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The Mexican Health and Aging Study (MHAS), also known by its Spanish name, Estudio Nacional de Salud y Envejecimiento en México, ENASEM, is the first panel study of health and aging in Mexico. The first phase of MHAS (waves 1 and 2) was supported by a grant from the MHAS was supported by a grant from the National Institutes of Health/National Institute on Aging (AG 18016, BJ Soldo, PI). The study was a collaborative effort among researchers from the Universities of Pennsylvania, Maryland, and Wisconsin in the U.S., and the Instituto Nacional de Estadística, Geografia e Informática (INEGI, Mexico). The second phase of MHAS (waves 3 and 4) is supported by the National Institutes of Health/National Institute on Aging (R01AG018016, R Wong, PI) and by the INEGI in Mexico. The new study is a collaborative effort from the University of Texas Medical Branch (UTMB), Instituto Nacional de Estadística, Geografia e Informática (INEGI, Mexico), the University of Wisconsin, the Instituto Nacional de Geriatría (INGER, Mexico) and the Instituto Nacional de Salud Pública (INSP, Mexico).