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Li, V. GALC Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/5613 (accessed on 21 September 2026).
Li V. GALC Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/5613. Accessed September 21, 2026.
Li, Vivi. "GALC Gene" Encyclopedia, https://encyclopedia.pub/entry/5613 (accessed September 21, 2026).
Li, V. (2020, December 25). GALC Gene. In Encyclopedia. https://encyclopedia.pub/entry/5613
Li, Vivi. "GALC Gene." Encyclopedia. Web. 25 December, 2020.
GALC Gene
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/galc

Galactosylceramidase: The GALC gene provides instructions for making an enzyme called galactosylceramidase. 

genes

References

  1. Giri S, Khan M, Rattan R, Singh I, Singh AK. Krabbe disease:psychosine-mediated activation of phospholipase A2 in oligodendrocyte cell death.J Lipid Res. 2006 Jul;47(7):1478-92.
  2. Shin D, Feltri ML, Wrabetz L. Altered Trafficking and Processing of GALCMutants Correlates with Globoid Cell Leukodystrophy Severity. J Neurosci. 2016Feb 10;36(6):1858-70. doi: 10.1523/JNEUROSCI.3095-15.2016.
  3. Spratley SJ, Hill CH, Viuff AH, Edgar JR, Skjødt K, Deane JE. MolecularMechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants. Traffic.2016 Aug;17(8):908-22. doi: 10.1111/tra.12404.
  4. Wenger DA, Rafi MA, Luzi P. Krabbe disease: One Hundred years from the bedsideto the bench to the bedside. J Neurosci Res. 2016 Nov;94(11):982-9. doi:10.1002/jnr.23743. Review.
  5. Zaka M, Wenger DA. Psychosine-induced apoptosis in a mouse oligodendrocyteprogenitor cell line is mediated by caspase activation. Neurosci Lett. 2004 Apr1;358(3):205-9.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vivi Li
View Times: 886
Entry Collection: MedlinePlus
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Update Date: 25 Dec 2020
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