Sources of HM Contamination in Arable Lands: Comparison
View Latest Version
Please note this is a comparison between Version 2 by Conner Chen and Version 1 by Abdur Rashid.

Heavy metals and metalloids (HMs) are environmental pollutants, most notably cadmium, lead, arsenic, mercury, and chromium. When HMs accumulate to toxic levels in agricultural soils, these non-biodegradable elements adversely affect crop health and productivity. The toxicity of HMs on crops depends upon factors including crop type, growth condition, and developmental stage; nature of toxicity of the specific elements involved; soil physical and chemical properties; occurrence and bioavailability of HM ions in the soil solution; and soil rhizosphere chemistry. HMs can disrupt the normal structure and function of cellular components and impede various metabolic and developmental processes. 

  • heavy metals
  • arable lands
  • agricultural practices

1. Introduction

Metals, including potentially toxic elements, are inorganic elements containing atomic densities (g·cm−3) several times higher than H2O (1 g·cm−3) and broadly classified into heavy and light metals, and semi-metals (Figure 1). Based on physical, physiological, and chemical properties, metals have been classified under several sub-groups, namely: transition metals: e.g., chromium (Cr), manganese (Mn), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), and molybdenum (Mo); post-transition metals: e.g., aluminum (Al), zinc (Zn), cadmium (Cd), mercury (Hg), and lead (Pb); alkaline earth metals: e.g., calcium (Ca), magnesium (Mg), beryllium (Be), and barium (Ba); alkali metals: e.g., lithium (Li), sodium (Na), potassium (K), and cesium (Cs); and metalloids, which are also referred to as semi-metals because of their metallic and non-metallic properties: e.g., boron (B), silicon (Si), arsenic (As), and antimony (Sb) [1].
Agronomy 13 01521 g001 550
Figure 1. Classification of metallic and non-metallic elements frequently found in agricultural soils. Mg (magnesium), Ca (calcium), Fe (iron), B (boron), Mn (manganese), Zn (zinc), Mo (molybdenum), Cu (copper), Pb (lead), Ni (nickel), Cr (chromium), As (arsenic), Hg (mercury), Cd (cadmium), Al (aluminum), Li (lithium), K (potassium), Na (sodium), Si (silicon).
Heavy metals and metalloids (HMs) are environmental pollutants. They are also agricultural soil contaminants, because if present at elevated levels in the soil, HMs can negatively impact crop health and productivity [2,3][2][3]. HMs are recalcitrant to degradation, and if not taken up by plants or removed by leaching, they can accumulate in the soil and persist for long periods [4,5,6][4][5][6]. The elements that are frequently found to contaminate agricultural soils and cause toxic effects at elevated levels on plants include Cd, Pb, Cr, As, Hg, Ni, Cu, and Zn [4,7][4][7]. Among them, Cd, Pb, As, Hg, and Cr are highly toxic and detrimental to plant health at almost all levels of contamination [8,9,10][8][9][10].
Several elements are classified as essential mineral nutrients for plant growth and productivity (Figure 1). Examples include Cu, Zn, Fe, Mn, Mo, Ni, Mg, Ca, and B. At relatively low concentrations, these elements can enhance specific cellular functions in plants including ion homeostasis, pigment biosynthesis, photosynthesis, respiration, enzyme activities, gene regulation, sugar metabolism, nitrogen fixation, etc. [3,8,11][3][8][11]. However, when accumulated at concentrations above optimum, these same essential elements can adversely affect plant growth, development, and reproduction [2,3][2][3]. Conversely, if the concentration falls below certain threshold levels, they also produce mineral deficiency symptoms in plants [11].
HM contamination in agricultural soil is a global issue. In addition to certain geogenic and climatic factors, specific circumstances such as rapid urbanization, and increased industrial, municipal, agricultural, domestic, medical, and technological applications appear to be the major causes of HM pollution in the environment at the present time. However, the problem is more prominent in many developing countries, partly because of the above reasons, and perhaps partly due to a lack of proper awareness about the toxic consequences of these elements not only to human health but also to crop health [12,13,14,15,16][12][13][14][15][16].

2. Sources of HM Contamination in Arable Lands

Agricultural soil is an important non-renewable natural resource. It can be contaminated with toxic HM elements such as Cd, Pb, Cr, As, Hg, Cu, Ni, Zn, Al, and several others due to natural causes as well as anthropogenic activities. Natural causes include, among many others, weathering of metal-bearing rocks by rainwater and atmospheric deposition. Anthropogenic activities include industrial activities (e.g., mining, leather tanning, textile, and petrol-chemical), disposal of metal-containing wastes, vehicle exhausts, and agricultural practices [4,15,17,18,19,20][4][15][17][18][19][20]. However, irrespective of the source of contamination, continued addition of HMs to arable lands can result in soils that can be too toxic to support plant growth and productivity.

2.1. Application of Chemical Fertilizers

Chemical fertilizers, particularly inorganic fertilizers, are a crucial input for crop production. Consequently, large quantities of inorganic fertilizers, including nitrogen (N), phosphorus (P), potassium (K), and compound/mixed fertilizers are routinely added to agricultural lands to supply adequate quantities of these macronutrients. For instance, it was estimated that in 2019, more than 220 million tons of commercial fertilizers and liming materials were applied worldwide, mostly to agricultural fields [21]. Among these fertilizers, P fertilizers contain the highest level of HM contaminants [4,22,23,24][4][22][23][24]. For example, superphosphate fertilizers can contain Cd, Co, Cu, Pb, Zn, Cr, and Ni as contaminants. In a study that assessed soil with and without P fertilizer amendments, the concentration of Zn was higher not only in the amended soil, but also in the plants grown in that soil [25]. Cadmium content in the soil has been shown to increase persistently due to the application of P fertilizers [12,23,26][12][23][26]. Cadmium is extremely toxic to plants because of its high solubility and mobility in soil solution. The concentration of Cd present as an impurity in several P fertilizers evaluated in a study is shown in Table 1.
Table 1.
Cadmium concentrations in several phosphate fertilizers (adapted from [27]).
Fertilizers Cadmium Content (mg Kg−1)
  Based on Product Based on P Content
Complete fertilizer 23–29 418–527
Single superphosphate 16–26 186–302
Superphosphate 13–34 151–395
Rock phosphate 7.2–47 54–303
High analysis fertilizer <0.6–5.6 15–118
Double superphosphate <0.6–12 <3.6–72
Triple superphosphate 0.8–7.0 24–35
Mono-ammonium phosphate 1.8–8.1 12–37
Di-ammonium phosphate 4.3–6.6 22–28
In addition to P fertilizers, copper sulphate, iron sulphate, and zinc sulphate fertilizers can also contain HM contaminants, including Pb [22,27,28][22][27][28]. A study reported from greenhouse experiments that repeated application of chemical fertilizers significantly increased the accumulation of several HM elements in the soil (Table 2). Experiments carried out with soil samples collected from multiple locations in agricultural lands of peninsular Malaysia and Guangdong Province of China show that the concentrations of different HM elements (As, Cd, Co, Cr, Cu, Hg, Ni, Pb, Zn) were severalfold higher as compared to control soil samples (refer to Table S2). These HM elements have originated from suspected agricultural practices, including fertilizer applications. Sources of HM contamination in fertilizers include the raw materials used in the manufacture of inorganic fertilizers. For instance, phosphate rock, also known as phosphorite, is utilized in the production of P fertilizers [29,30][29][30]. Over 90% of potash extracted from mines is used in the manufacture of K fertilizer [31]. Based on the level of HM impurities, chemical fertilizers can be ranked as follows: P fertilizers ≥ compound fertilizers> K fertilizers> N fertilizer [32,33][32][33].
Table 2. Heavy metal concentrations in greenhouse soil because of repeated application of inorganic fertilizers (adapted from [24]).
Elements MAX MIN Fold Difference
  mg Kg−1 Soil  
Cd 0.65 0.06 10.8
Cu 171.5 21.0 8.2
Ni 36.9 28.7 1.3
Pb 38.0 20.5 1.9
Zn 433 71.9 6

2.2. Pesticide Application

Pesticides play an important role in global agriculture. It has been estimated that without pesticides, the world’s food production could be reduced by close to ~40% [34]. Another study estimated a 78% loss of fruit production, 54% loss of vegetable production, and 32% loss of cereal production without pesticide use [35]. Pesticides such as insecticides, fungicides, rodenticides, nematicides, and herbicides are composed of either organic or inorganic compounds that are toxic to the targeted organisms. Analysis of these compounds shows that some of them contain HM elements either as active ingredients (Table 3) or as impurities in the formulations (Table 4).
Table 3. Pesticides containing different HM elements in their active ingredients (adapted from [36,37]).
Pesticides containing different HM elements in their active ingredients (adapted from [36][37]).
Chemical Name Formula HM Elements
Insecticides    
Aluminum phosphide AIP Al
Lithium perfluorooctane sulfonate
C
8
F
17
LiO
3S Li
Sodium meta-arsenite NaAsO2 As
Fungicide    
Copper oxide CuO Cu
Mercuric chloride
HgCl
2
Hg
Table 4.
Pesticide products containing HM elements as impurities.
Trade Name Technical Name Metal Impurities (ppb) *
Insecticides   Defarge et al. [38]
Pyrinex® Chlorpyriphos As (390), Cr (800), Ni (1200)
Aluminum silicate Al2Si2O7 Al
Arsenic acid H3
Polysect® Acetamiprid Ni (50) AsO4 As
Copper bis(3-phenylsalicylate)
Fungicides   Copper acetoarsenite C4H6As6Cu4O16 As, Cu
Defarge et al., [38 Copper oxide Cu2O Cu
Copper carbonate CH2
C
26
H18CuO6 Cu
Copper abietate C40H58CuO4 Cu
Copper acetate Cu2(CH3COO)4 Cu
Copper carbonate CH2Cu2O Cu
Copper chloride
Cacodylic acid
Folpan® Folpet As (260), Cr (2000), Ni (1200)
(CH
3
)
2
AsO(OH)
As
]
Eyetak® Prochloraz As (200), Co (90), Cr (200), Ni (190), Pb (12) Cu2O Cu
Maronee® Tebuconazole As (90), Co (50), Cr (100) Copper naphthenate C22H14CuO4 Cu
Opus® Epoxiconazole Cr (90), Ni (60) Lead arsenate AsHO4Pb As, Pb
Pictor® Boscalid As (300), Co (275), Cr (1000), Ni (600) CuCl
Teldor® Fenhexamid As (575), Cr (800), Ni (800) 2
Herbicides   Cu
Defarge et al. [38]
R 3+® Glyphosate-based formulations As (375), Co (50), Cr (175), Ni (20)
R Bioforce® As (260), Cr (200), Ni (120)
R Express® As (60) Copper hydroxide
R GT+® As (450), Co (150), Cr (100), Ni (50), Pb (10) H2O2Cu Cu
Copper naphthenate C22H14CuO4 Cu
Copper oxychloride (ClCu2H3O3)2 Cu
Copper sulphate CuSO4-Ca(OH)2 Cu
Mercuric oxide HgO Hg
Mercurous chloride Hg2Cl2 Hg
Methoxyethylmercury chloride C3H7ClHgO Hg
As (75), Cr (250), Ni (100), Pb (100) Methoxyethylmercury acetate C5H10HgO3 Hg
Insecticides   Alnuwaiser [39] Phenyl mercuric acetate C8H
Sniper®8O2Hg Hg
Fipronil Zn (506), Cu (423), Cr (746), Co (275), Pb (88) Phenylmercury chloride C6H5ClHg Hg
CyperCel® Cypermethrin Zn (2389), Cu (669), Cr (373), Co (18), Pb (807) Phenylmercury nitrate C Rodenticides
R WeatherMax® As (500), Cr (100), Ni (20), Pb (10)
Bayer GC® As (75), Co (60), Cr, (110) Ni (20) 6H5HgNO3 Hg
CyperSafe® Cypermethrin Zn (968), Cu (464), Cr (10), Co (6), Pb (119) Sodium arsenite NaAsO2 As
Scope 60® Asaybrmthrin Zn (527), Cu (539), Cr (437), Co (23), Pb (39) Zinc borate ZnB3O
Brodor®4(OH)3 PermethrinZn, B
Zn (10), Cr (16), Pb (186)   
Clinic EV® As (400), Co (90), Cr (150), Ni (20)
ClashBarium carbonate BaCO
Glyfos® Zinc oxide ®ZnO Acephate + Buprofezin Zn (1078), Cr (73), Co (39), Pb (1316)
3 Ba
As (200), Cr (1100), Ni (50), Pb (30) Zn
Acefed® Mithomail Cu (19), Cr (48), Co (4), Pb (121)
Lanid® - Cu (128), Cr (60), Pb (98)
Probalt® - Cu (179), Cr (85), Co (25), Pb (46)
Nourcam® - -
Madar® - Zn (10), Cu (66), Cr (16), Co (10),
PifPaf® - Cu (110), Co (5), Thallium, Tl (19), Pb (12)
Paygon® - Zn (52), Tl (15), Pb (19)
* European Union (EU)/World Health Organization (WHO) prescribed permissible levels (ppb) in water: As (10), Cr (50), Ni (20/70), Pb (10), Co (NA).
Several fungicides and insecticides extensively used in the past in agricultural lands were shown to contain significant concentrations of HM elements in their active ingredients. Examples include Cu-containing fungicides such as copper sulphate (Bordeaux mixture, also referred to as Bordo® mix) and copper oxychloride; Pb-containing insecticide such as lead arsenate; and Cu-containing insecticide such as copper acetoarsenite. The commonly found HM elements in the active ingredients of pesticide products include Cu, As, Pb, Hg, Cr, Zn, Al, Li, Ba, B, and Ti (titanium) [36,37][36][37]. On the other hand, HM elements can also be present in pesticide products as impurities. For example, certain pesticide products used for pest control in Japan contained Cd, Hg, As, Cu, Zn, and Pb as contaminants [17]. A chemical analysis of several pesticides, including 11 glyphosate-based herbicide formulations, by utilizing inductively coupled plasma/optical emission spectrometry (ICP-OES) detected As, Cr, Co, Pb, and Ni as contaminants [38]. A similar analysis of several insecticides using ICP mass spectrometry detected Zn, Cu, Cr, Co, Pb, and Tl (thallium) as contaminants [39]. It has been suggested that the HM elements contaminate pesticide products during the manufacturing process, while some of them are intentionally added as nano pesticides for increased efficacy [38,40][38][40].

2.3. Application of Livestock Manures and Compost

Livestock manures are organic fertilizers composed predominantly of poultry, cattle, and pig manures. Application of these manures and the compost made from them to farmlands is a common practice in agricultural crop production. However, these manures and compost contain high concentrations of HM elements such as Cu, Zn, Cd, Ni, Cr, As, Pb, and Hg as contaminants [20,26,41,42][20][26][41][42]. A study conducted to determine the concentrations of HM elements in different livestock and poultry manures is presented in Table 5. The major sources of contamination of HM elements in the manures include the minerals supplied with the commercial feeds [41,42][41][42]. For example, supplementation of animal feeds with growth-promoting organic arsenical products was practiced for many years [43]. Some studies confirmed that Zn, Cu, As, and Cd were artificially added to commercial feeds to promote animal growth and improve disease resistance [44,45][44][45]. However, animals cannot digest these HM elements, and discharge them through manure [46]. Because HMs are non-degradable elements, they are also not broken down during the composting process [47]. Thus, long-term repeated applications of manures and compost can result in the buildup of HM elements to toxic levels in agricultural soil [48,49][48][49] and can affect crop health and productivity.
Table 5. A case study showing maximum (MAX) vs. minimum (MIN) concentration (mg Kg−1 dry weight) of HM elements in different livestock and poultry manures, and their fold differences (FD). (Adapted from [42]).
Source Level Zn Cu Pb Cd Cr Hg As Ni
0.2
0.6
1.2
FD
10
26
12
4.7
2.8 12 4.3 10

2.4. Application of Sewage-Sludge-Based Biosolids

Sewage sludge originated from municipal and industrial wastes can be highly contaminated with HM elements such as As, Cd, Cr, Cu, Pb, Hg, Ni, Mo, Zn, and others. Long-term application of untreated sewage sludge in some developing countries has led to increased concentrations of HMs in the agricultural lands [14,20,50][14][20][50]. However, the biosolids generated from sewage sludge processing plants can be typically low in HM contamination and can contain organic materials rich in nutrients, and be used as fertilizers [51,52][51][52]. When applied to arable lands, processed sewage sludge can improve soil physical properties and crop productivity. Utilization of these byproducts for agricultural crop production is, therefore, a common practice in many countries. In the United States, about 3.0 million dry tons of biosolids are utilized annually for crop production [4]. The European community countries utilized >30% of processed sewage sludge as a fertilizer in agricultural lands [53]. Australia incorporates over 175K tons of dry biosolids into agricultural soil [54]. In the United States, federal regulations limit concentrations of major elements (e.g., As, Cd, Cu, Pb, Hg, Ni, Se, and Zn) commonly found in biosolids for land application (Table 6) [52]. Although biosolids produced from sewage sludge processing treatment are generally low in HM concentration, repeated applications of these products can result in the buildup of HM elements in agricultural soil and can negatively impact crop health and productivity.
Table 6.
Regulatory limits for HM elements, commonly found in applied biosolids in the USA (adapted from [55]).
Elements Maximum Permissible Level (mg Kg−1) Cumulative Loading Rate (Kg ha−1) Monthly Average Concentrations (mg Kg−1) Annual Loading Rate (Kg ha−1)
Pig MAX 4639 1288 23 60
As 7585 (21.3)0.3 4189 19
41 2.0
4.62

(23.1) 15.20

(7.6)		 0.52

(5.2)		 0.02

(2.0)		 1.15

(0.2)		 - Ahmed et al. [16] MIN 100 73 0.3 0.04 3.5 Cd 85 39 39
Max level

(FD)		 0.94

(9.4)		0.0 0.01 4.7
0.61

1.9
(3.1) 0.86

(0.4) - 0.04

(4.0)		 0.19

(0.04)		 0.12

(0.6)		 Berihun et al. [58] FD 46 18 77 1500 24 - 8900 4.0
Cr 3000 3000 1200 150 Chicken MAX 578 314 33 4.1 251 0.5 23 39
Cu 4300 1500 1500 75 MIN 166 18 3.0 0.03 4.0 0.02 0.05 5.2
Pb 840 300 300 15 FD 3.5 17 11 137 63 25 460 7.5
Hg 57 17 17 0.9 Duck MAX 682 199 41 2.5 64 0.07 6.8 16
Ni 420 420 420 21 MIN 98 35 4.5 0.3 7.0 0.03 0.01 8.4
Se 100 100 36 5.0 FD 7.0 5.7 9.1 8.3 9.1 2.3 680 1.9
Zn 7500 2800 Poultry MAX 682 314 41 4.1 251 0.5 23 39
MIN 77 15 2.0 0.03 2.5 0.02 0.01 5.2
2800 140 FD 8.9 21 21 137 100 25 2300 7.5
Zineb
C
4
H
6
N
2
S
4
Zn
Zn
Herbicides
   
Arsenic acid H3AsO4 As
Calcium arsenate As2Ca3O8 As
Zinc phosphide
Zn
3P2 Zn
Thallium sulfate Tl2SO4
Glyphogan® As (320), Co (125), Cr (100), Ni (40)
Pavaprop-G® Cr (110), N (190)
Radical Tech+® As (270), Co (70), Cr (50), Ni (50)
Lonpar® 2,4-D As (160), Cr (150), Ni (180)
Matin® Isoproturon As (100), Cr (100), Ni (30), Pb (25)

2.5. Land Irrigation

The irrigation of agricultural lands with contaminated water from surface water bodies as well as groundwater sources is another route of HM contamination in agricultural soil. The above irrigation practices are more frequently followed in some developing countries [9,15,16,56,57][9][15][16][56][57]. A review of many related articles published in a span of over two decades (1994 to 2019) that determined the HM contamination in surface water bodies throughout the world showed that the average content of Cr, Mn, Co, Ni, As, and Cd exceeded the permissible limits as prescribed by the WHO and the United States EPA [9,20][9][20]. Studies conducted to determine HM concentrations in irrigation water in several locations of the Gazipur district of Bangladesh and the Gondar city of Ethiopia showed that in almost all tests, the concentration of HMs exceeded the FAO (Food and Agriculture Organization) prescribed admissible levels (Table 7).
Table 7.
HM concentrations in irrigation water reported in some studies as compared to FAO approved maximum permissible limits.
Elements Cr Cu Zn As Cd Pb Ni References
  mg L−1
Max level

(FD) *		 2.13

FAO limit
0.10 0.20 2.00 0.10 0.01 5.00 0.20  
Cattle
MAX
816
174
32 3.4 79 0.6 6.3 19
MIN 49 12 1.6 0.04 0.8 0.02 0.01 4.2
FD 17 15 20 85 99 30 630 4.5
Sheep MAX 431 215 20 1.4 22 2.4 2.6 12
MIN 42 8.4 1.7 0.3
Starane
®
Fluoroxypyr
Sodium arsenite
NaAsO
2
As
8.0
Tl
Defoliants
 
 
Sodium dichromate
Na2Cr2O7 Cr
Zinc chloride ZnCl2 Zn
* Numbers in parentheses represent concentration FDs, calculated based on average concentration obtained divided by FAO limits.
The causes for HM contamination in surface water bodies are both natural and anthropogenic. The natural causes include, among others, atmospheric deposition, geological and biological weathering, and climatic change. The anthropogenic causes include, but are not limited to, discharge of HM-contaminated agricultural, municipal, domestic, and industrial wastes. HM elements such as Pb, Ni, Cr, Cd, As, Hg, Zn, Cu, and others from diverse sources are transported to surface water bodies and irrigation canals through runoff, and to underground aquifers through vertical leaching with percolating rainwater [16,59,60,61][16][59][60][61]. Thus, irrigation of croplands using HM-contaminated water not only affects the growth and productivity of crops [62], but can also threaten soil quality. It should, however, be noted that the extent of crop damage will depend on the pH of the irrigation water, redox potential, and water solubility of the contaminated HM elements.

References

  1. Pourret, O.; Hursthouse, A. It’s Time to Replace the Term “Heavy Metals” with “Potentially Toxic Elements” When Reporting Environmental Research. Int. J. Environ. Res. Public Health 2019, 16, 4446.
  2. Maksymiec, W. Signaling responses in plants to heavy metal stress. Acta Physiol. Plant. 2007, 29, 177–187.
  3. Shahid, M.; Khalid, S.; Abbas, G.; Shahid, N.; Nadeem, M.; Sabir, M.; Aslam, M.; Dumat, C. Heavy Metal Stress and Crop Productivity. In Crop Production and Global Environmental Issues; Hakeem, H.R., Ed.; Springer International Publishing: Chem, Switzerland, 2015.
  4. Wuana, R.A.; Okieimen, F.E. Heavy Metals in Contaminated Soils: A Review of Sources, Chemistry, Risks and Best Available Strategies for Remediation. Intern. Sch. Res. Net. Ecol. 2011, 2011, 402647.
  5. Ghori, N.H.; Ghori, T.; Hayat, M.Q.; Imadi, S.R.; Gul, A.; Altay, V.; Ozturk, M. Heavy metal stress and responses in plants. Int. J. Envn. Sci. Technol. 2019, 16, 1807–1828.
  6. Ali, H.; Khan, E.; Ilahi, I. Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. J. Chem. 2019, 2019, 6730305.
  7. Tóth, G.; Hermann, T.; Da Silva, M.R.; Montanarella, C. Heavy metals in agricultural soils of the European Union with implications for food safety. Environ. Intern. 2016, 88, 299–309.
  8. Tiwari, S.; Lata, C. Heavy Metal Stress, Signaling, and Tolerance Due to Plant-Associated Microbes: An Overview; CSIR-National Botanical Research Institute: Lucknow, India, 2018.
  9. Rai, P.K.; Leeb, S.S.; Zhangc Tsangd, U.F.; Kime, K.H. Heavy metals in food crops: Health risks, fate, mechanisms, and management. Environ. Inter. 2019, 125, 365–385.
  10. Singh, S.; Parihar, P.; Singh, R.; Singh, V.P.; Prasad, S.M. Heavy Metal Tolerance in Plants: Role of Transcriptomics, Proteomics, Metabolomics, and Ionomics. Front. Plant Sci. 2016, 6, 1143.
  11. Bashir, K.; Rasheed, S.; Kobayashi, T.; Seki, M.; Nishizawa, N.K. Regulating Subcellular Metal Homeostasis: The Key to Crop Improvement. Front. Plant Sci. 2016, 7, 1192.
  12. Järup, L. Hazards of heavy metal contamination. Br. Med. Bull. 2003, 68, 167–182.
  13. Sharma, R.K.; Agrawal, M.; Marshall, F.M. Atmospheric deposition of heavy metals (Cu, Zn, Cd and Pb) in Varanasi City, India. Environ. Monit. Assess 2008, 142, 269–278.
  14. Kumar, K.; Singh, D.P.; Barman, S.C.; Kumar, N. Heavy Metal and Their Regulation in Plant System: An Overview. In Plant Responses to Xenobiotics; Singh, A., Prasad, S.M., Singh, R.P., Eds.; Chapter 2; Springer Nature Singapore Pte Ltd.: Singapore, 2016; pp. 19–38.
  15. Hasnine, M.T.; Huda, M.E.; Khatun, R.; Saadat, A.H.M.; Ahasan, M.; Akter, S.; Uddin, M.F.; Monika, A.N.; Rahman, M.A.; Ohiduzzaman, M. Heavy Metal Contamination in Agricultural Soil at DEPZA, Bangladesh. Environ. Ecol. Res. 2017, 5, 510–516.
  16. Ahmed, M.; Matsumoto, M.; Ozaki, A.; Thinh, N.V.; Kurosawa, K. Heavy metal Contamination of Irrigation Water, Soil, and Vegetables and the Difference between Dry and Wet Seasons Near a Multi-Industry Zone in Bangladesh. Water 2019, 11, 583.
  17. Arao, T.; Ishikawa, S.; Murakami, M.; Abe, K.; Maejima, Y.; Makino, T. Heavy metal contamination of agricultural soil and countermeasures in Japan. Paddy Water Environ. 2010, 8, 247–257.
  18. Gebreyesus, S.T. Heavy Metals in Contaminated Soil: Sources & Washing through Chemical Extractants. Am. Sci. Res. J. Eng. Technol. Sci. (ASRJETS) 2014, 10, 54–60.
  19. Obinnaa, I.B.; Ebere, E.C. Water pollution by heavy metal and organic pollutants: Brief review of sources, effects, and progress on remediation with aquatic plants. Anal. Meth. Environ. Chem. J. 2019, 2, 5–38.
  20. Kumar, V.; Singh, J.; Kumar, P. Heavy metals accumulation in crop plants: Sources, response mechanisms, stress tolerance and their effects. In Contaminants in Agriculture and Environment: Health Risks and Remediation; Kumar, V., Kumar, R., Singh, J., Kumar, P., Eds.; Agro Environ Media: Haridwar, India, 2019; Volume 1, pp. 38–57.
  21. Ritche, H.; Roser, M.; Rosado, P. Fertilizer Consumption, 1961 to 2019. World in Data. Source: Food and Agriculture Organization of the United Nations via the United States Department for Agriculture (USDA). 2022. Available online: https://ourworldindata.org/fertilizers (accessed on 28 March 2023).
  22. Gimeno-Garcíaa, E.; Andreua, V.; Boluda, R. Heavy metals incidence in the application of inorganic fertilizers and pesticides to rice farming soils. Environ. Pollut. 1996, 92, 19–25.
  23. Mar, S.S.; Okazaki, M.; Motobayashi, T. The influence of phosphate fertilizer application levels and cultivars on cadmium uptake by Komatsuna (Brassica rapa L. var. perviridis). Soil Sci. Plant Nutr. 2012, 58, 492–502.
  24. Wei, B.; Yu, J.; Cao, Z.; Meng, M.; Yang, L.; Chen, Q. The Availability and Accumulation of Heavy Metals in Greenhouse Soils Associated with Intensive Fertilizer Application. Int. J. Environ. Res. Public Health 2020, 17, 5359.
  25. Thomas, E.Y.; Omueti, J.A.I.; Ogundayomi, O. The Effect of Phosphate Fertilizer on Heavy Metal in soils and Amaranthus caudatus. Agric. Biol. J. N. Am. 2012, 3, 145–149.
  26. Zhuang, Z.; Mu, H.; Fu, P.; Wan, Y.; Yu, Y.; Wang, Q.; Li, H. Accumulation of potentially toxic elements in agricultural soil and scenario analysis of Cd inputs by fertilization: A case study in Quzhou county. J. Environ. Manag. 2020, 269, 110797.
  27. Satarug, S.; Baker, J.R.; Urbenjapol, S.; Haswell-Elkins, M.; Reilly, P.E.B.; Williams, D.J.; Moore, M.R. A global perspective on cadmium pollution and toxicity in non-occupationally exposed populations. Toxicol. Lett. 2003, 137, 65–83.
  28. Atafar, Z.; Mesdaghinia, A.; Nouri, J.; Homaee, M.; Yunesian, M.; Moghaddam, M.; Mahvi, A.H. Effect of fertilizer application on soil heavy metal conc. Environ. Monit. Assess. 2010, 160, 83–89.
  29. Al-Shawi, A.W.; Dahl, R. The determination of cadmium and six other heavy metals in nitrate/phosphate fertilizer solution by ion chromatography. Anal. Chim. Acta 1999, 391, 35–42.
  30. Samreen, S.; Kausar, S. Phosphorus Fertilizer: The Original and Commercial Sources. In Phosphorus; Zhang, T., Ed.; InteTechOpen: London, UK, 2019; Available online: https://www.intechopen.com/chapters/64614 (accessed on 28 March 2023).
  31. Paz, C.G.; Rodríguez, T.T.; Behan-Pelletier, V.M.; Hill, S.B.; Vidal-Torrado, P.; van Straaten, P. Fertilizer Raw Materials. In Encyclopedia of Soil Science; Chesworth, W., Ed.; Encyclopedia of Earth Sciences Series; Springer: Dordrecht, The Netherlands, 2008.
  32. Luo, L.; Maa, Y.; Zhang, S.; Wei, D.; Zhu, Y.-G. An inventory of trace element inputs to agricultural soils in China. J. Environ. Manag. 2009, 90, 2524–2530.
  33. McNalley, P. Heavy Metals in Fertilizers. Data collection: MNDA. EH: Minnesota Dept. Health. 2020. Available online: https://www.health.state.mn.us/communities/environment/risk/studies/metals.html (accessed on 28 March 2023).
  34. Oerke, W.C. Crop losses to pests. J. Agric. Sci. 2006, 144, 31–43.
  35. Tudi, M.; Ruan, H.D.; LiWang, L.L.; Sadler, R.; Connell, D.; Chu, C.; Phung, D.T. Agriculture Development, Pesticide Application and Its Impact on the Environment. Int. J. Environ. Res. Public Health 2021, 18, 1112.
  36. PPDB (Pesticides Properties Data Base). International Union of Pure and Applied Chemistry, UPAC. 2007. Available online: http://sitem.herts.ac.uk/aeru/ppdb/en/atoz.htm (accessed on 28 March 2023).
  37. Lewis, K.A.; Tzilivakis, J.; Warner, D.; Green, A. An international database for pesticide risk assessments and management. J. Hum. Ecol. Risk Assess. 2016, 22, 1050–1064.
  38. Defarge, N.; de-Vendômois, S.; Séralinia, G.E. Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides. Toxicol. Rep. 2018, 5, 156–163.
  39. Alnuwaiser, M.A. An Analytical Survey of Trace Heavy Elements in Insecticides. Intern. J. Anal. Chem. 2019, 2019, 8150793.
  40. Priyanka, P.; Kumar, D.K.; Yadav, A.; Yadav, K. Nanobiotechnology and its application in agriculture and food production. In Nanotechnology for Food, Agriculture, and Environment; Springer: Berlin/Heidelberg, Germany, 2020; pp. 105–134.
  41. Wang, H.; Dong, Y.; Yang, Y.; Toor, G.S.; Zhang, X. Changes in heavy metal contents in animal feeds and manures in an intensive animal production region of China. J. Environ. Sci. 2013, 25, 2435–2442.
  42. Liu, W.R.; Zenga, D.; She, L.; Su, W.X.; He, D.C.; Wua, G.Y.; Ma, X.R.; Jiang, S.; Jiang, C.J.; Ying, G.G. Comparisons of pollution characteristics, emission situations, and mass loads for heavy metals in the manures of different livestock and poultry in China. Sci. Total Environ. 2020, 734, 139023.
  43. NAS (National Academy of Science). Arsenic: Medical and Biologic Effects of Environmental Pollutants. 5. Biologic Effects of Arsenic on Plants and Animals; National Academies Press: Washington, DC, USA, 1977; Volume 5, pp. 1–332. Available online: https://www.ncbi.nlm.nih.gov/books/NBK231025 (accessed on 28 March 2023).
  44. Hu, Y.; Zhang, W.; Chen, G.; Cheng, H.; Tao, S. Public health risk of trace metals in fresh chicken meat products on the food markets of a major production region in southern China. Environ. Pollut. 2018, 234, 667–676.
  45. Zhang, F.; Yanxia Li Yang, M.; Wei, L. Content of Heavy Metals in Animal Feeds and Manures from Farms of Different Scales in Northeast China. Int. J. Environ. Res. Public Health 2012, 9, 2658–2668.
  46. Jensen, J.; Larsen, M.M.; Bak, J. National monitoring study in Denmark finds increased and critical levels of copper and zinc in arable soils fertilized with pig slurry. Environ. Pollut. 2016, 214, 334–340.
  47. Lopes, C.; Herva, M.; Franco-Uría, A.; Roca, E. Inventory of heavy metal content in organic waste applied as fertilizer in agriculture: Evaluating the risk of transfer into the food chain. Environ. Sci. Pollut. Res. 2011, 18, 918–939.
  48. Zhao, Y.; Yan, Z.; Qin, J. Effects of long-term cattle manure application on soil properties and soil heavy metals in corn seed production in NW China. Environ. Sci. Pol. Res. 2014, 21, 7586–7595.
  49. Yang, X.P.; Li, Q.; Tang, Z.; Zhang, W.W.; Yu, G.H.; Shen, Q.R.; Zhao, F.J. Heavy metal conc. and arsenic speciation in animal manure composts in China. Waste Manag. 2017, 64, 333–339.
  50. Zarcinas, B.A.; Ishak, C.E.; McLaughlin, M.J.; Cozens, G. Heavy metals in soils and crops in southeast Asia. 1. Peninsular Malaysia. Environ. Geochem. Health 2004, 26, 343–357.
  51. MDEQ Bulletin. What Are Biosolids, How Are They Used, and Are They Safe? Water Resources Division, Michigan Department of Environmental Quality; 2014. Available online: https://www.michigan.gov/-/media/Project/Websites/egle/Documents/Programs/WRD/Biosolids/biosolids-what-how-safe (accessed on 28 March 2023).
  52. Kissel, K.E.; Rodriguez, L.; Paz, J.; Mitchell, C.; Patrick, S.; Zhang, H.; Fielder, K.; Morris, L. Metal Concentration Standards for Land Application of Biosolids and Other By-Products in Georgia. Bulletin 2017, 1353, 1–4.
  53. Silveira, M.L.A.; Alleoni, L.R.F.; Guilherme, L.R.G. Biosolids and heavy metals in soils. Sci. Agric. 2003, 60, 64–111.
  54. McLaughlin, M.J.; Hamon, R.E.; McLaren, R.G.; Speir, T.W.; Rogers, S.L. A bioavailability-based rationale for controlling metal and metalloid contamination of agric.land in Australia and New Zealand. Aust. J. Soil Res. 2000, 38, 1037–1086.
  55. EPA (Environmental Protection Agency). A Plain English Guide to the EPA Part 503 Biosolids Rule. 2023; EPA 40 CFR Part 503. Available online: https://www.epa.gov/biosolids/plain-english-guide-epa-part-503-biosolids-rule (accessed on 28 March 2023).
  56. Hossain, M.F. Arsenic contamination in Bangladesh. Agric. Ecosys. Environ. 2006, 113, 1–16.
  57. Hussain, M.M.; Hina, A.; Saeed, A.; Sabahat, S.; Jannat, F.; Aslam, M. Impact of heavy metals on plants and animals in relation to sewage water: A Review. Sci. Technol. Dev. 2017, 36, 215–226.
  58. Berihun, B.T.; Amare, D.E.; Raju, R.P.; Ayele, D.T.; Dagne, H. Determination of the Level of Metallic Contamination in Irrigation Vegetables, the Soil, and the Water in Gondar City, Ethiopia. Nutr. Diet. Suppl. 2021, 13, 1–7.
  59. Rai, P.K.; Tripathi, B.D. Heavy metals in industrial wastewater, soil and vegetables in Lohta village, India. Toxic. Environ. Chem. 2007, 90, 247–257.
  60. Mohankumar, K.; Hariharan, V.; Rao, N.P. Heavy Metal Contamination in Groundwater around Industrial Estate vs. Residential Areas in Coimbatore, India. J. Clin. Diag. Res. 2016, 10, BC05–BC07.
  61. Huq, E.M.; Su, C.; Lia, J.; Sarven, M.S. Arsenic enrichment and mobilization in the Holocene alluvial aquifers of Prayagpur of Southwestern Bangladesh. Intern. Biod. Biodeg. 2018, 128, 186–194.
  62. Ashfaque, F.; Inam, A.; Sahay, S.; Iqbal, S. Influence of Heavy Metal Toxicity on Plant Growth, Metabolism and Its Alleviation by Phytoremediation—A Promising Technology. J. Agric. Ecol. Res. Inter. 2016, 6, 1–19.
More
© Text is available under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)
ScholarVision Creations
Feedback