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HandWiki. Type A Influenza Vaccine. Encyclopedia. Available online: https://encyclopedia.pub/entry/28850 (accessed on 26 September 2026).
HandWiki. Type A Influenza Vaccine. Encyclopedia. Available at: https://encyclopedia.pub/entry/28850. Accessed September 26, 2026.
HandWiki. "Type A Influenza Vaccine" Encyclopedia, https://encyclopedia.pub/entry/28850 (accessed September 26, 2026).
HandWiki. (2022, October 11). Type A Influenza Vaccine. In Encyclopedia. https://encyclopedia.pub/entry/28850
HandWiki. "Type A Influenza Vaccine." Encyclopedia. Web. 11 October, 2022.
Type A Influenza Vaccine
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The content is sourced from: https://handwiki.org/wiki/Medicine:Type_A_influenza_vaccine

Type A influenza vaccine is for the prevention of infection of influenza A virus and also the influenza-related complications. Different monovalent type A influenza vaccines have been developed for different subtypes of influenza A virus including H1N1 and H5N1. Both intramuscular injection or intranasal spray are available on market. Unlike the seasonal influenza vaccines which are used annually, they are usually used during the outbreak of certain strand of subtypes of influenza A. Common adverse effects includes injection site reaction and local tenderness. Incidences of headache and myalgia were also reported with H1N1 whereas cases of fever has also been demonstrated with H5N1 vaccines. It is stated that immunosuppressant therapies would reduce the therapeutic effects of vaccines and that people with egg allergy should go for the egg-free preparations. There are different methods in developing the vaccines. Traditionally, inactivated viral vaccine and live attenuated virus vaccine have been approved. Inactivated viral vaccine is primary used parentally and the live attenuated vaccine is used intranasally. Development of new technologies including the recombinant hemagglutinin technology have widely been studied. Influenza A virus was successfully identified and isolated by Wilson Smith, Christopher Andrewes, and Patrick Laidlaw in the 1930s and the first inactivated monovalent influenza A vaccine was made after a decade. The first H5N1 vaccine was approved in 2007. It was intentionally developed to prepare for the possible H5N1 outbreak in the future. Moreover, in view of the H1N1 outbreak in 2009, H1N1 monovalent vaccines, targeting only H1N1 virus, was produced. Influenza A exists in many subtypes including H5N1, H1N1 and H3N2. Different formulations of monovalent vaccines have been developed over the years to cater different needs and antigens identified.

seasonal influenza intramuscular injection live attenuated vaccine

References

  1. "Use of Influenza A (H1N1) 2009 Monovalent Vaccine". https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5810a1.htm. 
  2. "Influenza Vaccine for 2021-2022". The Medical Letter Issue 1634. 2021-10-04. https://secure-medicalletter-org.eproxy.lib.hku.hk/w1634a. 
  3. Ploske, Greg L. (2012-01-06). "A/H5N1 Prepandemic Influenza Vaccine (Whole Virion, Vero Cell-Derived, Inactivated) [Vepacel®"]. Pubmed 72 (11): 1543–1557. doi:10.2165/11209650-000000000-00000. PMID 22788239. https://dx.doi.org/10.2165/11209650-000000000-00000. 
  4. M Imai , S Herfst, E M Sorrell, E J A Schrauwen, M Linster, M De Graaf, R A M Fouchier, Y Kawaoka (2013-08-13). "Transmission of influenza A/H5N1 viruses in mammals". PubMed 178 (1): 15–20. doi:10.1016/j.virusres.2013.07.017. PMID 23954580. PMC 3838911. https://dx.doi.org/10.1016/j.virusres.2013.07.017. 
  5. Jiang-Tao Lin , Chang-Gui Li, Xu Wang, Nan Su, Yan Liu, Yuan-Zheng Qiu, Meng Yang, Jiang-Ting Chen, Han-Hua Fang, Xiao-Ping Dong, Wei-Dong Yin, Zi-Jian Feng (2009-01-15). "Antibody persistence after 2-dose priming and booster response to a third dose of an inactivated, adjuvanted, whole-virion H5N1 vaccine". PubMed. https://pubmed-ncbi-nlm-nih-gov.eproxy.lib.hku.hk/19067606/. 
  6. Research, Center for Biologics Evaluation and (2019-05-14). "Influenza A (H1N1) 2009 Monovalent" (in en). FDA. https://www.fda.gov/vaccines-blood-biologics/vaccines/influenza-h1n1-2009-monovalent. 
  7. "CDC H1N1 Flu | Questions & Answers Novel H1N1 Influenza Vaccine". https://www.cdc.gov/h1n1flu/vaccination/public/vaccination_qa_pub.htm. 
  8. "CDC H1N1 Flu | Questions & Answers Novel H1N1 Influenza Vaccine". https://www.cdc.gov/h1n1flu/vaccination/public/vaccination_qa_pub.htm. 
  9. "Use of Influenza A (H1N1) 2009 Monovalent Vaccine". https://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm. 
  10. Schnirring, Lisa; Apr 17, Robert Roos |; 2007. "FDA approves first H5N1 vaccine" (in en). https://www.cidrap.umn.edu/news-perspective/2007/04/fda-approves-first-h5n1-vaccine. 
  11. Dan Brennan, MD (2021-01-10). "What Are The Side Effects of the H1N1 Flu Vaccine?". MedicinNet. https://www.medicinenet.com/what_are_the_side_effects_of_the_h1n1_flu_vaccine/article.htm. 
  12. "Safety and Immunogenicity of an Inactivated - ProQuest" (in en). https://www.proquest.com/docview/223926971. 
  13. "Influenza H1N1 Vaccine - FDA prescribing information, side effects and uses" (in en). https://www.drugs.com/pro/influenza-h1n1-vaccine.html. 
  14. Tomi O Sarkanen , Anniina P E Alakuijala, Yves A Dauvilliers , Markku M Partinen (2017-06-20). "Incidence of narcolepsy after H1N1 influenza and vaccinations: Systematic review and meta-analysis". PubMed. https://pubmed-ncbi-nlm-nih-gov.eproxy.lib.hku.hk/23954580/. 
  15. Public Health England. Influenza: the green book, chapter 19 (issued August 2015). In: Immunisation against infectious disease. London: Public Health England, 2015.
  16. "Vaccine Types". 2021-04-29. https://www.hhs.gov/immunization/basics/types/index.html. 
  17. Roberto Tinoco; James E. Crowe (2017). "Chapter 36: Immune Globulins and Vaccines" Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e.. McGraw Hill. 
  18. Riedel S, Hobden JA, Miller S, Morse SA, Mietzner TA, Detrick B, Mitchell TG, Sakanari JA, Hotez P, Mejia R. (2019). "Orthomyxoviruses (Influenza Viruses)", Melnick, & Adelberg's Medical Microbiology, 28e.. McGraw Hill. 
  19. "Cell-Based Flu Vaccines". 2021-11-23. https://www.cdc.gov/flu/prevent/cell-based.htm. 
  20. Garcia-Garcia, L.; Valdespino-Gomez, J. L.; Lazcano-Ponce, E.; Jimenez-Corona, A.; Higuera-Iglesias, A.; Cruz-Hervert, P.; Cano-Arellano, B.; Garcia-Anaya, A. et al. (2009-10-06). "Partial protection of seasonal trivalent inactivated vaccine against novel pandemic influenza A/H1N1 2009: case-control study in Mexico City". BMJ 339 (oct06 2): b3928. doi:10.1136/bmj.b3928. ISSN 0959-8138. PMID 19808768. PMC 2758337. http://dx.doi.org/10.1136/bmj.b3928. 
  21. Khardori, N.M. (Jan 2012). "A Cell Culture–Derived Influenza Vaccine Provides Consistent Protection Against Infection and Reduces the Duration and Severity of Disease in Infected Individuals". Yearbook of Medicine 2012: 89–91. doi:10.1016/j.ymed.2012.08.010. ISSN 0084-3873. http://dx.doi.org/10.1016/j.ymed.2012.08.010. 
  22. Kida, H.; Webster, R. G.; Yanagawa, R. (June 1983). "Inhibition of virus-induced hemolysis with monoclonal antibodies to different antigenic areas on the hemagglutinin molecule of A/seal/Massachusetts/1/80 (H7N7) influenza virus". Archives of Virology 76 (2): 91–99. doi:10.1007/bf01311693. ISSN 0304-8608. PMID 6191738. http://dx.doi.org/10.1007/bf01311693. 
  23. Dunkle, Lisa M.; Izikson, Ruvim (2016-07-04). "Recombinant hemagglutinin influenza vaccine provides broader spectrum protection". Expert Review of Vaccines 15 (8): 957–966. doi:10.1080/14760584.2016.1203261. ISSN 1476-0584. PMID 27314982. http://dx.doi.org/10.1080/14760584.2016.1203261. 
  24. Elisha, Hall (17 August 2021). "Epidemiology and Prevention of Vaccine-Preventable Diseases". https://www.cdc.gov/vaccines/pubs/pinkbook/flu.html. 
  25. "Influenza Historic Timeline | Pandemic Influenza (Flu) | CDC" (in en-us). 2020-03-11. https://www.cdc.gov/flu/pandemic-resources/pandemic-timeline-1930-and-beyond.htm. 
  26. "How Long Did It Take to Develop the Flu Vaccine? | The Weather Channel - Articles from The Weather Channel | weather.com" (in en-US). https://weather.com/health/news/2021-01-21-how-long-did-it-take-to-develop-the-flu-shot. 
  27. "History of Flu (Influenza): Outbreaks and Vaccine Timeline" (in en). https://www.mayoclinic.org/coronavirus-covid-19/history-disease-outbreaks-vaccine-timeline/flu. 
  28. "Global Influenza Surveillance and Response System (GISRS)" (in en). https://www.who.int/initiatives/global-influenza-surveillance-and-response-system. 
  29. Research, Center for Biologics Evaluation and (2019-04-12). "H5N1 Influenza Virus Vaccine, manufactured by Sanofi Pasteur, Inc. Questions and Answers" (in en). FDA. https://www.fda.gov/vaccines-blood-biologics/vaccines/h5n1-influenza-virus-vaccine-manufactured-sanofi-pasteur-inc-questions-and-answers. 
  30. Clegg, Christopher H; Rininger, Joseph A; Baldwin, Susan L (July 2013). "Clinical vaccine development for H5N1 influenza". Expert Review of Vaccines 12 (7): 767–777. doi:10.1586/14760584.2013.811178. ISSN 1476-0584. PMID 23885822.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=6101019
  31. CDC (2019-05-08). "2009 H1N1 Flu Pandemic Timeline" (in en-us). https://www.cdc.gov/flu/pandemic-resources/2009-pandemic-timeline.html. 
  32. CDC (2021-11-02). "Types of Influenza Viruses" (in en-us). https://www.cdc.gov/flu/about/viruses/types.htm. 
  33. Bulletin of the World Health Organization. 1980. pp. 585–591. 
  34. John P. Cunha, DO, FACOEP (2021-03-11). "INFLUENZA A H1N1 MONOVALENT VACCINE". RxList. https://www.rxlist.com/influenza-a-h1n1-monovalent-vaccine-drug.htm. 
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