The age of the Internet of Things (IoT) and smart cities calls for low-power wireless communication networks, for which the Long-Range (LoRa) is a rising star. Efficient network engineering requires the accurate prediction of the Received Signal Strength Indicator (RSSI) spatial distribution. However, the most commonly used models either lack the physical accurateness, resolution, or versatility for cityscape real-world building distribution-based RSSI predictions. For this purpose, authors apply the 2D electric field wave-propagation Oscillator Finite-Difference Time-Domain (O-FDTD) method, using the complex dielectric permittivity to model reflection and absorption effects by concrete walls and the receiver sensitivity as the threshold to obtain a simulated coverage area in a 600 × 600 m2 square. Further, authors report a simple and low-cost method to experimentally determine the signal coverage area based on mapping communication response-time delays. The simulations show a strong building influence on the RSSI, compared against the Free-Space Path (FSPL) model. Authors obtain a spatial overlap of 84% between the O-FDTD simulated and experimental signal coverage maps. Authors' proof-of-concept approach is thoroughly discussed compared to previous works, outlining error sources and possible future improvements. O-FDTD is demonstrated to be most promising for both indoors and outdoors applications and presents a powerful tool for IoT and smart city planners.