ATRX Gene

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1		Vicky Zhou	+ 471 word(s)	471	2020-12-15 07:45:31

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Zhou, V. ATRX Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4922 (accessed on 28 September 2026).

Zhou V. ATRX Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4922. Accessed September 28, 2026.

Zhou, Vicky. "ATRX Gene" Encyclopedia, https://encyclopedia.pub/entry/4922 (accessed September 28, 2026).

Zhou, V. (2020, December 24). ATRX Gene. In Encyclopedia. https://encyclopedia.pub/entry/4922

Zhou, Vicky. "ATRX Gene." Encyclopedia. Web. 24 December, 2020.

ATRX Gene

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/atrx

ATRX, chromatin remodeler

genes

References

Argentaro A, Yang JC, Chapman L, Kowalczyk MS, Gibbons RJ, Higgs DR, NeuhausD, Rhodes D. Structural consequences of disease-causing mutations in theATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX. ProcNatl Acad Sci U S A. 2007 Jul 17;104(29):11939-44.
Badens C, Lacoste C, Philip N, Martini N, Courrier S, Giuliano F, Verloes A,Munnich A, Leheup B, Burglen L, Odent S, Van Esch H, Levy N. Mutations inPHD-like domain of the ATRX gene correlate with severe psychomotor impairment andsevere urogenital abnormalities in patients with ATRX syndrome. Clin Genet. 2006 Jul;70(1):57-62.
Gibbons R. Alpha thalassaemia-mental retardation, X linked. Orphanet J RareDis. 2006 May 4;1:15. Review.
Gibbons RJ, Pellagatti A, Garrick D, Wood WG, Malik N, Ayyub H, Langford C,Boultwood J, Wainscoat JS, Higgs DR. Identification of acquired somatic mutationsin the gene encoding chromatin-remodeling factor ATRX in the alpha-thalassemiamyelodysplasia syndrome (ATMDS). Nat Genet. 2003 Aug;34(4):446-9.
Gibbons RJ, Wada T, Fisher CA, Malik N, Mitson MJ, Steensma DP, Fryer A,Goudie DR, Krantz ID, Traeger-Synodinos J. Mutations in the chromatin-associated protein ATRX. Hum Mutat. 2008 Jun;29(6):796-802. doi: 10.1002/humu.20734.
Steensma DP, Gibbons RJ, Higgs DR. Acquired alpha-thalassemia in associationwith myelodysplastic syndrome and other hematologic malignancies. Blood. 2005 Jan15;105(2):443-52.
Steensma DP, Higgs DR, Fisher CA, Gibbons RJ. Acquired somatic ATRX mutations in myelodysplastic syndrome associated with alpha thalassemia (ATMDS) convey amore severe hematologic phenotype than germline ATRX mutations. Blood. 2004 Mar15;103(6):2019-26.
Xue Y, Gibbons R, Yan Z, Yang D, McDowell TL, Sechi S, Qin J, Zhou S, Higgs D,Wang W. The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies. Proc Natl Acad Sci U S A.2003 Sep 16;100(19):10635-40.

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Subjects: Genetics & Heredity

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Update Date: 24 Dec 2020

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