Platelet Reactivity and Inflammatory Phenotype
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  • Release Date: 23 Dec 2022
  • platelet activation
  • platelet aggregation
  • SARS-CoV-2
Video Introduction

This video is adapted from 10.3390/ijms232315191

A state of immunothrombosis has been reported in COVID-19. Platelets actively participate in this process. Platelet-rich plasma (PRP) was incubated with spike full-length protein and the RBD domain in independent assays. Researchers evaluated platelet activation through the expression of P-selectin and activation of glycoprotein IIbIIIa (GP IIbIIIa), determined by flow cytometry and the ability of the proteins to induce platelet aggregation.

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Cano Mendez, A.F.;  Larragoiti, N.G.;  Vazquez, M.D.;  Cancino, P.G.;  Castaneda, S.E.L.; Ochoa-Zarzosa, A.;  Sandoval, M.E.V. Platelet Reactivity and Inflammatory Phenotype. Encyclopedia. Available online: (accessed on 03 March 2024).
Cano Mendez AF,  Larragoiti NG,  Vazquez MD,  Cancino PG,  Castaneda SEL, Ochoa-Zarzosa A, et al. Platelet Reactivity and Inflammatory Phenotype. Encyclopedia. Available at: Accessed March 03, 2024.
Cano Mendez, Alan Fabricio, Nallely García Larragoiti, María Damian Vazquez, Patricia Guzmán Cancino, Sandra Edith López Castaneda, Alejandra Ochoa-Zarzosa, Martha Eva Viveros Sandoval. "Platelet Reactivity and Inflammatory Phenotype" Encyclopedia, (accessed March 03, 2024).
Cano Mendez, A.F.,  Larragoiti, N.G.,  Vazquez, M.D.,  Cancino, P.G.,  Castaneda, S.E.L., Ochoa-Zarzosa, A., & Sandoval, M.E.V. (2022, December 23). Platelet Reactivity and Inflammatory Phenotype. In Encyclopedia.
Cano Mendez, Alan Fabricio, et al. "Platelet Reactivity and Inflammatory Phenotype." Encyclopedia. Web. 23 December, 2022.