Frequently, the addition/subtraction of water molecules to matter modifies the matter nature. For example, there are many molecules capable ‘to mutate’ in presence of water or a dehydrating agent. All inorganic substances (i.e., oxides, hydroxides, anhydrides, acids, etc.) are generated by the addition/subtraction of one water molecule to another chemical compound. Similarly, in organic chemistry, a very common type of reaction is the ‘condensation reaction’, that is the reaction between two molecules to produce a product and water. Examples of this type of reaction is the Fischer esterification, the peptide bond formation, the polymerization by polycondensation, etc. The inverse reaction does also exist for each of these processes; indeed, inverse types of reactions are hydrolysis and saponification, where water addition to a molecule generates two new molecules. In general, matter (i.e., elemental substances, molecules, polymers and other types of substances) can modify in presence of water. Like an example, in the above picture, it is shown as water removal from a poly(vinyl alcohol) (PVOH) film by dipping in concentrated sulfuric acid leads to the formation of a polyacetylene film^[1].