Summary

HandWiki is the world's largest wiki-style encyclopedia dedicated to science, technology and computing. It allows you to create and edit articles as long as you have external citations and login account. In addition, this is a content management environment that can be used for collaborative editing of original scholarly content, such as books, manuals, monographs and tutorials.

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Intrusive Thought
An intrusive thought is an unwelcome, involuntary thought, image, or unpleasant idea that may become an obsession, is upsetting or distressing, and can feel difficult to manage or eliminate. When such thoughts are associated with obsessive-compulsive disorder (OCD), depression, body dysmorphic disorder (BDD), and sometimes attention-deficit hyperactivity disorder (ADHD), the thoughts may become paralyzing, anxiety-provoking, or persistent. Intrusive thoughts may also be associated with episodic memory, unwanted worries or memories from OCD, post-traumatic stress disorder, other anxiety disorders, eating disorders, or psychosis. Intrusive thoughts, urges, and images are of inappropriate things at inappropriate times, and generally have aggressive, sexual, or blasphemous themes.
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  • 10 Nov 2022
Topic Review
ICANN
The Internet Corporation for Assigned Names and Numbers (ICANN /ˈaɪkæn/ EYE-kan) is an American multistakeholder group and nonprofit organization responsible for coordinating the maintenance and procedures of several databases related to the namespaces and numerical spaces of the Internet, ensuring the network's stable and secure operation. ICANN performs the actual technical maintenance work of the Central Internet Address pools and DNS root zone registries pursuant to the Internet Assigned Numbers Authority (IANA) function contract. The contract regarding the IANA stewardship functions between ICANN and the National Telecommunications and Information Administration (NTIA) of the United States Department of Commerce ended on October 1, 2016, formally transitioning the functions to the global multistakeholder community. Much of its work has concerned the Internet's global Domain Name System (DNS), including policy development for internationalization of the DNS system, introduction of new generic top-level domains (TLDs), and the operation of root name servers. The numbering facilities ICANN manages include the Internet Protocol address spaces for IPv4 and IPv6, and assignment of address blocks to regional Internet registries. ICANN also maintains registries of Internet Protocol identifiers. ICANN's primary principles of operation have been described as helping preserve the operational stability of the Internet; to promote competition; to achieve broad representation of the global Internet community; and to develop policies appropriate to its mission through bottom-up, consensus-based processes. ICANN's creation was announced publicly on September 17, 1998, and it formally came into being on September 30, 1998, incorporated in the U.S. state of California. Originally headquartered in Marina del Rey in the same building as the University of Southern California's Information Sciences Institute (ISI), its offices are now in the Playa Vista neighborhood of Los Angeles in Facebook's old office.
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  • 10 Nov 2022
Topic Review
Bible Study (Christian)
In Christian communities, Bible study is the study of the Bible by ordinary people as a personal religious or spiritual practice. Some denominations may call this devotion or devotional acts; however in other denominations devotion has other meanings. Bible study in this sense is distinct from biblical studies, which is a formal academic discipline.
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  • 10 Nov 2022
Topic Review
Great Disappointment
The Great Disappointment in the Millerite movement was the reaction that followed Baptist preacher William Miller's proclamations that Jesus Christ would return to the Earth by 1844, what he called the Advent. His study of the Daniel 8 prophecy during the Second Great Awakening led him to the conclusion that Daniel's "cleansing of the sanctuary" was cleansing of the world from sin when Christ would come, and he and many others prepared, but October 22, 1844 came, and they were disappointed. These events paved the way for the Adventists who formed the Seventh-day Adventist Church. They contended that what had happened on October 22 was not Jesus' return, as Miller had thought, but the start of Jesus' final work of atonement, the cleansing in the heavenly sanctuary, leading up to the Second Coming.
  • 3.2K
  • 10 Nov 2022
Topic Review
Neoliberalism (International Relations)
In the study of international relations, neoliberalism (or liberal institutionalism) is a school of thought which holds that international cooperation between states is feasible and sustainable, and that such cooperation can reduce conflict and competition. Neoliberalism is a revised version of liberalism. Alongside neorealism, neoliberalism is one of the two most influential contemporary approaches to international relations; the two perspectives have dominated international relations theory since the 1990s. Neoliberalism shares many assumptions as neorealism (namely, that the international system is anarchic, states are the main actors, and states rationally pursue their self-interest), but draws different conclusions from those assumptions. In contrast to neorealist scholarship which is skeptical of prospects for sustainable cooperation, neoliberalism argues that cooperation is feasible and sustainable. Neoliberals highlight the role of international institutions and regimes in facilitating cooperation between states. The main reason why international organizations facilitate cooperation is that they provide information, which reduces collective action problems among states in providing public goods and enforcing compliance. Robert Keohane's 1984 book After Hegemony used insights from the new institutional economics to argue that the international system could remain stable in the absence of a hegemon, thus rebutting hegemonic stability theory. Keohane showed that international cooperation could be sustained through repeated interactions, transparency, and monitoring.
  • 58.2K
  • 10 Nov 2022
Topic Review
Alpha 1-Antitrypsin Deficiency
Alpha-1 antitrypsin deficiency (A1AD or AATD) is a genetic disorder that may result in lung disease or liver disease. Onset of lung problems is typically between 20 and 50 years old. This may result in shortness of breath, wheezing, or an increased risk of lung infections. Complications may include COPD, cirrhosis, neonatal jaundice, or panniculitis. A1AD is due to a mutation in the SERPINA1 gene that results in not enough alpha-1 antitrypsin (A1AT). Risk factors for lung disease include cigarette smoking and environmental dust. The underlying mechanism involves unblocked neutrophil elastase and build up of abnormal A1AT in the liver. It is autosomal co-dominant, meaning that one defective allele tends to result in milder disease than two defective alleles. The diagnosis is suspected based on symptoms and confirmed by blood tests or genetic tests. Treatment of lung disease may include bronchodilators, inhaled steroids, and when infections occur antibiotics. Intravenous infusions of the A1AT protein or in severe disease lung transplantation may also be recommended. In those with severe liver disease liver transplantation may be an option. Avoiding smoking is recommended. Vaccination for influenza, pneumococcus, and hepatitis is also recommended. Life expectancy among those who smoke is 50 years old while among those who do not smoke it is almost normal. The condition affects about 1 in 2,500 people of Europeans descent. Severe deficiency occurs in about 1 in 5,000. In Asians it is uncommon. About 3% of people with COPD are believed to have the condition. Alpha-1 antitrypsin deficiency was first described in the 1960s.
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  • 11 Nov 2022
Topic Review
Japan Median Tectonic Line
Japan Median Tectonic Line (中央構造線, Chūō Kōzō Sen), also Median Tectonic Line (MTL), is Japan's longest fault system. The MTL begins near Ibaraki Prefecture, where it connects with the Itoigawa-Shizuoka Tectonic Line (ISTL) and the Fossa Magna. It runs parallel to Japan's volcanic arc, passing through central Honshū to near Nagoya, through Mikawa Bay, then through the Inland Sea from the Kii Channel and Naruto Strait to Shikoku along the Sadamisaki Peninsula and the Bungo Channel and Hōyo Strait to Kyūshū. The sense of motion on the MTL is right-lateral strike-slip, at a rate of about 5–10 mm/yr. This sense of motion is consistent with the direction of oblique convergence at the Nankai Trough. The rate of motion on the MTL is much less than the rate of convergence at the plate boundary, making it difficult to distinguish the motion on the MTL from interseismic elastic straining in GPS data.
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  • 10 Nov 2022
Topic Review
Subvocalization
Subvocalization, or silent speech, is the internal speech typically made when reading; it provides the sound of the word as it is read. This is a natural process when reading, and it helps the mind to access meanings to comprehend and remember what is read, potentially reducing cognitive load. This inner speech is characterized by minuscule movements in the larynx and other muscles involved in the articulation of speech. Most of these movements are undetectable (without the aid of machines) by the person who is reading. It is one of the components of Baddeley and Hitch's phonological loop proposal which accounts for the storage of these types of information into short-term memory.
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  • 10 Nov 2022
Topic Review
Nimbarka Sampradaya
The Nimbarka Sampradaya (IAST: Nimbārka Sampradāya, Sanskrit निम्बार्क सम्प्रदाय), also known as the Hamsa Sampradāya, Kumāra Sampradāya, Catuḥ Sana Sampradāya and Sanakādi Sampradāya, is one of the four Vaiṣṇava Sampradāyas. It was founded by Nimbarka (c.7th century CE), and teaches the Vaishnava theology of Dvaitadvaita (dvaita-advaita) or "dualistic non-dualism." Dvaitadvaita states that humans are both different and non-different from Isvara, God or Supreme Being, and is also known as Bhedābheda (bheda-abheda) philosophy.
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  • 10 Nov 2022
Topic Review
Bioterrorism
Bioterrorism is the deliberate release of viruses, bacteria, toxins or other harmful agents to cause illness or death in people, animals, or plants.
  • 2.0K
  • 10 Nov 2022
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