Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 Camila Xu + 372 word(s) 372 2020-12-15 07:28:29

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
No, upload directly Yes
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Xu, C. Juvenile Paget Disease. Encyclopedia. Available online: https://encyclopedia.pub/entry/4182 (accessed on 28 September 2026).
Xu C. Juvenile Paget Disease. Encyclopedia. Available at: https://encyclopedia.pub/entry/4182. Accessed September 28, 2026.
Xu, Camila. "Juvenile Paget Disease" Encyclopedia, https://encyclopedia.pub/entry/4182 (accessed September 28, 2026).
Xu, C. (2020, December 23). Juvenile Paget Disease. In Encyclopedia. https://encyclopedia.pub/entry/4182
Xu, Camila. "Juvenile Paget Disease." Encyclopedia. Web. 23 December, 2020.
Juvenile Paget Disease
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/juvenile-paget-disease

Juvenile Paget disease is a disorder that affects bone growth. This disease causes bones to be abnormally large, misshapen, and easily broken (fractured).

genetic conditions

References

  1. Chong B, Hegde M, Fawkner M, Simonet S, Cassinelli H, Coker M, Kanis J, SeidelJ, Tau C, Tüysüz B, Yüksel B, Love D; International HyperphosphatasiaCollaborative Group. Idiopathic hyperphosphatasia and TNFRSF11B mutations:relationships between phenotype and genotype. J Bone Miner Res. 2003Dec;18(12):2095-104.
  2. Cundy T, Hegde M, Naot D, Chong B, King A, Wallace R, Mulley J, Love DR,Seidel J, Fawkner M, Banovic T, Callon KE, Grey AB, Reid IR, Middleton-Hardie CA,Cornish J. A mutation in the gene TNFRSF11B encoding osteoprotegerin causes anidiopathic hyperphosphatasia phenotype. Hum Mol Genet. 2002 Sep 1;11(18):2119-27.
  3. Cundy T. Idiopathic hyperphosphatasia. Semin Musculoskelet Radiol. 2002Dec;6(4):307-12. Review.
  4. Daroszewska A, Ralston SH. Mechanisms of disease: genetics of Paget's disease of bone and related disorders. Nat Clin Pract Rheumatol. 2006 May;2(5):270-7.Review.
  5. Janssens K, de Vernejoul MC, de Freitas F, Vanhoenacker F, Van Hul W. Anintermediate form of juvenile Paget's disease caused by a truncating TNFRSF11Bmutation. Bone. 2005 Mar;36(3):542-8.
  6. Lucas GJ, Daroszewska A, Ralston SH. Contribution of genetic factors to thepathogenesis of Paget's disease of bone and related disorders. J Bone Miner Res. 2006 Dec;21 Suppl 2:P31-7. Review.
  7. Ralston SH. Juvenile Paget's disease, familial expansile osteolysis and other genetic osteolytic disorders. Best Pract Res Clin Rheumatol. 2008Mar;22(1):101-11. doi: 10.1016/j.berh.2007.11.005. Review.
  8. Whyte MP, Obrecht SE, Finnegan PM, Jones JL, Podgornik MN, McAlister WH, Mumm S. Osteoprotegerin deficiency and juvenile Paget's disease. N Engl J Med. 2002Jul 18;347(3):175-84.
More
©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.
Upload a video for this entry
Information
Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Camila Xu
View Times: 780
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 23 Dec 2020
Table of Contents
    Notice
    You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
    OK
    Confirm
    Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
    Yes
    No
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    There is no comment~
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    ${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
    Submit
    Cancel
    Confirm
    Are you sure to Delete?
    Yes No
    Academic Video Service
    Feedback