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Xu, C. Glanzmann Thrombasthenia. Encyclopedia. Available online: https://encyclopedia.pub/entry/4008 (accessed on 29 September 2026).
Xu C. Glanzmann Thrombasthenia. Encyclopedia. Available at: https://encyclopedia.pub/entry/4008. Accessed September 29, 2026.
Xu, Camila. "Glanzmann Thrombasthenia" Encyclopedia, https://encyclopedia.pub/entry/4008 (accessed September 29, 2026).
Xu, C. (2020, December 23). Glanzmann Thrombasthenia. In Encyclopedia. https://encyclopedia.pub/entry/4008
Xu, Camila. "Glanzmann Thrombasthenia." Encyclopedia. Web. 23 December, 2020.
Glanzmann Thrombasthenia
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/glanzmann-thrombasthenia

Glanzmann thrombasthenia is a bleeding disorder that is characterized by prolonged or spontaneous bleeding starting from birth.

genetic conditions

References

  1. Nurden AT, Fiore M, Nurden P, Pillois X. Glanzmann thrombasthenia: a review ofITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, andmouse models. Blood. 2011 Dec 1;118(23):5996-6005. doi:10.1182/blood-2011-07-365635.
  2. Nurden AT, Pillois X, Fiore M, Alessi MC, Bonduel M, Dreyfus M, Goudemand J,Gruel Y, Benabdallah-Guerida S, Latger-Cannard V, Négrier C, Nugent D, Oiron RD, Rand ML, Sié P, Trossaert M, Alberio L, Martins N, Sirvain-Trukniewicz P, CoulouxA, Canault M, Fronthroth JP, Fretigny M, Nurden P, Heilig R, Vinciguerra C.Expanding the Mutation Spectrum Affecting αIIbβ3 Integrin in GlanzmannThrombasthenia: Screening of the ITGA2B and ITGB3 Genes in a Large International Cohort. Hum Mutat. 2015 May;36(5):548-61. doi: 10.1002/humu.22776.
  3. Nurden AT, Pillois X, Wilcox DA. Glanzmann thrombasthenia: state of the artand future directions. Semin Thromb Hemost. 2013 Sep;39(6):642-55. doi:10.1055/s-0033-1353393.
  4. Pillitteri D, Pilgrimm AK, Kirchmaier CM. Novel Mutations in the GPIIb andGPIIIa Genes in Glanzmann Thrombasthenia. Transfus Med Hemother.2010;37(5):268-277.
  5. Sandrock-Lang K, Oldenburg J, Wiegering V, Halimeh S, Santoso S, Kurnik K,Fischer L, Tsakiris DA, Sigl-Kraetzig M, Brand B, Bührlen M, Kraetzer K, Deeg N, Hund M, Busse E, Kahle A, Zieger B. Characterisation of patients with Glanzmannthrombasthenia and identification of 17 novel mutations. Thromb Haemost. 2015Apr;113(4):782-91. doi: 10.1160/TH14-05-0479.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Camila Xu
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Entry Collection: MedlinePlus
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Update Date: 23 Dec 2020
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