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HandWiki. 5-Oxo-Eicosatetraenoic Acid. Encyclopedia. Available online: https://encyclopedia.pub/entry/36925 (accessed on 21 September 2026).
HandWiki. 5-Oxo-Eicosatetraenoic Acid. Encyclopedia. Available at: https://encyclopedia.pub/entry/36925. Accessed September 21, 2026.
HandWiki. "5-Oxo-Eicosatetraenoic Acid" Encyclopedia, https://encyclopedia.pub/entry/36925 (accessed September 21, 2026).
HandWiki. (2022, November 29). 5-Oxo-Eicosatetraenoic Acid. In Encyclopedia. https://encyclopedia.pub/entry/36925
HandWiki. "5-Oxo-Eicosatetraenoic Acid." Encyclopedia. Web. 29 November, 2022.
5-Oxo-Eicosatetraenoic Acid
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The content is sourced from: https://handwiki.org/wiki/Chemistry:5-oxo-eicosatetraenoic_acid

5-Oxo-eicosatetraenoic acid (i.e. 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid; also termed 5-oxo-ETE and 5-oxoETE) is a Nonclassic eicosanoid metabolite of arachidonic acid and the most potent naturally occurring member of the 5-HETE family of cell signaling agents. Like other cell signaling agents, 5-oxo-ETE is made by a cell and then feeds back to stimulate its parent cell (see Autocrine signaling) and/or exits this cell to stimulate nearby cells (see paracrine signaling). 5-Oxo-ETE can stimulate various cell types particularly human leukocytes but possesses its highest potency and power in stimulating the human eosinophil type of leukocyte. It is therefore suggested to be formed during and to be an important contributor to the formation and progression of eosinophil-based allergic reactions; it is also suggested that 5-oxo-ETE may also contribute inflammation, cancer cell growth, and other pathophysiological responses.

eosinophil cell signaling inflammation

References

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