This cross-sectional video explores the oral-health-related quality of life (OHRQoL) among patients with fixed, removable, and combined dental prosthetic restorations in Osijek, Croatia, examining potential variations by gender, age, and prosthetic type. The study featured 313 patients treated at dental clinics within the Osijek-Baranja County Health Center, using the standardized Oral Health Impact Profile-14 (OHIP-14) questionnaire, validated in Croatian (OHIP-CRO14), to assess their OHRQoL. Statistical analyses were conducted to identify associations between demographic factors, prosthetic types, and different OHRQoL domains. The findings reveal that psychological discomfort was the domain with the lowest reported OHRQoL, while social disability was the least affected. Gender did not show a significant association with OHRQoL outcomes, but age played a notable role. Patients with fixed prosthetic restorations reported better OHRQoL in functional limitation, physical pain, and physical disability compared to those with removable or combined prosthetics. The video highlights that fixed prosthetic restorations contribute to improved OHRQoL, particularly in functional and physical aspects. While no major gender differences were observed, age significantly influenced physical disability scores, with younger participants reporting lower scores and older participants higher ones. These insights underscore the importance of prosthetic type in enhancing OHRQoL and can help guide clinical decision-making in dental practice.