• Polar Chromosomes
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  • Release time: 2022-05-26
  • mitosis
  • mitotic spindle
  • prometaphase
  • aneuploidy
  • chromosome congression
  • chromosome mis-segregation
Video Introduction

The process of chromosome congression and alignment is at the core of mitotic fidelity. In this video, researchers discuss distinct spatial routes that the chromosomes take to align during prometaphase, which are characterized by distinct biomolecular requirements. Peripheral polar chromosomes are an intriguing case as their alignment depends on the activity of kinetochore motors, polar ejection forces, and a transition from lateral to end-on attachments to microtubules, all of which can result in the delayed alignment of these chromosomes.

This video is adapted from 10.3390/cells11091531

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Vukušić, K.; Tolić, I.M. Polar Chromosomes. Encyclopedia. Available online: https://encyclopedia.pub/video/video_detail/318 (accessed on 28 June 2022).
Vukušić K, Tolić IM. Polar Chromosomes. Encyclopedia. Available at: https://encyclopedia.pub/video/video_detail/318. Accessed June 28, 2022.
Vukušić, Kruno, Iva M. Tolić. "Polar Chromosomes," Encyclopedia, https://encyclopedia.pub/video/video_detail/318 (accessed June 28, 2022).
Vukušić, K., & Tolić, I.M. (2022, May 26). Polar Chromosomes. In Encyclopedia. https://encyclopedia.pub/video/video_detail/318
Vukušić, Kruno and Iva M. Tolić. ''Polar Chromosomes.'' Encyclopedia. Web. 26 May, 2022.