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Li, V. CYP11B2 Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4385 (accessed on 28 September 2026).
Li V. CYP11B2 Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4385. Accessed September 28, 2026.
Li, Vivi. "CYP11B2 Gene" Encyclopedia, https://encyclopedia.pub/entry/4385 (accessed September 28, 2026).
Li, V. (2020, December 23). CYP11B2 Gene. In Encyclopedia. https://encyclopedia.pub/entry/4385
Li, Vivi. "CYP11B2 Gene." Encyclopedia. Web. 23 December, 2020.
CYP11B2 Gene
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/cyp11b2

Cytochrome P450 Family 11 Subfamily B Member 2: The CYP11B2 gene provides instructions for making an enzyme called aldosterone synthase (previously known as corticosterone methyloxidase). 

genes

References

  1. Amir O, Amir RE, Paz H, Mor R, Sagiv M, Lewis BS. Aldosterone synthase genepolymorphism as a determinant of atrial fibrillation in patients with heartfailure. Am J Cardiol. 2008 Aug 1;102(3):326-9. doi:10.1016/j.amjcard.2008.03.063.
  2. Connell JM, Fraser R, MacKenzie SM, Friel EC, Ingram MC, Holloway CD, DaviesE. The impact of polymorphisms in the gene encoding aldosterone synthase(CYP11B2) on steroid synthesis and blood pressure regulation. Mol CellEndocrinol. 2004 Mar 31;217(1-2):243-7. Review.
  3. Martinez-Aguayo A, Fardella C. Genetics of hypertensive syndrome. Horm Res.2009;71(5):253-9. doi: 10.1159/000208798.
  4. Moraitis AG, Rainey WE, Auchus RJ. Gene mutations that promote adrenalaldosterone production, sodium retention, and hypertension. Appl Clin Genet. 2013Dec 24;7:1-13. doi: 10.2147/TACG.S35571. Review.
  5. Nguyen HH, Hannemann F, Hartmann MF, Malunowicz EM, Wudy SA, Bernhardt R. Fivenovel mutations in CYP11B2 gene detected in patients with aldosterone synthasedeficiency type I: Functional characterization and structural analyses. Mol GenetMetab. 2010 Aug;100(4):357-64. doi: 10.1016/j.ymgme.2010.04.016.
  6. Quack I, Vonend O, Rump LC. Familial hyperaldosteronism I-III. Horm Metab Res.2010 Jun;42(6):424-8. doi: 10.1055/s-0029-1246187.
  7. Stowasser M, Gordon RD. Familial hyperaldosteronism. J Steroid Biochem MolBiol. 2001 Sep;78(3):215-29. Review.
  8. White PC. Aldosterone synthase deficiency and related disorders. Mol CellEndocrinol. 2004 Mar 31;217(1-2):81-7. Review.
  9. Williams SS. Advances in genetic hypertension. Curr Opin Pediatr. 2007Apr;19(2):192-8. Review.
  10. Yu Y. The CYP11B2 -344C/T variant is associated with ischemic stroke risk: An updated meta-analysis. J Renin Angiotensin Aldosterone Syst. 2015Jun;16(2):382-8. doi: 10.1177/1470320313492362.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vivi Li
View Times: 765
Entry Collection: MedlinePlus
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Update Date: 23 Dec 2020
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