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Xu, R. Neuromyelitis Optica. Encyclopedia. Available online: https://encyclopedia.pub/entry/4517 (accessed on 29 September 2026).
Xu R. Neuromyelitis Optica. Encyclopedia. Available at: https://encyclopedia.pub/entry/4517. Accessed September 29, 2026.
Xu, Rita. "Neuromyelitis Optica" Encyclopedia, https://encyclopedia.pub/entry/4517 (accessed September 29, 2026).
Xu, R. (2020, December 23). Neuromyelitis Optica. In Encyclopedia. https://encyclopedia.pub/entry/4517
Xu, Rita. "Neuromyelitis Optica." Encyclopedia. Web. 23 December, 2020.
Neuromyelitis Optica
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/neuromyelitis-optica

Neuromyelitis optica is an autoimmune disorder that affects the nerves of the eyes and the central nervous system, which includes the brain and spinal cord. Autoimmune disorders occur when the immune system malfunctions and attacks the body's own tissues and organs. In neuromyelitis optica, the autoimmune attack causes inflammation of the nerves, and the resulting damage leads to the signs and symptoms of the condition.

genetic conditions

References

  1. Hinson SR, Pittock SJ, Lucchinetti CF, Roemer SF, Fryer JP, Kryzer TJ, Lennon VA. Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica. Neurology. 2007 Dec 11;69(24):2221-31.
  2. Matiello M, Kim HJ, Kim W, Brum DG, Barreira AA, Kingsbury DJ, Plant GT, AdoniT, Weinshenker BG. Familial neuromyelitis optica. Neurology. 2010 Jul27;75(4):310-5. doi: 10.1212/WNL.0b013e3181ea9f15.
  3. Matiello M, Schaefer-Klein JL, Hebrink DD, Kingsbury DJ, Atkinson EJ,Weinshenker BG; NMO Genetics Collaborators. Genetic analysis of aquaporin-4 inneuromyelitis optica. Neurology. 2011 Sep 20;77(12):1149-55. doi:10.1212/WNL.0b013e31822f045b.
  4. Matà S, Lolli F. Neuromyelitis optica: an update. J Neurol Sci. 2011 Apr15;303(1-2):13-21. doi: 10.1016/j.jns.2011.01.002. Review.
  5. National Institute of Neurological Disorders and Stroke: Neuromyelitis Optica Information Page
  6. Sato DK, Lana-Peixoto MA, Fujihara K, de Seze J. Clinical spectrum andtreatment of neuromyelitis optica spectrum disorders: evolution and currentstatus. Brain Pathol. 2013 Nov;23(6):647-60. doi: 10.1111/bpa.12087. Review.
  7. Takahashi T, Fujihara K, Nakashima I, Misu T, Miyazawa I, Nakamura M, WatanabeS, Shiga Y, Kanaoka C, Fujimori J, Sato S, Itoyama Y. Anti-aquaporin-4 antibodyis involved in the pathogenesis of NMO: a study on antibody titre. Brain. 2007May;130(Pt 5):1235-43.
  8. Veszeli N, Füst G, Csuka D, Trauninger A, Bors L, Rozsa C, Nagy Z, Jobbágy Z, Eizler K, Prohászka Z, Varga L, Illes Z. A systematic analysis of the complement pathways in patients with neuromyelitis optica indicates alteration but noactivation during remission. Mol Immunol. 2014 Feb;57(2):200-9. doi:10.1016/j.molimm.2013.09.010.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Rita Xu
View Times: 734
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 23 Dec 2020
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