Non-Invasive Sweat Diagnostics Wearable Biosensors: Comparison
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Please note this is a comparison between Version 2 by Conner Chen and Version 1 by Jun Chen.

Wearable bioelectronics has received tremendous attention worldwide due to its great a potential for predictive medical modeling and allowing for personalized point-of-care-testing (POCT). Since the distribution of sweat glands in the human body is rich (>100 glands/cm2) and the sweat contains abundant biochemical compounds, human sweat has become a promising bio-fluid for non-invasive biosensing. Since nearly every portion of human skin has eccrine glands, sweat is readily available without the use of needles or other invasive devices. Iontophoresis sweat can be extracted from anywhere which is not possible in any other case of bio-fluids. Moreover, analytes including ions, metabolites, acids, hormones, and small proteins and peptides are partitioned into the sweat. Sweat also contains various electrolytes (such as potassium, sodium, chloride, and calcium), nitrogen-containing compounds (such as urea and amino acids), as well as metabolites such as glucose, lactic acid, and uric acid, along with xenobiotics such as drugs and ethanol.

  • point-of-care
  • biomonitoring
  • personalized healthcare
  • sweat
  • biosensors
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References

  1. Yang, Y.; Gao, W. Wearable and Flexible Electronics for Continuous Molecular Monitoring. Chem. Soc. Rev. 2018, 48, 1465–1491.
  2. Gao, W.; Emaminejad, S.; Nyein, H.Y.; Challa, S.; Chen, K.; Peck, A.; Fahad, H.M.; Ota, H.; Shiraki, H.; Kiriya, D.; et al. Fully Integrated Wearable Sensor Arrays for Multiplexed in Situ Perspiration Analysis. Nature 2016, 529, 509–514.
  3. Schazmann, B.; Morris, D.; Slater, C.; Beirne, S.; Fay, C.; Reuveny, R.; Moyna, N.; Diamond, D. A Wearable Electrochemical Sensor for the Real-Time Measurement of Sweat Sodium Concentration. Anal. Methods 2010, 2, 342.
  4. Emaminejad, S.; Gao, W.; Wu, E.; Davies, Z.A.; Yin Yin Nyein, H.; Challa, S.; Ryan, S.P.; Fahad, H.M.; Chen, K.; Shahpar, Z.; et al. Autonomous Sweat Extraction and Analysis Applied to Cystic Fibrosis and Glucose Monitoring Using a Fully Integrated Wearable Platform. Proc. Natl. Acad. Sci. USA 2017, 114, 4625–4630.
  5. Patterson, M.J.; Galloway, S.D.R.; Nimmo, M.A. Variations in Regional Sweat Composition in Normal Human Males. Exp. Physiol. 2000, 85, 869–875.
  6. Nyein, H.Y.; Gao, W.; Shahpar, Z.; Emaminejad, S.; Challa, S.; Chen, K.; Fahad, H.M.; Tai, L.C.; Ota, H.; Davis, R.W.; et al. A Wearable Electrochemical Platform for Noninvasive Simultaneous Monitoring of Ca2+ and Ph. ACS Nano 2016, 10, 7216–7224.
  7. Anastasova, S.; Crewther, B.; Bembnowicz, P.; Curto, V.; Ip, H.M.; Rosa, B.; Yang, G.Z. A Wearable Multisensing Patch for Continuous Sweat Monitoring. Biosens. Bioelectron. 2017, 93, 139–145.
  8. Guinovart, T.; Bandodkar, A.J.; Windmiller, J.R.; Andrade, F.J.; Wang, J. A Potentiometric Tattoo Sensor for Monitoring Ammonium in Sweat. Analyst 2013, 138, 7031–7038.
  9. Kim, J.; de Araujo, W.R.; Samek, I.A.; Bandodkar, A.J.; Jia, W.; Brunetti, B.; Paixão, T.R.L.C.; Wang, J. Wearable Temporary Tattoo Sensor for Real-Time Trace Metal Monitoring in Human Sweat. Electrochem. Commun. 2015, 51, 41–45.
  10. Gao, W.; Nyein, H.Y.Y.; Shahpar, Z.; Fahad, H.M.; Chen, K.; Emaminejad, S.; Gao, Y.; Tai, L.-C.; Ota, H.; Wu, E.; et al. Wearable Microsensor Array for Multiplexed Heavy Metal Monitoring of Body Fluids. ACS Sens. 2016, 1, 866–874.
  11. Tai, L.C.; Liaw, T.S.; Lin, Y.; Nyein, H.Y.Y.; Bariya, M.; Ji, W.; Hettick, M.; Zhao, C.; Zhao, J.; Hou, L.; et al. Wearable Sweat Band for Noninvasive Levodopa Monitoring. Nano Lett. 2019, 19, 6346–6351.
  12. Tai, L.C.; Gao, W.; Chao, M.; Bariya, M.; Ngo, Q.P.; Shahpar, Z.; Nyein, H.Y.Y.; Park, H.; Sun, J.; Jung, Y.; et al. Methylxanthine Drug Monitoring with Wearable Sweat Sensors. Adv. Mater. 2018, 30, e1707442.
  13. Sonner, Z.; Wilder, E.; Heikenfeld, J.; Kasting, G.; Beyette, F.; Swaile, D.; Sherman, F.; Joyce, J.; Hagen, J.; Kelley-Loughnane, N.; et al. The Microfluidics of the Eccrine Sweat Gland, Including Biomarker Partitioning, Transport, and Biosensing Implications. Biomicrofluidics 2015, 9, 031301.
  14. Kim, J.; Jeerapan, I.; Imani, S.; Cho, T.N.; Bandodkar, A.; Cinti, S.; Mercier, P.P.; Wang, J. Noninvasive Alcohol Monitoring Using a Wearable Tattoo-Based Iontophoretic-Biosensing System. ACS Sens. 2016, 1, 1011–1019.
  15. Abellan-Llobregat, A.; Jeerapan, I.; Bandodkar, A.; Vidal, L.; Canals, A.; Wang, J.; Morallon, E. A Stretchable and Screen-Printed Electrochemical Sensor for Glucose Determination in Human Perspiration. Biosens. Bioelectron. 2017, 91, 885–891.
  16. Windmiller, J.R.; Bandodkar, A.J.; Valdes-Ramirez, G.; Parkhomovsky, S.; Martinez, A.G.; Wang, J. Electrochemical Sensing Based on Printable Temporary Transfer Tattoos. Chem. Commun. 2012, 48, 6794–6796.
  17. Munje, R.D.; Muthukumar, S.; Panneer Selvam, A.; Prasad, S. Flexible Nanoporous Tunable Electrical Double Layer Biosensors for Sweat Diagnostics. Sci. Rep. 2015, 5, 14586.
  18. Kinnamon, D.; Ghanta, R.; Lin, K.C.; Muthukumar, S.; Prasad, S. Portable Biosensor for Monitoring Cortisol in Low-Volume Perspired Human Sweat. Sci. Rep. 2017, 7, 13312.
  19. Shields, J.B.; Johnson, B.C.; Hamilton, T.S.; Mitchell, H.H. The Excretion of Ascorbic Acid and Dehydroascorbic Acid in Sweat and Urine under Different Environmental Conditions. J. Biol. Chem. 1945, 161, 351–356.
  20. Kim, B.-Y.; Lee, H.-B.; Lee, N.-E. A Durable, Stretchable, and Disposable Electrochemical Biosensor on Three-Dimensional Micro-Patterned Stretchable Substrate. Sens. Actuators B 2019, 283, 312–320.
  21. Mannoor, M.S.; Tao, H.; Clayton, J.D.; Sengupta, A.; Kaplan, D.L.; Naik, R.R.; Verma, N.; Omenetto, F.G.; McAlpine, M.C. Graphene-Based Wireless Bacteria Detection on Tooth Enamel. Nat. Commun. 2012, 3, 763.
  22. Lee, H.; Song, C.; Hong, Y.S.; Kim, M.S.; Cho, H.R.; Kang, T.; Shin, K.; Choi, S.H.; Hyeon, T.; Kim, D.H. Wearable/Disposable Sweat-Based Glucose Monitoring Device with Multistage Transdermal Drug Delivery Module. Sci. Adv. 2017, 3, e1601314.
  23. Song, Y.; Min, J.; Yu, Y.; Wang, H.; Yang, Y.; Zhang, H.; Gao, W. Wireless Battery-Free Wearable Sweat Sensor Powered by Human Motion. Sci. Adv. 2020, 6, eaay9842.
  24. Peng, Z.; Song, J.; Gao, Y.; Liu, J.; Lee, C.; Chen, G.; Wang, Z.; Chen, J.; Leung, M.K.H. A Fluorinated Polymer Sponge with Superhydrophobicity for High-Performance Biomechanical Energy Harvesting. Nano Energy 2021, 85, 106021.
  25. Zou, Y.; Raveendran, V.; Chen, J. Wearable Triboelectric Nanogenerators for Biomechanical Energy Harvesting. Nano Energy 2020, 77, 105303.
  26. Zou, Y.; Xu, J.; Chen, K.; Chen, J. Advances in Nanostructures for High-Performance Triboelectric Nanogenerators. Adv. Mater. Technol. 2021, 6, 2000916.
  27. Zhou, Y.; Deng, W.; Xu, J.; Chen, J. Engineering Materials at the Nanoscale for Triboelectric Nanogenerators. Cell Rep. Phys. Sci. 2020, 1, 100142.
  28. Deng, W.; Zhou, Y.; Zhao, X.; Zhang, S.; Zou, Y.; Xu, J.; Yeh, M.H.; Guo, H.; Chen, J. Ternary Electrification Layered Architecture for High-Performance Triboelectric Nanogenerators. ACS Nano 2020, 14, 9050–9058.
  29. Chu, X.; Zhao, X.; Zhou, Y.; Wang, Y.; Han, X.; Zhou, Y.; Ma, J.; Wang, Z.; Huang, H.; Xu, Z.; et al. An Ultrathin Robust Polymer Membrane for Wearable Solid-State Electrochemical Energy Storage. Nano Energy 2020, 76, 105179.
  30. Xu, J.; Zou, Y.; Nashalian, A.; Chen, J. Leverage Surface Chemistry for High-Performance Triboelectric Nanogenerators. Front. Chem. 2020, 8, 577327.
  31. Bakker, E.; Pretsch, E. Potentiometric Sensors for Trace-Level Analysis. Trends Analyt. Chem. 2005, 24, 199–207.
  32. Terse-Thakoor, T.; Punjiya, M.; Matharu, Z.; Lyu, B.; Ahmad, M.; Giles, G.E.; Owyeung, R.; Alaimo, F.; Shojaei Baghini, M.; Brunyé, T.T.; et al. Thread-Based Multiplexed Sensor Patch for Real-Time Sweat Monitoring. NPJ Flexible Electron. 2020, 4, 1–10.
  33. Meng, K.; Zhao, S.; Zhou, Y.; Wu, Y.; Zhang, S.; He, Q.; Wang, X.; Zhou, Z.; Fan, W.; Tan, X.; et al. A Wireless Textile-Based Sensor System for Self-Powered Personalized Health Care. Matter 2020, 2, 896–907.
  34. Karbelkar, A.A.; Furst, A.L. Electrochemical Diagnostics for Bacterial Infectious Diseases. ACS Infect. Dis. 2020, 6, 1567–1571.
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