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Odegaard, K.; Pendyala, G.; Yelamanchili, S.V. Generational Effects of Opioid Exposure. Encyclopedia. Available online: https://encyclopedia.pub/entry/6354 (accessed on 03 October 2026).
Odegaard K, Pendyala G, Yelamanchili SV. Generational Effects of Opioid Exposure. Encyclopedia. Available at: https://encyclopedia.pub/entry/6354. Accessed October 03, 2026.
Odegaard, Katherine, Gurudutt Pendyala, Sowmya V. Yelamanchili. "Generational Effects of Opioid Exposure" Encyclopedia, https://encyclopedia.pub/entry/6354 (accessed October 03, 2026).
Odegaard, K., Pendyala, G., & Yelamanchili, S.V. (2021, January 13). Generational Effects of Opioid Exposure. In Encyclopedia. https://encyclopedia.pub/entry/6354
Odegaard, Katherine, et al. "Generational Effects of Opioid Exposure." Encyclopedia. Web. 13 January, 2021.
Peer Reviewed
Generational Effects of Opioid Exposure
This is a peer-reviewed entry published in Encyclopedia Journal, full entry can be found at https://doi.org/10.3390/encyclopedia1010012

The inheritance of substance abuse, including opioid abuse, may be influenced by genetic and non-genetic factors related to the environment, such as stress and socioeconomic status. These non-genetic influences on the heritability of a trait can be attributed to epigenetics. Epigenetic inheritance can result from modifications passed down from the mother, father, or both, resulting in either maternal, paternal, or parental epigenetic inheritance, respectively. These epigenetic modifications can be passed to the offspring to result in multigenerational, intergenerational, or transgenerational inheritance. Human and animal models of opioid exposure have shown generational effects that result in molecular, developmental, and behavioral alterations in future generations. 

Keywords: opioids morphine heroin oxycodone multigenerational intergenerational transgenerational humans animals

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Subjects: Tropical Medicine
Contributors MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Katherine Odegaard , Gurudutt Pendyala , Sowmya V. Yelamanchili
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Online Date: 13 Jan 2021
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