IncrTheased gut permeability is suggested to be involved in the pathogenesis of a growing number of disorders. The altered intestinal barrier consists of the mucus layer, intestinal barrier and the subsequent translocation of bacteria or bacterial products into the internal milieu of the human body induce the inflammatory state. Gut microbiotamicrobiota, intestinal epithelial cells (IECs) and lamina propria. In the context of maintains intestinal epitheliuming the integrity. Since dysbiosis contributes to increased gut permeability, the interventions that change the gut of the intestinal barrier, intestinal epithelial cells and microbiota and correct dysbiosis are suggested to also restore intestinal barrier functionre essential.