Summary

HandWiki is the world's largest wiki-style encyclopedia dedicated to science, technology and computing. It allows you to create and edit articles as long as you have external citations and login account. In addition, this is a content management environment that can be used for collaborative editing of original scholarly content, such as books, manuals, monographs and tutorials.

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Atypical Depression
Atypical depression as it has been known in the DSM IV, is depression that shares many of the typical symptoms of the psychiatric syndromes of major depression or dysthymia but is characterized by improved mood in response to positive events. In contrast to atypical depression, people with melancholic depression generally do not experience an improved mood in response to normally pleasurable events. Atypical depression also features significant weight gain or an increased appetite, hypersomnia, a heavy sensation in the limbs, and interpersonal rejection sensitivity that results in significant social or occupational impairment. Despite its name, "atypical" depression does not mean it is uncommon or unusual. The reason for its name is twofold: it was identified with its "unique" symptoms subsequent to the identification of melancholic depression and its responses to the two different classes of antidepressants that were available at the time were different from melancholic depression (i.e., MAOIs had clinically significant benefits for atypical depression, while tricyclics did not). Atypical depression is four times more common in females than in males. Individuals with atypical features tend to report an earlier age of onset (e.g. while in high school) of their depressive episodes, which also tend to be more chronic and only have partial remission between episodes. Younger individuals may be more likely to have atypical features, whereas older individuals may more often have episodes with melancholic features. Atypical depression has high comorbidity of anxiety disorders, carries more risk of suicidal behavior, and has distinct personality psychopathology and biological traits. Atypical depression is more common in individuals with bipolar I, bipolar II, cyclothymia and seasonal affective disorder. Depressive episodes in bipolar disorder tend to have atypical features, as does depression with seasonal patterns.
  • 1.5K
  • 02 Nov 2022
Topic Review
Spotted Skunk
The genus Spilogale includes all skunks commonly known as spotted skunks and is composed of four extant species: S. gracilis, S. putorius, S. pygmaea, and S. angustifrons.
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  • 02 Nov 2022
Topic Review
Panzer II Variants
The Panzerkampfwagen II (Pz.Kpfw.II) light tank, produced in Germany in the late 1930s and early 1940s had a wide array of variants, both as development of the light tank and for specialised tasks.
  • 5.8K
  • 02 Nov 2022
Topic Review
Intel 80486
The Intel 80486, also known as the i486 or 486, is a higher performance follow-up to the Intel 80386 microprocessor. The 80486 was introduced in 1989 and was the first tightly pipelined x86 design as well as the first x86 chip to use more than a million transistors, due to a large on-chip cache and an integrated floating-point unit. It represents a fourth generation of binary compatible CPUs since the original 8086 of 1978. A 50 MHz 80486 executes around 40 million instructions per second on average and is able to reach 50 MIPS peak performance. Approximately twice as fast as the 80386 or 80286 per clock cycle, thanks to its five stage pipeline with all stages bound to a single cycle. The on chip enhanced FPU unit was also significantly faster than the 80387 per cycle.
  • 10.4K
  • 03 Nov 2022
Topic Review
Transmission (Mechanics)
A transmission is a machine in a power transmission system, which provides controlled application of power. Often the term 5-speed transmission refers simply to the gearbox, that uses gears and gear trains to provide speed and torque block conversions from a rotating power source to another device. The term transmission properly refers to the whole drivetrain, including clutch, gearbox, prop shaft (for rear-wheel drive vehicles), differential, and final drive shafts. In the United States the term is sometimes used in casual speech to refer more specifically to the gearbox alone, and detailed usage differs. The most common use is in motor vehicles, where the transmission adapts the output of the internal combustion engine to the drive wheels. Such engines need to operate at a relatively high rotational speed, which is inappropriate for starting, stopping, and slower travel. The transmission reduces the higher engine speed to the slower wheel speed, increasing torque in the process. Transmissions are also used on pedal bicycles, fixed machines, and where different rotational speeds and torques are adapted. Often, a transmission has multiple gear ratios (or simply "gears") with the ability to switch between them as the speed varies. This switching may be done manually (by the operator) or automatically (by a control unit). Directional (forward and reverse) control may also be provided. Single-ratio transmissions also exist, which simply change the speed and torque (and sometimes direction) of motor output. In motor vehicles, the transmission generally is connected to the engine crankshaft via a flywheel or clutch or fluid coupling, partly because internal combustion engines cannot run below a particular speed. The output of the transmission is transmitted via the driveshaft to one or more differentials, which drive the wheels. While a differential may also provide gear reduction, its primary purpose is to permit the wheels at either end of an axle to rotate at different speeds (essential to avoid wheel slippage on turns) as it changes the direction of rotation. Conventional gear/belt transmissions are not the only mechanism for speed/torque adaptation. Alternative mechanisms include torque converters and power transformation (e.g. diesel-electric transmission and hydraulic drive system). Hybrid configurations also exist. Automatic transmissions use a valve body to shift gears using fluid pressures in response to engine RPM, speed, and throttle input.
  • 5.7K
  • 01 Nov 2022
Topic Review
Grand Power K100
The K100 is a 9×19mm semi-automatic pistol designed and built by Grand Power s.r.o. in Slovenská Ľupča, Slovakia located approximately 11 kilometers east of Banská Bystrica, Slovakia which is the region's major city.
  • 2.8K
  • 03 Nov 2022
Topic Review
Reference Point Indentation
Reference Point Indentation (RPI) refers to a specialized form of indentation testing. RPI utilizes a unique method of measurement by establishing a relative reference point at the location of measurement. This unique capability makes it possible to measure materials that are in motion, oddly shaped, visco-elastic, or that may be coated or covered by another, softer material. Unlike traditional indentation testing, RPI testing uses the location of measurement as the relative displacement reference position. Indentation itself is perhaps the most commonly applied means of testing the mechanical properties of materials. The technique has its origins in the Mohs scale of mineral hardness, in which materials are ranked according to what they can scratch and are, in turn, scratched by. The characterization of solids in this way takes place on an essentially discrete scale, so much effort has been expended in order to develop techniques for evaluating material hardness over a continuous range. Hence, the adoption of the Meyer, Knoop, Brinell, Rockwell, and Vickers hardness tests. More recently (ca. 1975), nanoindentation techniques have been established as the primary tool for investigating the hardness of small volumes of material. However, even more recently (ca. 2006), interest in measuring functional roles of biomaterials drove the development of the Reference Point Indentation technique. New research in field such as biomaterials has led scientists to begin considering materials as complex systems that behave differently than the constituent parts. For example, materials like bone are hierarchical and made of many components including calcium, collagen, water, and non-collagenous proteins. Each of these components has unique material properties. When combined to form bone, the function of the tissue is different than any one constituent. Understanding this mechanical system is becoming a new field of research called Materiomics. RPI specifically aims to aid materiomics researchers understand the functional capabilities of these types of materials at a relevant length-scale.
  • 958
  • 01 Nov 2022
Topic Review
List of Medical Wikis
This is a list of medical wikis, collaboratively-editable websites that focus on medical information. Many of the most popular medical wikis take the form of encyclopedias, with a separate article for each medical term. Some of these websites, such as WikiDoc and Radiopaedia, are editable by anyone, while others, such as Ganfyd, restrict editing access to professionals. The majority of them have content available only in English. The largest and most popular general encyclopedia, Wikipedia, also hosts a significant amount of health and medical information.
  • 2.2K
  • 01 Nov 2022
Topic Review
Gaming Computer
A gaming computer, also known as a gaming PC, is a specialized personal computer designed for playing video games. Gaming PCs typically differ from mainstream personal computers by using high-performance video cards and high core-count central processing units with raw performance. Gaming PCs are also used for other demanding tasks such as video editing. Many gamers and computer enthusiasts choose to overclock their CPU(s) and GPU(s) in order to gain extra performance. The added power draw needed to overclock either processing unit often requires additional cooling, using upgraded air cooling or water cooling.
  • 11.3K
  • 01 Nov 2022
Topic Review
Vienna Philharmonic (Coin)
The Vienna Philharmonic (German: Wiener Philharmoniker), often shortened to Philharmonic, is a bullion coin of gold, silver, or platinum produced by the Austrian Mint (Münze Österreich). The coin is named for the Vienna Philharmonic orchestra, which inspired the design of both sides. It was introduced in 1989 as a one-troy ounce (ozt), gold coin with a face value of 2,000 Austrian schillings. It is generally one of the world's best selling bullion coins. In 2002, with the adoption of the euro currency, the nominal value of the one-ounce coin was changed to 100 euros. In 2008, the Mint introduced a one-ounce silver version of the coin with a nominal value of 1.50 euros. The silver coin is also one of the top selling bullion coins, ranked third in 2013. In 2016, the mint introduced a one ounce platinum coin with a face value of 100 euros. Like any bullion coin, the value is based primarily on the metal content and the spot price of that metal on the commodities markets. The gold Philharmonic has a fineness of 999.9 (often written 0.9999, also known as 24 carat or 99.99% pure). In most countries in Europe, the gold Philharmonic is traded VAT-free while the Silver Philharmonic is partly subject to a reduced VAT rate. The coins are minted according to demand and production varies from year to year accordingly. The design on the coin remains the same each year; only the year of issue changes. From the outset, the obverse of the coin depicts the pipe organ in the Vienna Musikverein's Golden Hall. The reverse of the coin shows instruments of the Vienna Philharmonic, including Vienna horn, bassoon, harp, and four violins centered on a cello. Both designs were produced by the chief engraver of the Austrian Mint, Thomas Pesendorfer.
  • 1.3K
  • 01 Nov 2022
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