Bone Microvascular Endothelial Cells
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  • Release Date: 2022-07-10
  • bone microvascular endothelial cells
  • glucocorticoid
  • icariin
Video Introduction

This video is adapted from 10.3390/cells11121921

Glucocorticoids could induce injury and apoptosis of bone microvascular endothelial cells (BMECs) in the femoral head, which is associated with the development of osteonecrosis and osteoporosis. Icariin is a prenylated flavonol glycoside isolated from Epimedium brevicornum, serving as the main active pharmaceutical constituent to treat bone loss. Currently, the impact of the autocrine activity of extracellular vesicles (EVs) induced by icariin on the glucocorticoid-induced injury of BMECs is still to be confirmed.

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Sun, W.;  Zhang, Q.;  Li, T.;  Li, Z.;  Lu, J.;  Wu, X.; Gao, F. Bone Microvascular Endothelial Cells. Encyclopedia. Available online: (accessed on 22 April 2024).
Sun W,  Zhang Q,  Li T,  Li Z,  Lu J,  Wu X, et al. Bone Microvascular Endothelial Cells. Encyclopedia. Available at: Accessed April 22, 2024.
Sun, Wei, Qingyu Zhang, Tengqi Li, Zirong Li, Jike Lu, Xinjie Wu, Fuqiang Gao. "Bone Microvascular Endothelial Cells" Encyclopedia, (accessed April 22, 2024).
Sun, W.,  Zhang, Q.,  Li, T.,  Li, Z.,  Lu, J.,  Wu, X., & Gao, F. (2022, July 10). Bone Microvascular Endothelial Cells. In Encyclopedia.
Sun, Wei, et al. "Bone Microvascular Endothelial Cells." Encyclopedia. Web. 10 July, 2022.