Abdominal Wall Defect

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Yang, C. Abdominal Wall Defect. Encyclopedia. Available online: https://encyclopedia.pub/entry/4363 (accessed on 29 September 2026).

Yang C. Abdominal Wall Defect. Encyclopedia. Available at: https://encyclopedia.pub/entry/4363. Accessed September 29, 2026.

Yang, Catherine. "Abdominal Wall Defect" Encyclopedia, https://encyclopedia.pub/entry/4363 (accessed September 29, 2026).

Yang, C. (2020, December 23). Abdominal Wall Defect. In Encyclopedia. https://encyclopedia.pub/entry/4363

Yang, Catherine. "Abdominal Wall Defect." Encyclopedia. Web. 23 December, 2020.

Abdominal Wall Defect

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/abdominal-wall-defect

An abdominal wall defect is an opening in the abdomen through which various abdominal organs can protrude. This opening varies in size and can usually be diagnosed early in fetal development, typically between the tenth and fourteenth weeks of pregnancy. There are two main types of abdominal wall defects: omphalocele and gastroschisis. Omphalocele is an opening in the center of the abdominal wall where the umbilical cord meets the abdomen. Organs (typically the intestines, stomach, and liver) protrude through the opening into the umbilical cord and are covered by the same protective membrane that covers the umbilical cord. Gastroschisis is a defect in the abdominal wall, usually to the right of the umbilical cord, through which the large and small intestines protrude (although other organs may sometimes bulge out). There is no membrane covering the exposed organs in gastroschisis.

genetic conditions

References

Christison-Lagay ER, Kelleher CM, Langer JC. Neonatal abdominal wall defects. Semin Fetal Neonatal Med. 2011 Jun;16(3):164-72. doi: 10.1016/j.siny.2011.02.003.
Fratelli N, Papageorghiou AT, Bhide A, Sharma A, Okoye B, Thilaganathan B.Outcome of antenatally diagnosed abdominal wall defects. Ultrasound ObstetGynecol. 2007 Sep;30(3):266-70.
Hidaka N, Murata M, Yumoto Y, Hojo S, Fujita Y, Masumoto K, Taguchi T,Tsukimori K, Wake N. Characteristics and perinatal course of prenatally diagnosedfetal abdominal wall defects managed in a tertiary center in Japan. J ObstetGynaecol Res. 2009 Feb;35(1):40-7. doi: 10.1111/j.1447-0756.2008.00871.x.
Hwang PJ, Kousseff BG. Omphalocele and gastroschisis: an 18-year review study.Genet Med. 2004 Jul-Aug;6(4):232-6.
Islam S. Clinical care outcomes in abdominal wall defects. Curr Opin Pediatr. 2008 Jun;20(3):305-10. doi: 10.1097/MOP.0b013e3282ffdc1e. Review.
Ledbetter DJ. Gastroschisis and omphalocele. Surg Clin North Am. 2006Apr;86(2):249-60, vii. Review.
Mann S, Blinman TA, Douglas Wilson R. Prenatal and postnatal management ofomphalocele. Prenat Diagn. 2008 Jul;28(7):626-32. doi: 10.1002/pd.2008. Review.
Sadler TW. The embryologic origin of ventral body wall defects. Semin Pediatr Surg. 2010 Aug;19(3):209-14. doi: 10.1053/j.sempedsurg.2010.03.006. Review.
Wilson RD, Johnson MP. Congenital abdominal wall defects: an update. FetalDiagn Ther. 2004 Sep-Oct;19(5):385-98. Review.

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Subjects: Genetics & Heredity

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Update Date: 04 Feb 2021

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