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Zhou, V. APP Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4716 (accessed on 26 September 2026).
Zhou V. APP Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4716. Accessed September 26, 2026.
Zhou, Vicky. "APP Gene" Encyclopedia, https://encyclopedia.pub/entry/4716 (accessed September 26, 2026).
Zhou, V. (2020, December 24). APP Gene. In Encyclopedia. https://encyclopedia.pub/entry/4716
Zhou, Vicky. "APP Gene." Encyclopedia. Web. 24 December, 2020.
APP Gene
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/app

amyloid beta precursor protein

genes

References

  1. Bornebroek M, De Jonghe C, Haan J, Kumar-Singh S, Younkin S, Roos R, VanBroeckhoven C. Hereditary cerebral hemorrhage with amyloidosis Dutch type(AbetaPP 693): decreased plasma amyloid-beta 42 concentration. Neurobiol Dis.2003 Dec;14(3):619-23.
  2. Caillé I, Allinquant B, Dupont E, Bouillot C, Langer A, Müller U, ProchiantzA. Soluble form of amyloid precursor protein regulates proliferation ofprogenitors in the adult subventricular zone. Development. 2004May;131(9):2173-81.
  3. Conti L, Cattaneo E. Controlling neural stem cell division within the adultsubventricular zone: an APPealing job. Trends Neurosci. 2005 Feb;28(2):57-9.Review.
  4. Cordy JM, Hooper NM, Turner AJ. The involvement of lipid rafts in Alzheimer's disease. Mol Membr Biol. 2006 Jan-Feb;23(1):111-22. Review.
  5. Edwards-Lee T, Ringman JM, Chung J, Werner J, Morgan A, St George Hyslop P,Thompson P, Dutton R, Mlikotic A, Rogaeva E, Hardy J. An African American family with early-onset Alzheimer disease and an APP (T714I) mutation. Neurology. 2005Jan 25;64(2):377-9.
  6. Fernandez-Madrid I, Levy E, Marder K, Frangione B. Codon 618 variant ofAlzheimer amyloid gene associated with inherited cerebral hemorrhage. Ann Neurol.1991 Nov;30(5):730-3.
  7. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progressand problems on the road to therapeutics. Science. 2002 Jul 19;297(5580):353-6.Review. Erratum in: Science 2002 Sep 27;297(5590):2209.
  8. Harman D. Alzheimer's disease pathogenesis: role of aging. Ann N Y Acad Sci.2006 May;1067:454-60. Review.
  9. Kerr ML, Small DH. Cytoplasmic domain of the beta-amyloid protein precursor ofAlzheimer's disease: function, regulation of proteolysis, and implications fordrug development. J Neurosci Res. 2005 Apr 15;80(2):151-9. Review.
  10. Levy E, Prelli F, Frangione B. Studies on the first described Alzheimer'sdisease amyloid beta mutant, the Dutch variant. J Alzheimers Dis. 2006;9(3Suppl):329-39. Review.
  11. Maat-Schieman M, Roos R, van Duinen S. Hereditary cerebral hemorrhage withamyloidosis-Dutch type. Neuropathology. 2005 Dec;25(4):288-97. Review.
  12. Majersik JJ, Skalabrin EJ. Single-gene stroke disorders. Semin Neurol. 2006Feb;26(1):33-48. Review.
  13. Obici L, Demarchi A, de Rosa G, Bellotti V, Marciano S, Donadei S, ArbustiniE, Palladini G, Diegoli M, Genovese E, Ferrari G, Coverlizza S, Merlini G. Anovel AbetaPP mutation exclusively associated with cerebral amyloid angiopathy.Ann Neurol. 2005 Oct;58(4):639-44.
  14. Papassotiropoulos A, Fountoulakis M, Dunckley T, Stephan DA, Reiman EM.Genetics, transcriptomics, and proteomics of Alzheimer's disease. J ClinPsychiatry. 2006 Apr;67(4):652-70. Review.
  15. Rocchi A, Pellegrini S, Siciliano G, Murri L. Causative and susceptibilitygenes for Alzheimer's disease: a review. Brain Res Bull. 2003 Jun 30;61(1):1-24. Review.
  16. Salameh MA, Robinson JL, Navaneetham D, Sinha D, Madden BJ, Walsh PN, Radisky ES. The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is ahighly specific substrate of mesotrypsin. J Biol Chem. 2010 Jan15;285(3):1939-49. doi: 10.1074/jbc.M109.057216.
  17. Wolfe MS, Guénette SY. APP at a glance. J Cell Sci. 2007 Sep 15;120(Pt18):3157-61. Review.
  18. Zhang H, Ma Q, Zhang YW, Xu H. Proteolytic processing of Alzheimer's β-amyloidprecursor protein. J Neurochem. 2012 Jan;120 Suppl 1:9-21. doi:10.1111/j.1471-4159.2011.07519.x.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vicky Zhou
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Entry Collection: MedlinePlus
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Update Date: 24 Dec 2020
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