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Li, V. DARS1 Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4531 (accessed on 29 September 2026).
Li V. DARS1 Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4531. Accessed September 29, 2026.
Li, Vivi. "DARS1 Gene" Encyclopedia, https://encyclopedia.pub/entry/4531 (accessed September 29, 2026).
Li, V. (2020, December 23). DARS1 Gene. In Encyclopedia. https://encyclopedia.pub/entry/4531
Li, Vivi. "DARS1 Gene." Encyclopedia. Web. 23 December, 2020.
DARS1 Gene
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/dars1

Aspartyl-tRNA Synthetase: The DARS1 gene provides instructions for making an enzyme called aspartyl-tRNA synthetase. 

genes

References

  1. Fröhlich D, Suchowerska AK, Voss C, He R, Wolvetang E, von Jonquieres G,Simons C, Fath T, Housley GD, Klugmann M. Expression Pattern of the Aspartyl-tRNASynthetase DARS in the Human Brain. Front Mol Neurosci. 2018 Mar 20;11:81. doi:10.3389/fnmol.2018.00081.
  2. Park SG, Choi EC, Kim S. Aminoacyl-tRNA synthetase-interacting multifunctionalproteins (AIMPs): a triad for cellular homeostasis. IUBMB Life. 2010Apr;62(4):296-302. doi: 10.1002/iub.324. Review.
  3. Taft RJ, Vanderver A, Leventer RJ, Damiani SA, Simons C, Grimmond SM, MillerD, Schmidt J, Lockhart PJ, Pope K, Ru K, Crawford J, Rosser T, de Coo IF, Juneja M, Verma IC, Prabhakar P, Blaser S, Raiman J, Pouwels PJ, Bevova MR, Abbink TE,van der Knaap MS, Wolf NI. Mutations in DARS cause hypomyelination with brainstem and spinal cord involvement and leg spasticity. Am J Hum Genet. 2013 May2;92(5):774-80. doi: 10.1016/j.ajhg.2013.04.006.
  4. Wolf NI, Toro C, Kister I, Latif KA, Leventer R, Pizzino A, Simons C, AbbinkTE, Taft RJ, van der Knaap MS, Vanderver A. DARS-associated leukoencephalopathycan mimic a steroid-responsive neuroinflammatory disorder. Neurology. 2015 Jan20;84(3):226-30. doi: 10.1212/WNL.0000000000001157.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vivi Li
View Times: 707
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 23 Dec 2020
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