Various Protein Kinase Inhibitors as Anticancer Agents: Comparison
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Please note this is a comparison between Version 2 by Conner Chen and Version 1 by Aleksandra Sochacka-Ćwikła.

Protein kinases (PTKs) are enzymes that regulate the biological activity of proteins by phosphorylation of certain amino acid residues. This reaction causes a conformational change from an inactive to an active form of the protein, which is one of the most important regulatory mechanisms of the cell cycle and transduction of external signals. Dysregulation of protein kinases activity is implicated in the processes of carcinogenesis and the progression of various solid cancers. Therefore, protein kinases are prime targets for the development of selective anticancer drugs.

  • Protein kinases
  • Anticancer agents
  • Small molecule inhibitors
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