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Li, V. DARS2 Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4532 (accessed on 28 September 2026).
Li V. DARS2 Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4532. Accessed September 28, 2026.
Li, Vivi. "DARS2 Gene" Encyclopedia, https://encyclopedia.pub/entry/4532 (accessed September 28, 2026).
Li, V. (2020, December 23). DARS2 Gene. In Encyclopedia. https://encyclopedia.pub/entry/4532
Li, Vivi. "DARS2 Gene." Encyclopedia. Web. 23 December, 2020.
DARS2 Gene
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/dars2

Aspartyl-tRNA Synthetase 2, Mitochondrial: The DARS2 gene provides instructions for making an enzyme called mitochondrial aspartyl-tRNA synthetase. 

genes

References

  1. Lin J, Chiconelli Faria E, Da Rocha AJ, Rodrigues Masruha M, Pereira Vilanova LC, Scheper GC, Van der Knaap MS. Leukoencephalopathy with brainstem and spinalcord involvement and normal lactate: a new mutation in the DARS2 gene. J ChildNeurol. 2010 Nov;25(11):1425-8. doi: 10.1177/0883073810370897.
  2. Scheper GC, van der Klok T, van Andel RJ, van Berkel CG, Sissler M, Smet J,Muravina TI, Serkov SV, Uziel G, Bugiani M, Schiffmann R, Krägeloh-Mann I,Smeitink JA, Florentz C, Van Coster R, Pronk JC, van der Knaap MS. Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stemand spinal cord involvement and lactate elevation. Nat Genet. 2007Apr;39(4):534-9.
  3. Uluc K, Baskan O, Yildirim KA, Ozsahin S, Koseoglu M, Isak B, Scheper GC,Gunal DI, van der Knaap MS. Leukoencephalopathy with brain stem and spinal cordinvolvement and high lactate: a genetically proven case with distinct MRIfindings. J Neurol Sci. 2008 Oct 15;273(1-2):118-22. doi:10.1016/j.jns.2008.06.002.
  4. van der Knaap MS, van der Voorn P, Barkhof F, Van Coster R, Krägeloh-Mann I,Feigenbaum A, Blaser S, Vles JS, Rieckmann P, Pouwels PJ. A newleukoencephalopathy with brainstem and spinal cord involvement and high lactate. Ann Neurol. 2003 Feb;53(2):252-8.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vivi Li
View Times: 747
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 23 Dec 2020
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