Aerosol-Mediated Non-Viral Lung Gene Therapy
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  • Release Date: 2022-03-25
  • aminoglycoside-based cationic lipids
  • cystic fibrosis
  • lipidic formulations
  • lung gene therapy
  • nebulization
  • structure-activity
  • in vivo
Video Introduction

This video is adapted from 10.3390/pharmaceutics14010025

The video shows the experimental procedure used to dose animals via aerosol, which allowed to highlight the potential of aminoglycoside-based cationic liposomes for non-viral lung gene therapy.

All procedures were carried out with personal licenses under protocols (APAFIS #22194-2019092711061392) approved by the Laboratory Animal Care Guidelines and the Institutional Animal Care and Research Advisory Committee at both the University of Oxford (United Kingdom) and the University of Brest (France).

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Le Gall, T.; Berchel, M.; Mottais, A.; Ghanem, R.; Benvegnu, T.; Montier, T. Aerosol-Mediated Non-Viral Lung Gene Therapy. Encyclopedia. Available online: (accessed on 15 April 2024).
Le Gall T, Berchel M, Mottais A, Ghanem R, Benvegnu T, Montier T. Aerosol-Mediated Non-Viral Lung Gene Therapy. Encyclopedia. Available at: Accessed April 15, 2024.
Le Gall, Tony, Mathieu Berchel, Angélique Mottais, Rosy Ghanem, Thierry Benvegnu, Tristan Montier. "Aerosol-Mediated Non-Viral Lung Gene Therapy" Encyclopedia, (accessed April 15, 2024).
Le Gall, T., Berchel, M., Mottais, A., Ghanem, R., Benvegnu, T., & Montier, T. (2022, March 25). Aerosol-Mediated Non-Viral Lung Gene Therapy. In Encyclopedia.
Le Gall, Tony, et al. "Aerosol-Mediated Non-Viral Lung Gene Therapy." Encyclopedia. Web. 25 March, 2022.