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Xu, C. Gout. Encyclopedia. Available online: https://encyclopedia.pub/entry/4051 (accessed on 26 September 2026).
Xu C. Gout. Encyclopedia. Available at: https://encyclopedia.pub/entry/4051. Accessed September 26, 2026.
Xu, Camila. "Gout" Encyclopedia, https://encyclopedia.pub/entry/4051 (accessed September 26, 2026).
Xu, C. (2020, December 23). Gout. In Encyclopedia. https://encyclopedia.pub/entry/4051
Xu, Camila. "Gout." Encyclopedia. Web. 23 December, 2020.
Gout
Edit

Gout is a type of arthritis, which is a group of related disorders caused by episodes of abnormal inflammation in the joints. People with gout have high levels of a substance called urate in the blood (hyperuricemia).

genetic conditions

References

  1. Dalbeth N, Merriman TR, Stamp LK. Gout. Lancet. 2016 Oct22;388(10055):2039-2052. doi: 10.1016/S0140-6736(16)00346-9.Review.
  2. Dalbeth N, Stamp LK, Merriman TR. The genetics of gout: towards personalisedmedicine? BMC Med. 2017 May 31;15(1):108. doi: 10.1186/s12916-017-0878-5. Review.
  3. Ichida K, Matsuo H, Takada T, Nakayama A, Murakami K, Shimizu T, Yamanashi Y, Kasuga H, Nakashima H, Nakamura T, Takada Y, Kawamura Y, Inoue H, Okada C, UtsumiY, Ikebuchi Y, Ito K, Nakamura M, Shinohara Y, Hosoyamada M, Sakurai Y, ShinomiyaN, Hosoya T, Suzuki H. Decreased extra-renal urate excretion is a common cause ofhyperuricemia. Nat Commun. 2012 Apr 3;3:764. doi: 10.1038/ncomms1756.
  4. Khanna D, Fitzgerald JD, Khanna PP, Bae S, Singh MK, Neogi T, Pillinger MH,Merill J, Lee S, Prakash S, Kaldas M, Gogia M, Perez-Ruiz F, Taylor W, Lioté F,Choi H, Singh JA, Dalbeth N, Kaplan S, Niyyar V, Jones D, Yarows SA, Roessler B, Kerr G, King C, Levy G, Furst DE, Edwards NL, Mandell B, Schumacher HR, RobbinsM, Wenger N, Terkeltaub R; American College of Rheumatology. 2012 AmericanCollege of Rheumatology guidelines for management of gout. Part 1: systematicnonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia.Arthritis Care Res (Hoboken). 2012 Oct;64(10):1431-46. doi: 10.1002/acr.21772.
  5. Khanna D, Khanna PP, Fitzgerald JD, Singh MK, Bae S, Neogi T, Pillinger MH,Merill J, Lee S, Prakash S, Kaldas M, Gogia M, Perez-Ruiz F, Taylor W, Lioté F,Choi H, Singh JA, Dalbeth N, Kaplan S, Niyyar V, Jones D, Yarows SA, Roessler B, Kerr G, King C, Levy G, Furst DE, Edwards NL, Mandell B, Schumacher HR, RobbinsM, Wenger N, Terkeltaub R; American College of Rheumatology. 2012 AmericanCollege of Rheumatology guidelines for management of gout. Part 2: therapy andantiinflammatory prophylaxis of acute gouty arthritis. Arthritis Care Res(Hoboken). 2012 Oct;64(10):1447-61. doi: 10.1002/acr.21773.
  6. Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, PistisG, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, LiG, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, LiuX, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM,Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, TenesaA, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A,Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA,Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR,Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M,Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, UliviS, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT,Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, HollidayEG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R,Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G,Gow AJ, Bruinenberg M; LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W,Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, PlengeRM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A,Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, FarringtonSM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, ShinSY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, NelsonCP; CARDIoGRAM Consortium; DIAGRAM Consortium; ICBP Consortium; MAGIC Consortium,Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M,Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S,Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, FornageM, Gasparini P, Siscovick DS, Polašek O, Campbell H, Rudan I, Bouatia-Naji N,Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ,Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U,Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M,Fox CS, Caulfield M, Bochud M, Gieger C. Genome-wide association analysesidentify 18 new loci associated with serum urate concentrations. Nat Genet. 2013 Feb;45(2):145-54. doi: 10.1038/ng.2500.
  7. Merriman T. Genomic Influences on Hyperuricemia and Gout. Rheum Dis Clin NorthAm. 2017 Aug;43(3):389-399. doi: 10.1016/j.rdc.2017.04.004. Review.
  8. Newberry SJ, FitzGerald JD, Motala A, Booth M, Maglione MA, Han D, Tariq A,O'Hanlon CE, Shanman R, Dudley W, Shekelle PG. Diagnosis of Gout: A SystematicReview in Support of an American College of Physicians Clinical PracticeGuideline. Ann Intern Med. 2017 Jan 3;166(1):27-36. doi: 10.7326/M16-0462.
  9. Richette P, Doherty M, Pascual E, Barskova V, Becce F, Castañeda-Sanabria J,Coyfish M, Guillo S, Jansen TL, Janssens H, Lioté F, Mallen C, Nuki G, Perez-RuizF, Pimentao J, Punzi L, Pywell T, So A, Tausche AK, Uhlig T, Zavada J, Zhang W,Tubach F, Bardin T. 2016 updated EULAR evidence-based recommendations for themanagement of gout. Ann Rheum Dis. 2017 Jan;76(1):29-42. doi:10.1136/annrheumdis-2016-209707.
  10. Shekelle PG, Newberry SJ, FitzGerald JD, Motala A, O'Hanlon CE, Tariq A,Okunogbe A, Han D, Shanman R. Management of Gout: A Systematic Review in Support of an American College of Physicians Clinical Practice Guideline. Ann Intern Med.2017 Jan 3;166(1):37-51. doi: 10.7326/M16-0461.
  11. Wei WH, Guo Y, Kindt AS, Merriman TR, Semple CA, Wang K, Haley CS. Abundantlocal interactions in the 4p16.1 region suggest functional mechanisms underlying SLC2A9 associations with human serum uric acid. Hum Mol Genet. 2014 Oct1;23(19):5061-8. doi: 10.1093/hmg/ddu227.
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Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Camila Xu
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Update Date: 23 Dec 2020
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