Transcription termination is the regulated completion of RNA synthesis at which an RNA polymerase ceases nucleotide addition, releases the nascent RNA transcript, and dissociates from the DNA template or transitions from the transcription unit through polymerase recycling pathways. It is executed by termination signals encoded in DNA and nascent RNA together with conformational changes in the transcription elongation complex and, in many systems, accessory proteins or RNA-processing complexes ^[1]. These molecular events destabilize the interactions among RNA polymerase, the RNA–DNA hybrid, the transcription bubble, and template DNA, thereby resolving the elongation complex at defined genomic positions ^[1][2]. In bacteria, termination includes intrinsic pathways directed by terminator RNA structures and uridine-rich RNA sequences, as well as pathways involving ATP-dependent RNA translocases such as Rho ^[2][3]. In eukaryotic RNA polymerase II transcription, cleavage of the nascent RNA at polyadenylation-associated sites and exonucleolytic degradation of the downstream RNA contribute to polymerase release ^[4].