Cellular engineering is the deliberate design, modification, preparation, and organization of living cells to generate controlled cellular behaviors and tissue-forming functions within tissue engineering and regenerative medicine. Its scope includes the selection and expansion of appropriate cell populations; modulation of cell phenotype, proliferation, survival, migration, differentiation, and secretory activity; and control of cell–cell and cell–extracellular-matrix interactions ^[1][2]. Cellular engineering integrates biochemical, genetic, and biophysical inputs, including soluble signaling factors, gene-delivery or genome-modification systems, biomaterial interfaces, mechanical stimuli, and spatial patterning, to establish defined cellular states and multicellular architectures ^[2][3][4]. In this context, cells constitute active biological components whose functions are specified through interactions with engineered microenvironments and with other cells during the formation, maintenance, or restoration of tissue-like organization ^[1][3].