Health-Promoting Beverages: Comparison
Please note this is a comparison between Version 3 by Dean Liu and Version 2 by shereen mohamed.

Tea, a beverage made from the processed leaves of the tea plant,

Camellia sinensis

, and herbal infusions, were primarily consumed to their pleasant taste. Nowadays, are also consumed due to the existence of nutraceutical compounds in the herbs used, such as polyphenols.

  • infusions
  • tea
  • tisanes
  • nutraceutical properties
  • human health

1.Introduction

1.1. Plant Infusions

Plant infusions, commonly called teas or tisanes, are the most popular form of herbal medicine in the world, being used for thousands of years. In fact, the habit of consuming teas and herbal infusions is increasingly embedded in the routine of Americans and Europeans [1] due to their potential health benefits, attractive flavor, and taste, or for its relatively low retail price [2].

However, most people do not know to distinguish tea from infusions and tisanes. An infusion consists of putting boiling water over a certain amount of parts of the plant in question (roots, flowers, leaves, seeds or twigs, or other), leave it to rest for a few minutes and strain [3]. The liquid resulting from this immersion is also called infusion. When an infusion is prepared from two or more different plants this can be named "tisane" [4]. The term "tea" should be used exclusively to designate infusions obtained from the leaves of the

Camellia sinensis

, a member of the Theaceae family plant, however, this denomination it is commonly used to describe an infusion prepared from any plant. infusions obtained from the leaves of

Camellia sinensis

, a member of the Theaceae family; however, this denomination is commonly used to describe an infusion prepared from any plant.

1.2. Tea and Other Herbal Infusions

White, green, oolong and black tea are different types of tea made from the leaves of the same species,

Camellia sinensis

, being the difference among them the post-harvest treatment which modifies the color of its leaves, its aroma, flavor, and number of polyphenols present (Figure 1).

Figure 1. The

Camellia sinensis

plant, and the different types of tea it produces. Photo adapted from Forest & Kim Starr-Jardim Botânico UTAD, 2019 [5].

 White tea, made from new growth buds and young leaves, is the least processed of all teas and, as a result, it has the most delicate flavor and aroma. The leaves are not rolled or crushed during processing but are plucked and dried in the sun and shade. This type of tea can be semifermented or non-fermented and releases the least amount of caffeine among all teas [7]. Sweet or flowery flavors are characteristic of this type of tea. The name “white tea” is due to the fact that it is made from unfolded tea buds with white trichomes which give a silvery appearance. It is one of the most expensive teas for the consumer [6]. White tea is consumed essentially by people concerned about their health since, because of its characteristics, it is considered to have a high therapeutic value [8].

 White tea, made from new growth buds and young leaves, is the least processed of all teas and, as a result, it has the most delicate flavor and aroma. The leaves are not rolled or crushed during processing but are plucked and dried in the sun and shade. This type of tea can be semifermented or non-fermented and releases the least amount of caffeine among all teas[7]. Sweet or flowery flavors are characteristic of this type of tea. The name “white tea” is due to the fact that it is made from unfolded tea buds with white trichomes which give a silvery appearance. It is one of the most expensive teas for the consumer [6]. White tea is consumed essentially by people concerned about their health since, because of its characteristics, it is considered to have a high therapeutic value [8].

Green tea is a less fermented tea and contains the highest quantity of tea catechins. To produce this type of tea, the leaves are steamed or pan-roasted to inactivate their enzymes and then are dried; drying preserves their constituents [7]. The main chemical constituents of dried green-tea leaves are polyphenols (37%), carbohydrates (25%), caffeine (15%), and amino acids (6.5%) [9]. Green tea has a fresh, grassy flavor, being more astringent and subtler than oolong or black tea [10].

Green tea is a less fermented tea and contains the highest quantity of tea catechins. To produce this type of tea, the leaves are steamed or pan-roasted to inactivate their enzymes and then are dried; drying preserves their constituents[7]. The main chemical constituents of dried green-tea leaves are polyphenols (37%), carbohydrates (25%), caffeine (15%), and amino acids (6.5%)[9]. Green tea has a fresh, grassy flavor, being more astringent and subtler than oolong or black tea[10].

Oolong tea is semi-fermented and also known as a hybrid of black and

green tea

. With characteristics of both black and green tea, sweet, fruity, and flower-like odors, this type of tea is the most preferred in China. Originally produced with

C. sinensis

var.

sinensis

in Fujian Province in southeast China, it is nowadays also cultured in other regions of China together with other subspecies such as

C. sinensis

var.

assamica [11].

[11].

Black tea is a totally fermented tea. Fermentation is an extremely important process for the development of tea aroma and flavor, which change progressively as the process develops. In fact, the scent of black tea depends on the formation of volatile substances consisting of essential oils and other molecules like amino acids [12]. Biochemically, the so-called “fermentation” process is, in fact, an oxidation which involves enzymatic reactions: after rupture, the tea leaves expose the cell sap (juice that is simply the cytoplasmatic content), whose chemical constituents and enzymes react in the presence of atmospheric oxygen [13,14]. The enzymes polyphenol oxidase and peroxidase act on catechins in the presence of oxygen and form oxidized polyphenolic compounds such as theaflavins and thearubigins [15]. The leaves’ cells are ruptured by rolling the leaves. According to Carloni and coworkers [16], this can be done by two distinct methodologies: using the “crush–tear–curl” process, which allows obtaining small particles suitable for tea bags, or using rolls, which provide large-leaf tea. Black teas are distinct for their honey and flower-like flavor [10].

Black tea is a totally fermented tea. Fermentation is an extremely important process for the development of tea aroma and flavor, which change progressively as the process develops. In fact, the scent of black tea depends on the formation of volatile substances consisting of essential oils and other molecules like amino acids[12]. Biochemically, the so-called “fermentation” process is, in fact, an oxidation which involves enzymatic reactions: after rupture, the tea leaves expose the cell sap (juice that is simply the cytoplasmatic content), whose chemical constituents and enzymes react in the presence of atmospheric oxygen[13][14]. The enzymes polyphenol oxidase and peroxidase act on catechins in the presence of oxygen and form oxidized polyphenolic compounds such as theaflavins and thearubigins[15]. The leaves’ cells are ruptured by rolling the leaves. According to Carloni and coworkers[16], this can be done by two distinct methodologies: using the “crush–tear–curl” process, which allows obtaining small particles suitable for tea bags, or using rolls, which provide large-leaf tea. Black teas are distinct for their honey and flower-like flavor[10].

Infusions can be prepared from a great diversity of edible, aromatic, and medicinal plants, besides

C. sinensis. The beverages obtained, since antiquity, are very pleasant due to their attractive flavor, taste, and biological and physiological functions, which are beneficial for human health [17,18]. Currently, the demand and use of plants to obtain infusions with medicinal purposes are increasing, and a great variety of these herbal products are available on the market. Many are obtained from plants that are familiar to the consumers. Table 1 shows some examples of aromatic and medicinal plants commonly used for the preparation of infusions, as well as their main benefits.

. The beverages obtained, since antiquity, are very pleasant due to their attractive flavor, taste, and biological and physiological functions, which are beneficial for human health[17][18]. Currently, the demand and use of plants to obtain infusions with medicinal purposes are increasing, and a great variety of these herbal products are available on the market. Many are obtained from plants that are familiar to the consumers. Table 1 shows some examples of aromatic and medicinal plants commonly used for the preparation of infusions, as well as their main benefits.

 Table 1 - Botanical names, families, medicinally used parts and health benefits of several aromatic and medicinal plants. Adapted from Herrera et al. [18].

1.3         Infusions and Health

1.3. Infusions and Health

There are several reasons why more and more consumers are drinking tea and infusions. Initially, the consumption of both tea and infusions was due to its taste and aroma and even to be rooted in the country's culture [20]. Nowadays, its consumption goes far beyond that, observing by the consumers an awareness that the chemical components contained in the tea leaves are of great interest, particularly with regard to health [21,22]. Several studies have already shown the close relationship between the consumption of foods rich in antioxidants and the incidence of certain diseases [23].

There are several reasons why more and more consumers are drinking tea and infusions. Initially, the consumption of both tea and infusions was due to its taste and aroma and even to be rooted in the country's culture [20]. Nowadays, its consumption goes far beyond that, observing by the consumers an awareness that the chemical components contained in the tea leaves are of great interest, particularly with regard to health[21][22]. Several studies have already shown the close relationship between the consumption of foods rich in antioxidants and the incidence of certain diseases[23]. Catechins (Figure 2) are the major components of green tea leaves[24].

Catechins (Figure 2) are the major components of green tea leaves [24].

Figure 2. Chemical structures of catechins present in of green tea.

In black tea, catechins are oxidized and dimerized during fermentation to the yellow-orange “pigments,” theaflavins, or polymerized to the red “pigments” called thearubigins. oolong tea contains a mixture of catechins, theaflavins, and thearubigins [24]. So, we can say that polyphenols, mainly the flavonoid: theaflavins, theaflavic acids, and bisflavanols, are considered the main chemical black tea compounds with powerful antioxidant properties (Figure 3) [25].

In black tea, catechins are oxidized and dimerized during fermentation to the yellow-orange “pigments,” theaflavins, or polymerized to the red “pigments” called thearubigins. oolong tea contains a mixture of catechins, theaflavins, and thearubigins[24]. So, we can say that polyphenols, mainly the flavonoid: theaflavins, theaflavic acids, and bisflavanols, are considered the main chemical black tea compounds with powerful antioxidant properties (Figure 3) [25].

Figure 3. Chemical structures of theaflavins, thearubigins, and bisflavanols in black tea.

The antioxidant activity of phenolic compounds is mainly due to their redox properties, which allow them to act as the free radical scavengers which remove endogenously generated superoxide, peroxyl and hydroxyl radicals [7]. In addition, they have a metal chelating potential [26].

The antioxidant activity of phenolic compounds is mainly due to their redox properties, which allow them to act as the free radical scavengers which remove endogenously generated superoxide, peroxyl and hydroxyl radicals[7]. In addition, they have a metal chelating potential[26]

Leung and co-workers [24] demonstrated that the antioxidant potential activity of theaflavins and catechins, in tea, presented the following order: theaflavin-3,3′-digallate > (-)-epicatechin gallate ≥ (-)-epigallocatechin gallate ≥ theaflavin-3′-gallate ≥ theaflavin-3-gallate > theaflavin ≥ (-)-epicatechin > (-)-epicatechin gallate, in decreasing order using human LDL (Low-Density-Lipoprotein cholesterol) as the oxidation model. When, they compared their work with the former study by Yoshino and collaborators [27] (who showed, in rat liver homogenates, that both green and black tea infusions had similar antioxidant activities), they concluded that the theaflavins present in black tea have similar antioxidant potency as the catechins present in green tea.

Leung and co-workers[24] demonstrated that the antioxidant potential activity of theaflavins and catechins, in tea, presented the following order: theaflavin-3,3′-digallate > (-)-epicatechin gallate ≥ (-)-epigallocatechin gallate ≥ theaflavin-3′-gallate ≥ theaflavin-3-gallate > theaflavin ≥ (-)-epicatechin > (-)-epicatechin gallate, in decreasing order using human LDL (Low-Density-Lipoprotein cholesterol) as the oxidation model. When, they compared their work with the former study by Yoshino and collaborators[27] (who showed, in rat liver homogenates, that both green and black tea infusions had similar antioxidant activities), they concluded that the theaflavins present in black tea have similar antioxidant potency as the catechins present in green tea.

Being rich in natural antioxidants, are assigned to tea and herbal infusions anticariogenic properties, anti-microbial and anti-cancerous activity [7]. These beverages also offer beneficial properties against kidney stones [28], dental caries [29], maintain bone mineral density [30], can be used to treat malaria and high blood pressure [31], cough, stomach pain, fever [32], diarrhea [33] besides acting as tranquilizers [34]. However, Massey [35] reports that tea consumption may increase the formation of calcium oxalate stones and advise those prone to calcium oxalate stone formation to lower levels of consumption.

Being rich in natural antioxidants, are assigned to tea and herbal infusions anticariogenic properties, anti-microbial and anti-cancerous activity[7] These beverages also offer beneficial properties against kidney stones[8], dental caries [29], maintain bone mineral density[30], can be used to treat malaria and high blood pressure [31], cough, stomach pain, fever[32], diarrhea[33] besides acting as tranquilizers [34]. However, Massey [35] reports that tea consumption may increase the formation of calcium oxalate stones and advise those prone to calcium oxalate stone formation to lower levels of consumption.

So, not only tea infusion is an important vehicle for introducing health-promoting compounds into our diet, but also, herbal infusions/tisanes become increasingly popular as part of a well-balanced diet by its medicinal properties.

  1. Izzo, A.A.; Hoon-Kim, S.; Radhakrishnan, R.; Williamson, E.M. A critical approach to evaluating clinical efficacy, adverse events and drug interactions of herbal remedies. Phytother Res. 2016, 30(5), 691–700. https://doi.org/10.1002/ptr.5591
  2. Taylor S. Tea Types, Production, and Trade. In Encyclopedia of Food Science and Nutrition, 2nd ed; Caballero, B.; Finglas, P.; Toldra, F Eds., Academic Press, 2003; pp. 5737-5743. ISBN: 9780122270550
  3. Jäger, S.; Beffert, M.; Hoppe, K.; Nadberezny, D.; Frank, B.; Scheffler, A. Preparation of Herbal Tea as Infusion or by Maceration at Room Temperature Using Mistletoe Tea as an Example. Sci Pharm. 2011, 79(1), 145-155. doi: 10.3797/scipharm.1006-06.
  4. Guimarães, R.; Barros, L.; Carvalho, A.M.; Ferreira, I.C. Infusions and Decoctions of Mixed Herbs used in Folk Medicine: Synergism in Antioxidant Potential. Phytother. Res. 2011, 25, 1209–1214. [CrossRef] [PubMed].
  5. Malik, J.; Szakova, J.; Drabek, O.; Balik, J.; Kokoska, L. Determination of Certain Micro and Macroelements in Plant Stimulants and Their Infusions. Food Chem. 2008, 111, 520–525. [CrossRef] [PubMed]
  1. Forest & Kim Starr-Jardim Botânico UTAD. Available online: https://jb.utad.pt/fotografia/Camellia_sinensis. 2a244676b03172250ab320.pq.jpg (accessed on 5 May 2019).
  2. Soni, R.P.; Katoch, M.; Kumar, A.; Ladohiya, R.; Verma, P. Tea: Production, Composition, Consumption and It’s Potential as an Antioxidant and Antimicrobial Agent. Int. J. Food Ferment. Technol. 2015, 5, 95–106. [CrossRef]
  3. Wang, C.; Lv, S.; Wu, Y.; Gao, X.; Li, J.; Zhang, W.; Meng, O. Oolong tea made from tea plants from dierent locations in Yunnan and Fujian, China showed similar aroma but dierent taste characteristics. SpringerPlus 2016, 5, 576. [CrossRef] [PubMed]
  4. Sinija, V.R.; Mishra, H.N. Green tea: Health benefits, Review. J. Nutr. Environ. Med. 2008, 17, 232–242. [CrossRef]
  5. Lv, H.-P.; Dai,W.-D.; Tan, J.-F.; Guo, L.; Zhu, Y.; Lin, Z. Identification of the anthocyanins from the purple leaf colored tea cultivar Zijuan (Camellia sinensis var. assamica) and characterization of their antioxidant activities. J. Funct. Foods 2015, 17, 449–458. [CrossRef]
  6. Lv, S.D.;Wu, Y.S.; Li, C.; Xu, Y.; Liu, L.; Meng, Q.X. Comparative analysis of Pu-erh and Fuzhuan teas by fully automatic headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry and chemometric methods. J. Agric. Food Chem. 2014, 62, 1810–1818. [CrossRef]
  7. Banerjee, R.; Bandyopadhyay, R.; Tudu, B.; Bhattacharyya, N. Tea and the Use of the Electronic Nose. In Electronic Noses and Tongues in Food Science; Méndez, M.L.R., Ed.; Academic Press: Cambridge, MA, USA, 2016; Chapter 13; pp. 125–135, ISBN 9780128002438. [CrossRef]
  8. Yang, C.S.; Maliakal, P.; Meng, X. Inhibition of carcinogenesis by tea. Annu. Rev. Pharmacol. Toxicol. 2002, 42, 25–54. [CrossRef]
  9. Pou, K.R.J. Fermentation: The Key Step in the Processing of Black Tea. J. Biosyst. Eng. 2016, 41, 85–92. [CrossRef]
  10. Samanta, T.; Cheeni, V.; Das, S.; Roy, A.B.; Ghosh, B.C.; Mitra, A. Assessing biochemical changes during the standardization of fermentation time and temperature for manufacturing quality black tea. J. Food Sci. Technol. 2015, 52, 2387–2393. [CrossRef] [PubMed]
  11. Carloni, P.; Tiano, L.; Padella, L.; Bacchetti, T.; Customu, C.; Kay, A.; Damiani, E. Antioxidant activity of white, green and black tea obtained from the same tea cultivar. Food Res. Int. 2013, 53, 900–908. [CrossRef]
  12. Middleton, E.; Kandaswami, C.; Theoharis, T.C. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 2000, 52, 673–751. [PubMed]
  13. Balasundram, N.; Sundram, K.; Samman, S. Phenolic compounds in plants and agri-industrial by-products: Antioxidant activity, occurrence, and potential uses. Food Chem. 2006, 99, 191–203. [CrossRef]
  14. Herrera, T.; Aguilera, Y.; Rebollo-Hernanza, M.; Bravoa, E.; Beníteza, V.; Martínez-Sáezb, N.; Arribasc, S.M.; Castillo, M.D.; Martín-Cabrejasa, M.A. Teas and herbal infusions as sources of melatonin and other bioactive non-nutrient components. LWT 2018, 89, 65–73. [CrossRef]
  15. Lee, J.; Chambers, D.H. A lexicon for flavor descriptive analysis of green tea. J. Sens. Stud. 2007, 22, 256–272. [CrossRef]
  16. Khokhar, S.; Magnusdottir, S.G.M. Total phenol, catechin, and caffeine contents of teas commonly consumed in the United Kingdom. J. Agric. Food Chem. 2002, 50, 565–570. [CrossRef]
  17. Byun, J.-O.; Han, J.-S. A study perception and actual status of utilization for green tea. J. Korean Soc. Food Cult. 2004, 19, 184–192.
  18. Dhalla, N.S.; Temsah, R.M.; Netticadan, T. Role of oxidative stress in cardiovascular diseases. J. Hypertens. 2000, 18, 655–673. [CrossRef]
  19. Leung, L.K.; Su, Y.; Chen, R.; Zhang, Z.; Huang, Y.; Chen, Z.-U. Theaflavins in Black Tea and Catechins in Green Tea Are Equally Effective Antioxidants. J. Nutr. 2001, 131, 2248–2251. [CrossRef] [PubMed]
  20. Rice-Evans, C. Implications of the mechanisms of action of tea polyphenols as antioxidants in vitro for chemoprevention in humans. Proc. Soc. Exp. Biol. Med. 1999, 220, 262–266. [CrossRef] [PubMed]
  21. Atoui, A.K.; Mansouri, A.; Boskou, G.; Kefalas, P. Tea, and herbal infusions: Their antioxidant activity and phenolic profile. Food Chem. 2005, 89, 27–36. [CrossRef]
  22. Yoshino, K.; Hara, Y.; Sano, M.; Tomita, S. Antioxidative effects of black tea theaflavins and thearubigin on lipid peroxidation of rat liver homogenates induced by tert-butyl hydroperoxide. Biol. Pharm. Bull. 1994, 17, 146–149. [CrossRef] [PubMed]
  23. Borghi, L.; Meschi, T.; Schianchi, T.; Briganti, A.; Guerra, A.; Allegri, F.; Novarini, A. Urine volume: Stone risk factor and preventive measure. Nephron 1999, 81 (Suppl. 1), 31–37. [CrossRef] [PubMed]
  24. Simpson, A.; Shaw, L.; Smith, A.J. The bio-availability of Fluoride from black tea. J. Dent. Oral Biol. 2001, 29, 15–21. [CrossRef]
  25. Hegarty, V.M.; May, H.M.; Khaw, K.T. Tea drinking and bone mineral density in older women. Am. J. Clin. Nutr. 2000, 71, 1003–1007. [CrossRef]
  26. Pascual, M.E.; Slowing, K.; Carretero, E.; Sánchez, D.M.; Villar, A. Lippia: Traditional Uses, Chemistry, and Pharmacology: A Review. J. Ethnopharmacol. 2001, 76, 201–214. [CrossRef]
  27. Kerharo, M.; Adam, A. La Pharmacopée Sénégalaise Traditionnelle—Plantes Médicinales Et Toxiques; Vigot: Paris, France, 1974; 778p, ISBN 2-7114-0646-6.
  28. Ouedraogo, O.G. PlantesMédicinales et PratiquesMédicales Traditionnelles du Burkina Faso: Cas du Plateau Central. Thèse de l’Université de Ouagadougou, Université de Ouagadougou, Ouagadougou, Burkina Faso, 1986; 261p.
  29. Abena, A.A.; Diatewa, M.; Gakossi, G.; Gbeassor, M.; Hondi-Assah, T.H.; Ouamba, J.M. Analgesic, Antipyretic and Anti-Inflammatory Effects of Essential oil of Lippia multiflora. Fitoterapia 2003, 74, 231–236. [CrossRef]
  30. Massey, L.K. Dietary Influences on Urinary Oxalate and Risk of Kidney Stones. Front. Biosci. 2003, 8, s584–s594. [CrossRef]

So, not only tea infusion is an important vehicle for introducing health-promoting compounds into our diet, but also, herbal infusions/tisanes become increasingly popular as part of a well-balanced diet by its medicinal properties.

This publication can be found here: https://doi.org/10.3390/beverages5030048

References

  1. Izzo, A.A.; Hoon-Kim, S.; Radhakrishnan, R.; Williamson, E.M. A critical approach to evaluating clinical efficacy, adverse events and drug interactions of herbal remedies. Phytother Res. 2016, 30(5), 691–700. https://doi.org/10.1002/ptr.5591
  2. Taylor S. Tea Types, Production, and Trade. In Encyclopedia of Food Science and Nutrition, 2nd ed; Caballero, B.; Finglas, P.; Toldra, F Eds., Academic Press, 2003; pp. 5737-5743. ISBN: 9780122270550
  3. Jäger, S.; Beffert, M.; Hoppe, K.; Nadberezny, D.; Frank, B.; Scheffler, A. Preparation of Herbal Tea as Infusion or by Maceration at Room Temperature Using Mistletoe Tea as an Example. Sci Pharm. 2011, 79(1), 145-155. doi: 10.3797/scipharm.1006-06.
  4. Guimarães, R.; Barros, L.; Carvalho, A.M.; Ferreira, I.C. Infusions and Decoctions of Mixed Herbs used in Folk Medicine: Synergism in Antioxidant Potential. Phytother. Res. 2011, 25, 1209–1214. .
  5. Malik, J.; Szakova, J.; Drabek, O.; Balik, J.; Kokoska, L. Determination of Certain Micro and Macroelements in Plant Stimulants and Their Infusions. Food Chem. 2008, 111, 520–525.
  6. Forest & Kim Starr-Jardim Botânico UTAD. Available online: https://jb.utad.pt/fotografia/Camellia_sinensis. 2a244676b03172250ab320.pq.jpg (accessed on 5 May 2019).
  7. Soni, R.P.; Katoch, M.; Kumar, A.; Ladohiya, R.; Verma, P. Tea: Production, Composition, Consumption and It’s Potential as an Antioxidant and Antimicrobial Agent. Int. J. Food Ferment. Technol. 2015, 5, 95–106.
  8. Wang, C.; Lv, S.; Wu, Y.; Gao, X.; Li, J.; Zhang, W.; Meng, O. Oolong tea made from tea plants from dierent locations in Yunnan and Fujian, China showed similar aroma but dierent taste characteristics. SpringerPlus 2016, 5, 576.
  9. Sinija, V.R.; Mishra, H.N. Green tea: Health benefits, Review. J. Nutr. Environ. Med. 2008, 17, 232–242.
  10. Lv, H.-P.; Dai,W.-D.; Tan, J.-F.; Guo, L.; Zhu, Y.; Lin, Z. Identification of the anthocyanins from the purple leaf colored tea cultivar Zijuan (Camellia sinensis var. assamica) and characterization of their antioxidant activities. J. Funct. Foods 2015, 17, 449–458.
  11. Lv, S.D.;Wu, Y.S.; Li, C.; Xu, Y.; Liu, L.; Meng, Q.X. Comparative analysis of Pu-erh and Fuzhuan teas by fully automatic headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry and chemometric methods. J. Agric. Food Chem. 2014, 62, 1810–1818.
  12. Banerjee, R.; Bandyopadhyay, R.; Tudu, B.; Bhattacharyya, N. Tea and the Use of the Electronic Nose. In Electronic Noses and Tongues in Food Science; Méndez, M.L.R., Ed.; Academic Press: Cambridge, MA, USA, 2016; Chapter 13; pp. 125–135, ISBN 9780128002438.
  13. Yang, C.S.; Maliakal, P.; Meng, X. Inhibition of carcinogenesis by tea. Annu. Rev. Pharmacol. Toxicol. 2002, 42, 25–54.
  14. Pou, K.R.J. Fermentation: The Key Step in the Processing of Black Tea. J. Biosyst. Eng. 2016, 41, 85–92.
  15. Samanta, T.; Cheeni, V.; Das, S.; Roy, A.B.; Ghosh, B.C.; Mitra, A. Assessing biochemical changes during the standardization of fermentation time and temperature for manufacturing quality black tea. J. Food Sci. Technol. 2015, 52, 2387–2393.
  16. Carloni, P.; Tiano, L.; Padella, L.; Bacchetti, T.; Customu, C.; Kay, A.; Damiani, E. Antioxidant activity of white, green and black tea obtained from the same tea cultivar. Food Res. Int. 2013, 53, 900–908.
  17. Middleton, E.; Kandaswami, C.; Theoharis, T.C. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 2000, 52, 673–751.
  18. Balasundram, N.; Sundram, K.; Samman, S. Phenolic compounds in plants and agri-industrial by-products: Antioxidant activity, occurrence, and potential uses. Food Chem. 2006, 99, 191–203.
  19. Herrera, T.; Aguilera, Y.; Rebollo-Hernanza, M.; Bravoa, E.; Beníteza, V.; Martínez-Sáezb, N.; Arribasc, S.M.; Castillo, M.D.; Martín-Cabrejasa, M.A. Teas and herbal infusions as sources of melatonin and other bioactive non-nutrient components. LWT 2018, 89, 65–73.
  20. Lee, J.; Chambers, D.H. A lexicon for flavor descriptive analysis of green tea. J. Sens. Stud. 2007, 22, 256–272.
  21. Khokhar, S.; Magnusdottir, S.G.M. Total phenol, catechin, and caffeine contents of teas commonly consumed in the United Kingdom. J. Agric. Food Chem. 2002, 50, 565–570.
  22. Byun, J.-O.; Han, J.-S. A study perception and actual status of utilization for green tea. J. Korean Soc. Food Cult. 2004, 19, 184–192.
  23. Dhalla, N.S.; Temsah, R.M.; Netticadan, T. Role of oxidative stress in cardiovascular diseases. J. Hypertens. 2000, 18, 655–673.
  24. Leung, L.K.; Su, Y.; Chen, R.; Zhang, Z.; Huang, Y.; Chen, Z.-U. Theaflavins in Black Tea and Catechins in Green Tea Are Equally Effective Antioxidants. J. Nutr. 2001, 131, 2248–2251.
  25. Rice-Evans, C. Implications of the mechanisms of action of tea polyphenols as antioxidants in vitro for chemoprevention in humans. Proc. Soc. Exp. Biol. Med. 1999, 220, 262–266.
  26. Atoui, A.K.; Mansouri, A.; Boskou, G.; Kefalas, P. Tea, and herbal infusions: Their antioxidant activity and phenolic profile. Food Chem. 2005, 89, 27–36.
  27. Yoshino, K.; Hara, Y.; Sano, M.; Tomita, S. Antioxidative effects of black tea theaflavins and thearubigin on lipid peroxidation of rat liver homogenates induced by tert-butyl hydroperoxide. Biol. Pharm. Bull. 1994, 17, 146–149.
  28. Borghi, L.; Meschi, T.; Schianchi, T.; Briganti, A.; Guerra, A.; Allegri, F.; Novarini, A. Urine volume: Stone risk factor and preventive measure. Nephron 1999, 81 (Suppl. 1), 31–37.
  29. Simpson, A.; Shaw, L.; Smith, A.J. The bio-availability of Fluoride from black tea. J. Dent. Oral Biol. 2001, 29, 15–21.
  30. Hegarty, V.M.; May, H.M.; Khaw, K.T. Tea drinking and bone mineral density in older women. Am. J. Clin. Nutr. 2000, 71, 1003–1007.
  31. Pascual, M.E.; Slowing, K.; Carretero, E.; Sánchez, D.M.; Villar, A. Lippia: Traditional Uses, Chemistry, and Pharmacology: A Review. J. Ethnopharmacol. 2001, 76, 201–214.
  32. Kerharo, M.; Adam, A. La Pharmacopée Sénégalaise Traditionnelle—Plantes Médicinales Et Toxiques; Vigot: Paris, France, 1974; 778p, ISBN 2-7114-0646-6.
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