The factors that influence electrical potential across the cell membrane are important because they affect cellular properties that, in turn, allow tissues, organs, and whole organism to function; as such, it is important to understand them. The distribution and movement of certain ions (i.e., Na⁺, K⁺, Ca²⁺) determine this electrical potential as they move across the membrane through channels and transport processes, some of which are impeded by the presence of other ions. As a particularly apt example: free Ca²⁺ ions are known to block open Na⁺ channels. This study illustrated that raising the Ca²⁺ ion concentration on one side of the membrane led to a larger membrane potential, and this is suggested herein to be caused by blockage of a leaky Na⁺ channel. If more such channels are present in the membrane, the effects of altering Ca²⁺ concentration have less impact.