Neurons Induce Tiled Astrocytes
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  • Release Date: 2022-04-20
  • astrocyte
  • neuron
  • tiling
  • glutamate transporter
Video Introduction

This video is adapted from 10.3390/ijms23084161

Neurons induce astrocyte branches that approach synapses. Each astrocyte tiles by expanding branches in an exclusive territory, with limited entries for the neighboring astrocyte branches. However, how astrocytes form exclusive territories is not known. Here we show time-lapse imaging of the multi-order branching process of GFP-labeled astrocytes. Astrocyte branches grow in the direction where other astrocyte branches do not exist. Neurons just started to grow dendrites were able to induce astrocyte branching and tiling. Upon neuronal loss by glutamate excitotoxicity, astrocytes’ terminal processes retracted and more branches went over other branches. Our results indicate that neurons induce astrocyte branches and make them avoid each other.[1]

  1. Mariko Kato Hayashi; Kaoru Sato; Yuko Sekino; Neurons Induce Tiled Astrocytes with Branches That Avoid Each Other. International Journal of Molecular Sciences 2022, 23, 4161, 10.3390/ijms23084161.
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Hayashi, M. Neurons Induce Tiled Astrocytes. Encyclopedia. Available online: (accessed on 13 April 2024).
Hayashi M. Neurons Induce Tiled Astrocytes. Encyclopedia. Available at: Accessed April 13, 2024.
Hayashi, Mariko. "Neurons Induce Tiled Astrocytes" Encyclopedia, (accessed April 13, 2024).
Hayashi, M. (2022, April 20). Neurons Induce Tiled Astrocytes. In Encyclopedia.
Hayashi, Mariko. "Neurons Induce Tiled Astrocytes." Encyclopedia. Web. 20 April, 2022.