Tulip (scientific name: Tulipa gesneriana) is a cultivated species of the genus Tulip in the family Liliaceae, also known as foreign lotus and dry lotus. The origin is Tianshan Mountain in China.
Tulip (scientific name: Tulipa gesneriana) is a cultivated species of the genus Tulip in the family Liliaceae, also known as foreign lotus and dry lotus. The origin is Tianshan Mountain in China.
This negatively-stained 1975 transmission electron micrograph (TEM) revealed the presence of a number of human coronavirus, HCoV-229E virions. This organism is a member of the family, Coronaviridae, and the genus Coronavirus. The coronavirus helical genome is composed of positive-sense single-stranded RNA ((+) ssRNA). This is an enveloped virus, which means that its outermost covering is derived from the host cell membrane.
This negatively-stained 1975 transmission electron micrograph (TEM) revealed the presence of a number of human coronavirus, HCoV-229E virions. This organism is a member of the family, Coronaviridae, and the genus Coronavirus. The coronavirus helical genome is composed of positive-sense single-stranded RNA ((+) ssRNA). This is an enveloped virus, which means that its outermost covering is derived from the host cell membrane.
This negatively-stained transmission electron micrograph (TEM) revealed the presence of numerous herpes simplex virions, members of the Herpesviridae virus family. There are two strains of the herpes simplex virus, HSV-1, which is responsible for cold sores, and HSV-2, which is responsible for genital herpes. At the core of its icosahedral proteinaceous capsid, the HSV contains a double-stranded DNA linear genome.
This negatively-stained transmission electron micrograph (TEM) revealed the presence of numerous herpes simplex virions, members of the Herpesviridae virus family. There are two strains of the herpes simplex virus, HSV-1, which is responsible for cold sores, and HSV-2, which is responsible for genital herpes. At the core of its icosahedral proteinaceous capsid, the HSV contains a double-stranded DNA linear genome.
Electron micrograph (SEM) of acicular Sb2S3 crystals obtained by thermal decomposition of pure antimony dodecyl-thiolate (Sb(SC12H25)3). Polymeric nanocomposites can be obtained by thermal decomposition of the same metal thiolate dissolved in a polymeric matrix (e.g., amorphous polystyrene) [1]. This nanocomposite material has very useful optical properties (fluorescence).
Electron micrograph (SEM) of acicular Sb2S3 crystals obtained by thermal decomposition of pure antimony dodecyl-thiolate (Sb(SC12H25)3). Polymeric nanocomposites can be obtained by thermal decomposition of the same metal thiolate dissolved in a polymeric matrix (e.g., amorphous polystyrene) [1]. This nanocomposite material has very useful optical properties (fluorescence).
Inflammation is considered as a potential mechanism in intrauterine growth restriction (IUGR). It was postulated, based on findings from a few case-control studies in humans, that aberrant inflammation in gravidas and/or newborns could lead to IUGR. Serum levels of pro-inflammatory markers, including Interleukins (IL)-4/6/8/12, interferon (IFN)-γ, tumor necrosis factor (TNFα), high-sensitivity C-reactive protein (hsCRP), and erythrocyte sedimentation rate (ESR) were found to be higher in IUGR gravidas/infants than healthy counterparts [1].
Inflammation is considered as a potential mechanism in intrauterine growth restriction (IUGR). It was postulated, based on findings from a few case-control studies in humans, that aberrant inflammation in gravidas and/or newborns could lead to IUGR. Serum levels of pro-inflammatory markers, including Interleukins (IL)-4/6/8/12, interferon (IFN)-γ, tumor necrosis factor (TNFα), high-sensitivity C-reactive protein (hsCRP), and erythrocyte sedimentation rate (ESR) were found to be higher in IUGR gravidas/infants than healthy counterparts [1].
Overview diagram of vesicular stomatitis virus (VSV) life cycle. Steps of virus life cycle: attachment, endocytosis, uncoating, genome replication, mRNA transcription, viral protein translation, viral assembly, and budding are shown. [1]
Overview diagram of vesicular stomatitis virus (VSV) life cycle. Steps of virus life cycle: attachment, endocytosis, uncoating, genome replication, mRNA transcription, viral protein translation, viral assembly, and budding are shown. [1]
Holly R. Hughes, Scott Adkins, Sergey Alkhovskiy, Martin Beer, Carol Blair, Charles H. Calisher, Mike Drebot, Amy J. Lambert, William Marciel de Souza, Marco Marklewitz, Márcio R. T. Nunes, Xiǎohóng Shí (石晓宏), and ICTV Report Consortium; CDC
01 Apr 2024
Peribunyavirus virion structure. (a) Representation of a virion in cross-section. The surface spikes comprise the Gn and Gc glycoproteins. The helical nucleocapsids are circular and comprise one each of the unique ssRNA segments (L, large; M, medium; S, small) encapsidated by N protein and associated with the L protein. (b) Negative-stained transmission electron microscopy photograph of California encephalitis virus virions.
Peribunyavirus virion structure. (a) Representation of a virion in cross-section. The surface spikes comprise the Gn and Gc glycoproteins. The helical nucleocapsids are circular and comprise one each of the unique ssRNA segments (L, large; M, medium; S, small) encapsidated by N protein and associated with the L protein. (b) Negative-stained transmission electron microscopy photograph of California encephalitis virus virions.
Holly R. Hughes, Scott Adkins, Sergey Alkhovskiy, Martin Beer, Carol Blair, Charles H. Calisher, Mike Drebot, Amy J. Lambert, William Marciel de Souza, Marco Marklewitz, Márcio R. T. Nunes, Xiǎohóng Shí (石晓宏), and ICTV Report Consortium; CDC
The human heart is a muscular organ roughly the size of a fist, located slightly to the left of the midline in the thoracic cavity. It is central to the circulatory system, responsible for pumping blood throughout the body. The heart is enclosed in a double-walled sac called the pericardium, which protects and anchors it within the chest.[1]
The human heart is a muscular organ roughly the size of a fist, located slightly to the left of the midline in the thoracic cavity. It is central to the circulatory system, responsible for pumping blood throughout the body. The heart is enclosed in a double-walled sac called the pericardium, which protects and anchors it within the chest.[1]
Colorized scanning electron micrograph of Ebola virus particles (yellow) both budding and attached to the surface of infected VERO E6 cells (green). Image captured and color-enhanced at the NIAID Integrated Research Facility in Fort Detrick, Maryland.
Colorized scanning electron micrograph of Ebola virus particles (yellow) both budding and attached to the surface of infected VERO E6 cells (green). Image captured and color-enhanced at the NIAID Integrated Research Facility in Fort Detrick, Maryland.
Rutin (RU), also known as Q-3-O-rutinoside, is a flavonol compound found in various fruits and vegetables. RU could be useful in the treatment of non-small cell lung cancer (NSCLC) mediated by nicotinic acetylcholine receptor α7nAChR. A few in vivo/vitro studies showed that RU exerts anti-proliferative, anti-migration, anti-adhesion, apoptotic, and autophagic effects on nicotine-induced NSCLC cells [1].
Rutin (RU), also known as Q-3-O-rutinoside, is a flavonol compound found in various fruits and vegetables. RU could be useful in the treatment of non-small cell lung cancer (NSCLC) mediated by nicotinic acetylcholine receptor α7nAChR. A few in vivo/vitro studies showed that RU exerts anti-proliferative, anti-migration, anti-adhesion, apoptotic, and autophagic effects on nicotine-induced NSCLC cells [1].
Wikimedia Commons, Javier Orlando Cifuente and Gonzalo Moratorio
25 Jan 2024
(A, B) Picornavirus uses different receptors to enter the cell, some implicated in the signaling internalization (A), meanwhile others can act as carriers that transport the viral particle to meet the primary receptor (B). (C, D) This infection event can be impeded by the action of specific neutralizing antibodies that can destabilize the viral particle (C) or opsonize or stabilize the particle to impair receptor binding or conformational changes required for infection (D). (E) Once the virus enters the cell, the viral RNA delivery mechanism is triggered, and the viral genome (black wavy line) is released into the cytoplasm. (F) Upon removal of VPg (magenta oval), the genome starts the IRES-driven translation leading to the production of the viral polyprotein. (G) The proteolytic cascade produces all viral proteins, structural and non-structural. (H) Some proteins act by hijacking the host cellular systems such as the nuclear pore, the cell translation machinery, and the apoptotic systems and initiate the remodeling of the internal cell membranes. (I) The structural proteins assemble into the capsid intermediates, the protomer and the pentamer, and also procapsids (L). (J) The formed replication complex assembled from non-structural proteins and modified internal membranes firing the picornaviral genome replication by the 3D polymerase via RNA complementary (red wavy lines) and using VPg as a primer. (K) The new progeny genomes including eventual mutations (yellow stars). (M) Mature virions assemble from pentamers that surround and package the new viral genomes. Viral particles escape from the cell by cell lysis or budding within membranes that can protect the viral progeny (P). (N) Some progeny virus with mutations in their capsids (yellow star) may escape from to the action of specific NAbs. (O) Empty capsids can act as molecular decoys for Abs to protect the infecting particles from neutralization. [1]
(A, B) Picornavirus uses different receptors to enter the cell, some implicated in the signaling internalization (A), meanwhile others can act as carriers that transport the viral particle to meet the primary receptor (B). (C, D) This infection event can be impeded by the action of specific neutralizing antibodies that can destabilize the viral particle (C) or opsonize or stabilize the particle to impair receptor binding or conformational changes required for infection (D). (E) Once the virus enters the cell, the viral RNA delivery mechanism is triggered, and the viral genome (black wavy line) is released into the cytoplasm. (F) Upon removal of VPg (magenta oval), the genome starts the IRES-driven translation leading to the production of the viral polyprotein. (G) The proteolytic cascade produces all viral proteins, structural and non-structural. (H) Some proteins act by hijacking the host cellular systems such as the nuclear pore, the cell translation machinery, and the apoptotic systems and initiate the remodeling of the internal cell membranes. (I) The structural proteins assemble into the capsid intermediates, the protomer and the pentamer, and also procapsids (L). (J) The formed replication complex assembled from non-structural proteins and modified internal membranes firing the picornaviral genome replication by the 3D polymerase via RNA complementary (red wavy lines) and using VPg as a primer. (K) The new progeny genomes including eventual mutations (yellow stars). (M) Mature virions assemble from pentamers that surround and package the new viral genomes. Viral particles escape from the cell by cell lysis or budding within membranes that can protect the viral progeny (P). (N) Some progeny virus with mutations in their capsids (yellow star) may escape from to the action of specific NAbs. (O) Empty capsids can act as molecular decoys for Abs to protect the infecting particles from neutralization. [1]
Wikimedia Commons, Javier Orlando Cifuente and Gonzalo Moratorio
This infographic highlights key facts about SpaceX's ambitious project to provide global high-speed internet through a constellation of low Earth orbit satellites. Explore how Starlink is revolutionizing connectivity worldwide.
This infographic highlights key facts about SpaceX's ambitious project to provide global high-speed internet through a constellation of low Earth orbit satellites. Explore how Starlink is revolutionizing connectivity worldwide.
Cluster flies are a type of fly belonging to the genus Pollenia. They are often associated with rural or agricultural areas and can be found in many parts of the world. These flies are known for their habit of clustering together in large numbers, particularly during the autumn months when they seek shelter to hibernate during the winter.
Cluster flies are a type of fly belonging to the genus Pollenia. They are often associated with rural or agricultural areas and can be found in many parts of the world. These flies are known for their habit of clustering together in large numbers, particularly during the autumn months when they seek shelter to hibernate during the winter.
Wikimedia Commons, Alexander McPherson & Lawrence James DeLucas
14 Mar 2024
An array of crystals grown in the dewar device that used liquid–liquid diffusion from frozen biphasic samples. This experiment was performed by American investigators (Koszelak et al.75) on the Russian Space Station Mir. The crystals (labeled by row from left to right) are of top row: (a) rhombohedral canavalin, (b) creatine kinase, (c) lysozyme, (d) beef catalase; middle row: (e) porcine alpha amylase, (f) fungal catalase, (g) myglobin, (h) concanavalin B; and bottom row: (i) thaumatin, (j) apoferritin, (k) satellite tobacco mosaic virus (STMV), (l) hexagonal canavalin. [1]
An array of crystals grown in the dewar device that used liquid–liquid diffusion from frozen biphasic samples. This experiment was performed by American investigators (Koszelak et al.75) on the Russian Space Station Mir. The crystals (labeled by row from left to right) are of top row: (a) rhombohedral canavalin, (b) creatine kinase, (c) lysozyme, (d) beef catalase; middle row: (e) porcine alpha amylase, (f) fungal catalase, (g) myglobin, (h) concanavalin B; and bottom row: (i) thaumatin, (j) apoferritin, (k) satellite tobacco mosaic virus (STMV), (l) hexagonal canavalin. [1]
Wikimedia Commons, Alexander McPherson & Lawrence James DeLucas
Stroke is a neurological disorder characterized by blockage of blood vessels. Clots form in the brain and interrupt blood flow, clogging arteries and causing blood vessels to break, leading to bleeding. Rupture of the arteries leading to the brain during stroke results in the sudden death of brain cells owing to a lack of oxygen. Stroke can also lead to depression and dementia.
Stroke is a neurological disorder characterized by blockage of blood vessels. Clots form in the brain and interrupt blood flow, clogging arteries and causing blood vessels to break, leading to bleeding. Rupture of the arteries leading to the brain during stroke results in the sudden death of brain cells owing to a lack of oxygen. Stroke can also lead to depression and dementia.