Alcohol, Cognition and Bipolar Disorder
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  • Release Date: 2021-10-08
  • cognition
  • visual memory
  • reaction time
  • alcohol
  • bipolar disorder
Video Introduction

This video is adapted from 10.3390/brainsci11091154

The study population included 1268 persons from Finland with bipolar disorder. Alcohol use was assessed through hazardous drinking and alcohol-related disorder including alcohol use disorder (AUD). Hazardous drinking was screened with the Alcohol Use Disorders Identification Test for Consumption (AUDIT-C) screening tool. Alcohol-related disorder diagnoses were obtained from the national registrar data. Participants performed two computerized tasks from the Cambridge Automated Neuropsychological Test Battery (CANTAB) on A tablet computer: the 5-choice serial reaction time task, or reaction time (RT) test and the Paired Associative Learning (PAL) test. Depressive symptoms were assessed with the Mental Health Inventory with five items (MHI-5). However, no assessment of current manic symptoms was available. Association between RT-test and alcohol use was analyzed with log-linear regression, and eβ with 95% confidence intervals (CI) are reported. PAL first trial memory score was analyzed with linear regression, and β with 95% CI are reported. PAL total errors adjusted was analyzed with logistic regression and odds ratios (OR) with 95% CI are reported. After adjustment of age, education, housing status and depression, hazardous drinking was associated with lower median and less variable RT in females while AUD was associated with a poorer PAL test performance in terms of the total errors adjusted scores in females.

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Mazumder, A.; Kerkelä, M.; Häkkinen, K.; Vainio, S.; Veijola, J. Alcohol, Cognition and Bipolar Disorder. Encyclopedia. Available online: (accessed on 18 June 2024).
Mazumder A, Kerkelä M, Häkkinen K, Vainio S, Veijola J. Alcohol, Cognition and Bipolar Disorder. Encyclopedia. Available at: Accessed June 18, 2024.
Mazumder, Atiqul, Martta Kerkelä, Katja Häkkinen, Seppo Vainio, Juha Veijola. "Alcohol, Cognition and Bipolar Disorder" Encyclopedia, (accessed June 18, 2024).
Mazumder, A., Kerkelä, M., Häkkinen, K., Vainio, S., & Veijola, J. (2021, October 08). Alcohol, Cognition and Bipolar Disorder. In Encyclopedia.
Mazumder, Atiqul, et al. "Alcohol, Cognition and Bipolar Disorder." Encyclopedia. Web. 08 October, 2021.
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