FUS Gene

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1		Vivi Li	+ 631 word(s)	631	2020-12-15 07:53:57

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Li, V. FUS Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/5603 (accessed on 21 September 2026).

Li V. FUS Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/5603. Accessed September 21, 2026.

Li, Vivi. "FUS Gene" Encyclopedia, https://encyclopedia.pub/entry/5603 (accessed September 21, 2026).

Li, V. (2020, December 25). FUS Gene. In Encyclopedia. https://encyclopedia.pub/entry/5603

Li, Vivi. "FUS Gene." Encyclopedia. Web. 25 December, 2020.

FUS Gene

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/fus

FUS RNA binding protein

genes

References

Coady TH, Manley JL. ALS mutations in TLS/FUS disrupt target gene expression. Genes Dev. 2015 Aug 15;29(16):1696-706. doi: 10.1101/gad.267286.115.
Crozat A, Aman P, Mandahl N, Ron D. Fusion of CHOP to a novel RNA-bindingprotein in human myxoid liposarcoma. Nature. 1993 Jun 17;363(6430):640-4.
Deng H, Gao K, Jankovic J. The role of FUS gene variants in neurodegenerative diseases. Nat Rev Neurol. 2014 Jun;10(6):337-48. doi: 10.1038/nrneurol.2014.78.
Hewitt C, Kirby J, Highley JR, Hartley JA, Hibberd R, Hollinger HC, WilliamsTL, Ince PG, McDermott CJ, Shaw PJ. Novel FUS/TLS mutations and pathology infamilial and sporadic amyotrophic lateral sclerosis. Arch Neurol. 2010Apr;67(4):455-61. doi: 10.1001/archneurol.2010.52.
Panagopoulos I, Storlazzi CT, Fletcher CD, Fletcher JA, Nascimento A, DomanskiHA, Wejde J, Brosjö O, Rydholm A, Isaksson M, Mandahl N, Mertens F. The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma. Genes ChromosomesCancer. 2004 Jul;40(3):218-28.
Schwartz JC, Podell ER, Han SS, Berry JD, Eggan KC, Cech TR. FUS issequestered in nuclear aggregates in ALS patient fibroblasts. Mol Biol Cell. 2014Sep 1;25(17):2571-8. doi: 10.1091/mbc.E14-05-1007.
Storlazzi CT, Mertens F, Nascimento A, Isaksson M, Wejde J, Brosjo O, Mandahl N, Panagopoulos I. Fusion of the FUS and BBF2H7 genes in low grade fibromyxoidsarcoma. Hum Mol Genet. 2003 Sep 15;12(18):2349-58.
Vance C, Rogelj B, Hortobágyi T, De Vos KJ, Nishimura AL, Sreedharan J, Hu X, Smith B, Ruddy D, Wright P, Ganesalingam J, Williams KL, Tripathi V, Al-Saraj S, Al-Chalabi A, Leigh PN, Blair IP, Nicholson G, de Belleroche J, Gallo JM, Miller CC, Shaw CE. Mutations in FUS, an RNA processing protein, cause familialamyotrophic lateral sclerosis type 6. Science. 2009 Feb 27;323(5918):1208-1211.doi: 10.1126/science.1165942.
Wang X, Arai S, Song X, Reichart D, Du K, Pascual G, Tempst P, Rosenfeld MG,Glass CK, Kurokawa R. Induced ncRNAs allosterically modify RNA-binding proteinsin cis to inhibit transcription. Nature. 2008 Jul 3;454(7200):126-30. doi:10.1038/nature06992.

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Subjects: Genetics & Heredity

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Entry Collection: MedlinePlus

Update Date: 25 Dec 2020

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