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Antimicrobial Properties: History
Please note this is an old version of this entry, which may differ significantly from the current revision.
Contributor: Jack Zhong

Antimicrobial properties are the effects by which a material suppresses the growth of, or kills, microorganisms that come into contact with it, and they are reported as an inhibition zone, a minimum inhibitory concentration, or a reduction in viable count over a stated contact time. Oxide and metal nanoparticles dispersed in a polymer matrix act through several routes at once: release of metal ions, generation of reactive oxygen species, and direct contact with the cell envelope, so a hybrid of oxide nanoparticles in chitosan shows activity against both Gram-positive and Gram-negative strains [1]. For silver the released ion is the dominant agent, and the rate at which the particle dissolves oxidatively therefore controls how long the effect lasts [2]. Chitosan contributes its own polycationic action and, when combined with a plant extract, also carries antioxidant activity [3]. Bringing such particles into a food-contact film raises the question of how much silver migrates out of it [4]. Composite films of gelatin and chitosan nanoparticles extend the same approach to edible packaging [5].

  • antibacterial activity
  • metal nanoparticle
  • silver ion release
  • chitosan film
  • inhibition zone
  • minimum inhibitory concentration
  • reactive oxygen species

 

 

References

  1. Matyjasik, W.; Długosz, O.; Lis, K.; Banach, M.; Nanohybrids of oxides nanoparticles-chitosan and their antimicrobial properties. Nanotechnology 2022, 33, 435701, 10.1088/1361-6528/ac805e.
  2. Zaheer, Z.; Chitosan-capped silver nanoparticles: fabrication, oxidative dissolution, sensing properties, and antimicrobial activity. Journal of Polymer Research 2021, 28, 348, 10.1007/s10965-021-02673-0.
  3. Khodaparast, F.K.; Pirsa, S.; Toupchi, F.M.; Mohtarami, F.; Investigating the physicochemical, antimicrobial and antioxidant properties of chitosan film containing zero‐valent iron nanoparticles and oregano essence. Biopolymers 2024, 115, e23614, 10.1002/bip.23614.
  4. Demirbas, A.; Karsli, B.; Innovative chitosan-silver nanoparticles: Green synthesis, antimicrobial properties, and migration assessment for food packaging. Food Chemistry 2025, 467, 142363, 10.1016/j.foodchem.2024.142363.
  5. Hosseini, S.F.; Rezaei, M.; Zandi, M.; Farahmandghavi, F.; Development of bioactive fish gelatin/chitosan nanoparticles composite films with antimicrobial properties. Food Chemistry 2016, 194, 1266-1274, 10.1016/j.foodchem.2015.09.004.
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