories: (1) harmful pattern of substance use; and (2) substance dependence. In 2017, globally 271 million people (5.5% of adults) were estimated to have used one or more illicit drugs. Of these, 35 million had a substance use disorder. An additional 237 million men and 46 million women have alcohol use disorder as of 2016. In 2017, substance use disorders from illicit substances directly resulted in 585,000 deaths. Direct deaths from drug use, other than alcohol, have increased over 60 percent from 2000 to 2015. Alcohol use resulted in an additional 3 million deaths in 2016.

arylcyclohexylamines alcohol use disorder substance use disorders

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