Division of Neurosurgery and Traumatology, Department of Surgery, Kuang Tien General Hospital, Taichung 43303, Taiwan

Department of Biotechnology and Animal Science, College of Bioresources, National Ilan University, Yilan 26047, Taiwan

Department of Biotechnology, College of Medical and Health Care, Hung Kuang University, Taichung 43302, Taiwan

Department of Health Business Administration, College of Medical and Health Care, Hung Kuang University, Taichung 43302, Taiwan