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Li, V. CXCR4 Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4344 (accessed on 27 September 2026).
Li V. CXCR4 Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4344. Accessed September 27, 2026.
Li, Vivi. "CXCR4 Gene" Encyclopedia, https://encyclopedia.pub/entry/4344 (accessed September 27, 2026).
Li, V. (2020, December 23). CXCR4 Gene. In Encyclopedia. https://encyclopedia.pub/entry/4344
Li, Vivi. "CXCR4 Gene." Encyclopedia. Web. 23 December, 2020.
CXCR4 Gene
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/cxcr4

C-X-C Motif Chemokine Receptor 4

genes

References

  1. Cao Y, Hunter ZR, Liu X, Xu L, Yang G, Chen J, Patterson CJ, Tsakmaklis N,Kanan S, Rodig S, Castillo JJ, Treon SP. The WHIM-like CXCR4(S338X) somaticmutation activates AKT and ERK, and promotes resistance to ibrutinib and otheragents used in the treatment of Waldenstrom's Macroglobulinemia. Leukemia. 2015Jan;29(1):169-76. doi: 10.1038/leu.2014.187.
  2. Cao Y, Hunter ZR, Liu X, Xu L, Yang G, Chen J, Tsakmaklis N, Kanan S, CastilloJJ, Treon SP. CXCR4 WHIM-like frameshift and nonsense mutations promote ibrutinibresistance but do not supplant MYD88(L265P) -directed survival signalling inWaldenström macroglobulinaemia cells. Br J Haematol. 2015 Mar;168(5):701-7. doi: 10.1111/bjh.13200.
  3. Dotta L, Tassone L, Badolato R. Clinical and genetic features of Warts,Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) syndrome. Curr MolMed. 2011 Jun;11(4):317-25. Review.
  4. Kawai T, Choi U, Whiting-Theobald NL, Linton GF, Brenner S, Sechler JM, MurphyPM, Malech HL. Enhanced function with decreased internalization ofcarboxy-terminus truncated CXCR4 responsible for WHIM syndrome. Exp Hematol. 2005Apr;33(4):460-8.
  5. Suratt BT, Petty JM, Young SK, Malcolm KC, Lieber JG, Nick JA, Gonzalo JA,Henson PM, Worthen GS. Role of the CXCR4/SDF-1 chemokine axis in circulatingneutrophil homeostasis. Blood. 2004 Jul 15;104(2):565-71.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vivi Li
View Times: 897
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 23 Dec 2020
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