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Esterification Reactions: History
Please note this is an old version of this entry, which may differ significantly from the current revision.
Subjects: Chemistry, Organic
Contributor: Helena Kang

Ethers are characterized by an oxygen atom bonded to two alkyl or aryl groups, serving as versatile solvents and reagents in organic synthesis and reaction mechanisms [1]. Its defining scope is the molecular transformation, structure, or mechanistic feature stated in that description; a reagent, catalyst, solvent, or processing condition is not itself the concept unless it determines that defining feature. At the molecular level, the classification depends on the identity of the participating functional groups and on the connectivity or stereochemical change that distinguishes the product or intermediate. Related variants may differ in substrate class, catalyst, or elementary pathway while retaining the same central structural criterion [2]. The term therefore has a narrower meaning than general chemical reactivity: processes that merely share a reagent, reaction condition, or product family belong to the concept only when they satisfy the same defining bond change or structural criterion. This boundary separates the concept from neighboring transformations that alter a similar functional group by a different net pathway. The description identifies the chemical class itself and does not prescribe a single experimental protocol.

  • ether compounds
  • C–O–C linkage
  • ether synthesis

Chemical Synthesis and Analysis • Molecular Biology • Biochemistry, Genetics and Molecular Biology • Life Sciences

References

  1. Hiyoshizo Kotsuki; Yoshikatsu Ichikawa; Mitsuhiro Iwasaki; Masanori Kataoka; Hitoshi Nishizawa; High pressure organic chemistry; XV. Non-catalyzed cleavage reaction of ethers with acyl halides. High Press. Res. 1993, 11, 107-118, 10.1080/08957959208201696.
  2. Hiyoshizo Kotsuki; Yoshikatsu Ichikawa; Hitoshi Nishizawa; Non-Catalyzed Cleavage Reactions of Ethers with Acyl Halides under High-Pressure Conditions. Chem. Lett. 1988, 17, 673-676, 10.1246/cl.1988.673.
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